Have questions? We're here.
Boat floating along the Mekong River

Top Mekong River Trips & Tours in October 2025

Travel made your way
Talk with an expert
Build your ideal Mekong River trip. Call 1.406.541.2677
Start Planning My Trip
Discover Mekong River in October 2025 on one of these 32 tours hand-selected by the travel experts at Adventure Life. Explore the best of during October 2025 as you enjoy Village Visits, Local Market Visits, Archaeological Site Visits, Biking, and Wildlife Viewing. Prices for trips in October 2025 range from $990 to $23,290 for a vacation of 5 to 16 days. Choose any of the below 32 itineraries in October 2025 and customize it when you contact one of Adventure Life's expert Mekong River trip planners.
Filter (32 Results)
  • Start Date
    OR, More specific start
  • Length
    to
  • Price
    to
  • Activity Levels
  • Experiences
  • Activities
  • Ships
  • Destinations
    • Mekong River
The beautiful Vinh Trang temple near My Tho
from $4,299
EXPLORE

Mekong River - Upstream - High water

Saigon - Siem Reap - 8 Day Itinerary aboard The Jahan
Starts / Ends
Ho Chi Minh City / Siem Reap
Activities
Cooking Classes
Activity Level
Variable
Experience the Mekong River during the high water season on this 8-day cruise on The Jahan. This expedition takes you from Saigon to Siem Reap, allowing you to discover the lower Mekong and its fascinating towns while learning about their diverse cultures and rich history.
  • Aboard a luxury riverboat in Mekong
  • See the floating market in Cai Be
  • Observed locals along the river
  • Visit Phnom Penh cultural sites
Cruise Details
0
Flower farms in Sa Dec, Vietnam
from $3,788
EXPLORE

Mekong River - Upstream - High water

Saigon to Siem Reap - 8 Day Itinerary aboard Jayavarman
Starts / Ends
Ho Chi Minh City / Siem Reap
Activity Level
Variable
Embark on this 8-day high river expedition on the Jayavarman and experience the Mekong River as it flows from Saigon to Siem Reap. Explore the lower Mekong and discover the diverse cultures and historical significance of the towns along its course.
  • Explore rural villages
  • Discover skilled craftsmanship
  • Experience scenic views at Delta
  • Explore floating markets
  • Discover cultures of Mekong Delta
Cruise Details
0
Phnom Penh Royal Palace complex
from $2,124
EXPLORE

Mekong River - Upstream

Saigon to Phnom Penh - 4 Day Itinerary aboard The Jahan
Starts / Ends
Ho Chi Minh City / Phnom Penh
Activity Level
Variable
On this 4-day journey from Saigon to Phnom Penh, cruise the lower Mekong River in majestic style aboard the Jahan. Discover the culture and history of the various towns along the mighty Mekong while exploring the river.
  • Observed locals along the river
  • See the floating market in Cai Be
  • Visit Phnom Penh cultural sites
  • Visit Tan Chau floating fish farm
Cruise Details
0
Sunset over the Mekong River
from $3,788
EXPLORE

Mekong River - Downstream - High water

Siem Reap to Saigon - 8 Day Itinerary aboard Jayavarman
Starts / Ends
Siem Reap / Ho Chi Minh City
Activity Level
Variable
Explore the Mekong on this 8-day high-water Mekong River cruise from Siem Reap to Saigon. Get an inside look at the southern cultures of Vietnam and Cambodia as you travel across the mighty Mekong Delta. Stop in charming port towns and immerse yourself in the city's culture and history.
  • Aboard a luxury riverboat in Mekong
  • See the floating market in Cai Be
  • Observed locals along the river
  • Visit Tan Chau floating fish farm
  • Visit Phnom Penh cultural sites
Cruise Details
0
Phnom Penh Royal Palace complex
from $1,956
EXPLORE

Mekong River - Upstream

Saigon to Phnom Penh - 4 Day Itinerary aboard Jayavarman
Starts / Ends
Ho Chi Minh City / Phnom Penh
Activity Level
Variable
On this 4-day journey from Saigon to Phnom Penh, cruise the lower Mekong River in majestic style aboard the Jayavarman. Discover the culture and history of the various towns along the mighty Mekong while exploring the river.
  • Observed locals along the river
  • See the floating market in Cai Be
  • Visit Phnom Penh cultural sites
  • Visit Tan Chau floating fish farm
Cruise Details
0
Floating Market in Cai Be
from $4,299
EXPLORE

