Have questions? We're here.
Boat floating along the Mekong River

Top Mekong River Trips & Tours in October 2026

Travel made your way
Talk with an expert
Build your ideal Mekong River trip. Call 1.406.541.2677
Start Planning My Trip
Discover Mekong River in October 2026 on one of these 50 tours hand-selected by the travel experts at Adventure Life. Explore the best of during October 2026 as you enjoy Village Visits, Local Market Visits, Archaeological Site Visits, Wildlife Viewing, and Land & Sea Exploration. Prices for trips in October 2026 range from $0 to $25,395 for a vacation of 5 to 16 days. Choose any of the below 50 itineraries in October 2026 and customize it when you contact one of Adventure Life's expert Mekong River trip planners.
Filter (50 Results)
  • Start Date
    OR, More specific start
  • Length
    to
  • Price
    to
  • Activity Levels
  • Experiences
  • Activities
  • Ships
  • Destinations
    • Mekong River
Phnom Penh Royal Palace complex
from $2,336
EXPLORE

Mekong River - Upstream

Saigon to Phnom Penh - 4 Day Itinerary aboard The Jahan
  • Observed locals along the river
  • See Cai Be’s rice & candy making
  • Explore the Gieng Island
  • Visit Phnom Penh cultural sites
Starts / Ends
Ho Chi Minh City / Phnom Penh
Activity Level
Variable
On this 4-day journey from Saigon to Phnom Penh, cruise the lower Mekong River in majestic style aboard the Jahan. Discover the culture and history of the various towns along the mighty Mekong while exploring the river.
Cruise Details
0
Sunset over the Mekong River
from $4,105
EXPLORE

Classic Mekong

Upstream - 8 Day Itinerary aboard RV Bassac Pandaw
  • Explore the floating fish farms
  • Discover Ben Tre orchards
  • See Phnom Penh's National Museum
  • Tour local pottery village
Starts / Ends
Ho Chi Minh City / Siem Reap
Activities
Fishing
Activity Level
Variable
Explore both Vietnam's and Cambodia's striking cultural contrast in this 8-day Upstream Classic Mekong Cruise from Saigon to Siem Reap aboard RV Bassac Pandaw. Navigate the Mekong and Tonle Sap Rivers, visit historic temples, rural villages, floating fish farms, and bustling markets.
Cruise Details
0
Everyday life in Vietnam
from $3,649
EBD $4000
EXPLORE

Charms of the Mekong - Cruise Only

Ho Chi Minh - Siem Reap - 8 Day Itinerary aboard MS Amadara
  • Explore Cai Be’s vibrant workshops
  • Discover Sa Dec history
  • Visit Phnom Penh landmarks
  • Experience Oknhatey, silk weaving
Starts / Ends
Ho Chi Minh City / Siem Reap
Activity Level
Variable
Embark on an 8-day river cruise aboard the MS Amadara, starting in Ho Chi Minh City, a vibrant blend of history and modernity. Cruise the Mekong River, exploring villages, pagodas, and markets and experiencing local traditions, including a monk’s blessing and artisan crafts.
Cruise Details
0
Royal Palace and Silver Pagoda
from $2,133
EXPLORE

Mekong River - Downstream

Phnom Penh to Saigon - 4 Day Itinerary aboard Jayavarman
  • Observed locals along the river
  • Aboard a luxury riverboat in Mekong
  • Visit Phnom Penh cultural sites
  • Visit the Gieng Island
Starts / Ends
Phnom Penh / Ho Chi Minh City
Activity Level
Variable
Cruise downstream on the Mekong River in majestic style aboard the Jayavarman on this 4-day journey from Phnom Penh to Saigon. Learn about the culture and heritage with visits to rural villages, historic pagodas, and colorful markets
Cruise Details
0
Vietnam's bird sanctuary
from $10,570
EXPLORE

Mekong Expedition - Ho Chi Minh to Siem Reap

High water - 8 Day Itinerary aboard Aqua Mekong
  • Experience vibrant markets
  • Enjoy touring Cambodia's capital
  • Visit Long Son Pagoda
  • Explore Prek Toal Core Bird Reserve
Starts / Ends
Ho Chi Minh City / Siem Reap
Activity Level
Variable
Board the Aqua Mekong for an unforgettable 8-day cruise up the Mekong River from Saigon, Vietnam, to Siem Reap, Cambodia, with stops in Phnom Penh and Tonle Sap Lake, among other highlights of the Indochina peninsula. Biking, hiking, cultural immersion, market visits, and cooking classes highlight the cruise.
Cruise Details
0
Traditional mat-making
from $2,336
EXPLORE

Mekong River - Downstream

Phnom Penh to Saigon - 4 Day Itinerary aboard The Jahan
  • Hear Khmer Rouge survivor story
  • Explore Gieng Island
  • Explore My An Hung Village
  • Discover water hyacinth weaving
  • Experience Tan Phong Island
Starts / Ends
Phnom Penh / Ho Chi Minh City
Activities
Biking
Activity Level
Variable
On this 4-day journey from Phnom Penh to Saigon, cruise downstream on the lower Mekong River in majestic style aboard the Jahan. See the stunning scenery and discover the culture and history of the various towns along the mighty Mekong.
Cruise Details
0
The Vinh Trang Temple in My Tho, Vietnam
from $3,949
EXPLORE

From the Angkor Temples to the Mekong Delta

Siem Reap - Ho Chi Minh - 11 Day Itinerary aboard RV Indochine
  • Visit the Banteay Srei temple
  • Explore the terrace of Elephants
  • Discover Kampong Chhnang
  • Tour Phnom Penh's National Museum
Starts / Ends
Siem Reap / Ho Chi Minh City
Activity Level
Variable
Experience an 11-day cruise on the RV Indochine from Siem Reap to Ho Chi Minh City, navigating over 2,700 miles of the Mekong River. Explore cultural landmarks like Angkor and Phnom Penh, all while enjoying colonial-inspired comfort aboard your vessel.
Cruise Details
0
Woman on a boat in Vietnam
from $2,659
EXPLORE

From the Mekong Delta to Siem Reap

Ho Chi Minh City - Siem Reap - 9 Day Itinerary aboard RV Indochine II
  • Join a tour of Ho Ci Minh City
  • Observe Chau Doc´s vibrant market
  • Experience a trip in a “tuk tuk”
  • See Kampong Chhnang´s fish farms
Activity Level
Variable
Discover the culture and history of Vietnam & Cambodia on this 9-day cruise from Ho Chi Minh City to Siem Reap aboard the RV Indochine II, departing from Vietnam's Ho Chi Minh City towards Cambodia's Siem Reap, with stops in My Tho & Phnom Penh along the way.
Cruise Details
0
Enjoy the Mekong’s tranquil waters as colorful blooms and a rustic riverside home set a relaxed, local vibe.
from $3,649
EBD $4000
EXPLORE

Riches of the Mekong - Cruise Only

8 Day Itinerary aboard MS Amadara
  • Explore Angkor Ban village
  • Visit Oknhatey, Silk Island
  • Tour Phnom Penh highlights
  • Discover Oudong, royal capital
Starts / Ends
Siem Reap / Ho Chi Minh City
Activities
Wildlife Viewing
Activity Level
Variable
Embark on an 8-day river cruise from Siem Reap to Ho Chi Minh aboard the MS Amadara, exploring rural villages, bustling markets, and historic sites. Experience Cambodia and Vietnam’s rich culture through artisan crafts, temple visits, and unique rides by oxcart, tuk-tuk, and trishaw.
Cruise Details
0
The floating village of Tonle Sap, Cambodia
from $6,400
EXPLORE

Mekong Explorer - Ho Chi Minh to Siem Reap (Extension)

5 Day Itinerary aboard Aqua Mekong
  • Enjoy a visit to a local's home
  • Walk through verdant plantations
  • Meet & interact with Buddhist Monks
  • Bike through Long Khanh
Starts / Ends
Ho Chi Minh City / Phnom Penh
Activity Level
Variable
Board the Aqua Mekong in My Tho for a 5-day Mekong River cruise of Cambodia & Vietnam, including stops in Ho Chi Minh City, Phnom Penh, and Long Son Pagoda atop Sam Mountain. Travel back in time as you cruise upriver through the thriving Mekong Delta past floating villages, colonial vestiges, and gilded pagodas.
Cruise Details
0
Flower farms in Sa Dec, Vietnam
from $2,539
EXPLORE

From the Mekong Delta to Siem Reap

Ho Chi Minh City to Siem Reap - 9 Day Itinerary aboard RV Indochine
  • Visit Ho Chi Minh landmarks
  • Cruise across Tonle Sap Lake
  • Explore Sa Dec’s Huynh Thuy Le
  • Visit Chau Doc temples
Starts / Ends
Ho Chi Minh City / Siem Reap
Activities
Urban Exploration
Activity Level
Variable
Embark on a 9-day Mekong River cruise aboard RV Indochine through Vietnam and Cambodia. Begin in Ho Chi Minh City and travel to Siem Reap, exploring temples, pagodas, markets, floating villages, and cultural landmarks along the way. Enjoy guided city tours, traditional crafts, and authentic cuisine.
Cruise Details
0
The Vinh Trang Temple in My Tho, Vietnam
from $2,539
EXPLORE