Mekong River - Downstream - High water

Siem Reap to Saigon - 8 Day Itinerary aboard The Jahan
Starts / Ends
Siem Reap / Ho Chi Minh City
Activity Level
Variable
Join this 8-day Mekong River cruise during the high water season from Siem Reap to Saigon. Get an inside look at the southern cultures of Vietnam and Cambodia as you travel across the mighty Mekong delta. Stop in charming port towns and immerse yourself in the city's culture and history.
  • Aboard a luxury riverboat in Mekong
  • See the floating market in Cai Be
  • Observed locals along the river
  • Visit Tan Chau floating fish farm
  • Visit Phnom Penh cultural sites
Cruise Details
0
Royal Palace and Silver Pagoda
from $1,956
EXPLORE

Mekong River - Downstream

Phnom Penh to Saigon - 4 Day Itinerary aboard Jayavarman
Starts / Ends
Phnom Penh / Ho Chi Minh City
Activity Level
Variable
Cruise downstream on the Mekong River in majestic style aboard the Jayavarman on this 4-day journey from Phnom Penh to Saigon. Learn about the culture and heritage with visits to rural villages, historic pagodas, and colorful markets
  • Observed locals along the river
  • Aboard a luxury riverboat in Mekong
  • Visit Phnom Penh cultural sites
  • Visit Tan Chau floating fish farm
Cruise Details
0
Floating village in Southeast Asia
from $2,292
EXPLORE

Mekong River - Downstream - High water

Siem Reap to Phnom Penh - 5 Day Itinerary aboard Jayavarman
Starts / Ends
Siem Reap / Phnom Penh
Activity Level
Variable
From Siem Reap to Phnom Penh, join this 5-day High Water Mekong river cruise aboard the Jayavarman and journey through the vast Mekong Delta to explore the historic pre-Angkorian temples and Cambodian culture.
  • Observed locals along the river
  • Aboard a luxury riverboat in Mekong
  • Visit Phnom Penh cultural sites
  • Visit a local home in Kampong Cham
Cruise Details
0
Traditional mat-making
from $2,124
EXPLORE

Mekong River - Downstream

Phnom Penh to Saigon - 4 Day Itinerary aboard The Jahan
Starts / Ends
Phnom Penh / My Tho
Activity Level
Variable
On this 4-day journey from Phnom Penh to Saigon, cruise downstream on the lower Mekong River in majestic style aboard the Jahan. See the stunning scenery and discover the culture and history of the various towns along the mighty Mekong.
  • Experience Binh Thanh Island
  • Explore My An Hung Village
  • Discover Tan Chau
  • Experience Cao Dai
Cruise Details
0
Sunset over the Mekong River
from $3,358
EXPLORE

Classic Mekong

Upstream - 8 Day Itinerary aboard RV Bassac Pandaw
Starts / Ends
Ho Chi Minh City / Siem Reap
Activities
Fishing
Activity Level
Variable
Explore both Vietnam's and Cambodia's striking cultural contrast in this 8-day Upstream Classic Mekong Cruise from Saigon to Siem Reap aboard RV Bassac Pandaw. Travel from the vibrant French colonial port of Saigon through the vast delta so rich in human life and endeavor to the rich countryside of Cambodia.
  • Explore the floating markets
  • Explore riverside villages
  • See Phnom Penh's National Museum
Cruise Details
0
Royal Palace and Silver Pagoda
from $2,502
EXPLORE

Mekong River - Downstream - High water

Siem Reap to Phnom Penh - 5 Day Itinerary aboard The Jahan
Starts / Ends
Siem Reap / Phnom Penh
Activity Level
Variable
Join this 5-day high water river cruise aboard the Jahan from Siem Reap to Phnom Penh, and travel across the mighty Mekong Delta to discover the ancient pre-Angkorian temples and Cambodian culture.
  • Observed locals along the river
  • Aboard a luxury riverboat in Mekong
  • Visit Phnom Penh cultural sites
  • Visit a local home in Kampong Cham
Cruise Details
0
Cycling along the bridge
from $1,475
EXPLORE

Cycling the Mekong Delta

Vietnam Small Group Tour - 8 Day Itinerary
Starts / Ends
Ho Chi Minh City / Ho Chi Minh City
Activities
Biking, Local Market Visits, Archaeological Site Visits, Homestays, Urban Exploration
Activity Level
Moderate
Discover the heart of Vietnam in the enchanting Mekong Delta on an unforgettable 8-day small group cycling adventure from Ho Chi Minh City to Chau Doc. Immerse yourself in scenic landscapes and vibrant cultures as you pedal through picturesque paths. Uncover the beauty of traditional villages, witness the rhythm of local life, and savor the flavors of authentic cuisine.
  • Explore Ho Chi Minh City
  • See the floating market in Cai Be
  • Visit the Khmer templ in Tra Vinh
  • Explore Can Tho's charming villages
  • See the rice paddies in Long Xuyen
  • Discover Chau Doc' diverse culture
Tour Details
0
Everyday life in Vietnam
from $3,439
EXPLORE

Charms of the Mekong - Cruise Only

Ho Chi Minh - Siem Reap - 8 Day Itinerary aboard MS Amadara
Starts / Ends
Ho Chi Minh City / Siem Reap
Activity Level
Variable
Embark on an 8-day river cruise aboard the MS Amadara, starting in Ho Chi Minh City, a vibrant blend of history and modernity. Cruise the Mekong River, exploring villages, pagodas, and markets and experiencing local traditions, including a monk’s blessing and artisan crafts.
  • Explore Cai Be’s vibrant workshops
  • Discover Sa Dec history
  • Visit Phnom Penh landmarks
  • Experience Oknhatey, silk weaving
Cruise Details
0
The beautiful Angkor Wat
from $10,290
NO SS
EXPLORE

Mekong Expedition - Siem Reap to Ho Chi Minh

8 Day Itinerary aboard Aqua Mekong
Activities
Wildlife Viewing
Activity Level
Variable
This 8-day cultural cruise aboard the Aqua Mekong takes you from Siem Reap, Cambodia to Ho Chi Minh City, Vietnam, stopping at Tonle Sap Lake and other local destinations of interest along the Mekong River. You will visit Prek Toal Core, sail into Chhnok Tru, a true floating village, and see Cambodia's capital by motorized tuk-tuk.
  • Visit Prek Toal Core Bird Reserve
  • Sail to floating village Chhnok Tru
  • See Cambodia's capital & sights
  • Meet & interact with locals
Cruise Details
0
Kampong Chhnang
from $6,418
EXPLORE

Charms of the Mekong

16 Day Itinerary aboard MS Amadara
Starts / Ends
Ho Chi Minh City / Hanoi
Activities
Land & Sea Exploration
Activity Level
Variable
Embark on a 16-day cruise aboard the MS Amadara. Explore the Mekong, visit rural villages and ancient temples, and discover Angkor’s UNESCO sites in Siem Reap before concluding with an overnight stay at Ha Long Bay.
  • Explore Ho Chi Minh vibrant city
  • Visit Phnom Penh historic palaces
  • Discover Cai Be markets
  • Tour Siem Reap ancient temples
Cruise Details
0
Vietnam's bird sanctuary
from $10,290
NO SS
EXPLORE

Mekong Expedition - Ho Chi Minh to Siem Reap

High water - 8 Day Itinerary aboard Aqua Mekong
Starts / Ends
Ho Chi Minh City / Siem Reap
Activity Level
Variable
Board the Aqua Mekong for an unforgettable 8-day cruise up the Mekong River from Saigon, Vietnam to Siem Reap, Cambodia, with stops in Phnom Penh and Tonle Sap Lake, among other highlights of the Indochina peninsula. Biking, hiking, cultural immersion, market visits, and cooking classes highlight the cruise.
  • Experience vibrant markets
  • Enjoy touring Cambodia's capital
  • Visit Long Son Pagoda
  • Explore Prek Toal Core Bird Reserve
Cruise Details
0
Sanctuary Spa
from $990
EXPLORE

Farm House Resort and Spa Extension

4 Day Itinerary
Starts / Ends
Phnom Penh / Kampong Chhnang
Activities
Spa Relaxation, Village Visits
Activity Level
Relaxed
This 4-day tour starts in Phnom Penh or Battambang. Drive about 1 hour and 30 minutes from Phnom Penh or 4 hours from Battambang. Upon arrival, settle into the Smiling Gecko Farmhouse. Relax and enjoy the natural surroundings and delicious meals provided throughout your stay.
  • Discover Kampong Chhnang
  • Relax at the Farmhouse Resort & Spa
  • Support local Cambodians
Tour Details
0
The colorful Tonle Sap village
from $6,200
EXPLORE

Mekong Explorer - Siem Reap to Phnom Penh

5 Day Itinerary aboard Aqua Mekong
Activity Level
Variable
Embark the Aqua Mekong on this 5-day voyage down the Mekong River from Siem Reap to Phnom Penh. Stop in charming floating villages, interact with the local peoples of the area, and explore the colorful markets and cultural sites which line the shores.
  • Visit Prek Toal Core Bird Reserve
  • Meet and interact with locals
  • Attend a Buddhist blessing ceremony
Cruise Details
0
1-18 of 32 Results

Top Mekong River Travel Destinations

Mekong River Trips by Departure Date

Top Experiences in Mekong River

Mekong River Trips by Duration

Mekong River Trips by Activity

More Reasons

Why Travel With Adventure Life

All News

Recognized By