From Siem Reap to the Mekong Delta

Siem Reap to Ho Chi Minh City - 9 Day Itinerary aboard RV Indochine
  • Visit Koh Chen village
  • Explore Chau Doc’s pagodas
  • Visit Cai Be workshops
  • Discover Ho Chi Minh landmarks
Starts / Ends
Siem Reap / Ho Chi Minh City
Activity Level
Variable
Set sail on a 9-day Mekong River cruise through Cambodia and Vietnam aboard RV Indochine. Explore Siem Reap, Phnom Penh, Chau Doc, Sa Dec, Cai Be, My Tho, and Ho Chi Minh City. Visit temples, markets, pagodas, and local villages while experiencing authentic cultural traditions. Enjoy guided tours, regional flavors, and cultural performances.
Cruise Details
0
Sunset over the Mekong River
from $4,091
EXPLORE

Mekong River - Downstream - High water

Siem Reap to Saigon - 8 Day Itinerary aboard Jayavarman
  • Explore Tonle Lake by boat
  • Visit Kampong Laeang villages
  • Discover Phnom Penh’s history
  • Cross into Vietnam
  • Explore Gieng Island
Starts / Ends
Siem Reap / Ho Chi Minh City
Activities
Cooking Classes, Village Visits, Archaeological Site Visits
Activity Level
Variable
Sail aboard the Jayavarman on an 8-day Mekong River cruise from Siem Reap to Saigon. Explore Cambodia’s Tonle Lake, Phnom Penh’s historic sites, and Vietnam’s colorful Mekong Delta villages while discovering local crafts, culture, and daily river life.
Cruise Details
0
Sunset over the Mekong River
from $4,091
EXPLORE

Mekong River - Downstream - High water

Siem Reap to Saigon - 8 Day Itinerary aboard Jayavarman
  • Aboard a luxury riverboat in Mekong
  • See the floating market in Cai Be
  • Observed locals along the river
  • Visit Tan Chau floating fish farm
  • Visit Phnom Penh cultural sites
Starts / Ends
Siem Reap / Ho Chi Minh City
Activity Level
Variable
Explore the Mekong on this 8-day high-water Mekong River cruise from Siem Reap to Saigon. Get an inside look at the southern cultures of Vietnam and Cambodia as you travel across the mighty Mekong Delta. Stop in charming port towns and immerse yourself in the city's culture and history.
Cruise Details
0
Statues and intricate relief carvings inside Angkor Wat
from $4,125
EXPLORE

From the Angkor Temples to the Mekong Delta

Siem Reap to Ho Chi Minh City - 11 Day Itinerary aboard RV Indochine II
  • Visit Angkor Wat temples
  • Explore Phnom Penh landmarks
  • Visit Cu Chi tunnels in Saigon
  • Discover Koh Chen crafts
Starts / Ends
Siem Reap / Ho Chi Minh City
Activities
Local Market Visits, Land & Sea Exploration
Activity Level
Variable
Embark on an 11-day Mekong River cruise through Vietnam and Cambodia aboard RV Indochine II. Start in Siem Reap with Angkor temples, then sail across Tonle Sap Lake and explore Phnom Penh, Chau Doc, Sa Dec, Cai Be, and Ho Chi Minh City. Visit floating villages, historic landmarks, and cultural sites.
Cruise Details
0
Phnom Penh Royal Palace complex
from $2,111
EXPLORE

Phnom Penh and Siem Reap

Downstream - 4 Day Itinerary aboard RV Bassac Pandaw
  • Sunset cruise on Mekong
  • Explore pottery at Peam Chi Korng
  • Watch silk weaving demonstrations
  • Meditation at Oudong temple
Starts / Ends
Siem Reap / Phnom Penh
Activity Level
Variable
Discover Cambodia on this 4-day cruise aboard RV Bassac Pandaw. Combine the ancient Khmer martial art of Bokator in Silk Island with a visit to Vipassana Dhura Meditation Center in Cambodia's ancient capital, Oudongon, on this expedition across the Tonle and Mekong Rivers.
Cruise Details
0
Royal Palace and Silver Pagoda
from $2,111
EXPLORE

Phnom Penh and Siem Reap

Downstream - 4 Day Itinerary aboard RV Mekong Pandaw
  • Sunset cruise on Mekong
  • Explore pottery at Peam Chi Korng
  • Watch silk weaving demonstrations
  • Meditation at Oudong temple
Starts / Ends
Siem Reap / Phnom Penh
Activity Level
Variable
Discover Cambodia on this 4-day cruise aboard RV Mekong Pandaw. Combine the ancient Khmer martial art of Bokator in Silk Island with a visit to Vipassana Dhura Meditation Center in Cambodia's ancient capital, Oudongon, on this expedition across the Tonle and Mekong Rivers.
Cruise Details
0
Aerial view of Angkor Wat
from $3,675
EXPLORE

From the Mekong Delta to the Angkor Temples

Ho Chin Min City to Angkor - 11 Day Itinerary aboard RV Indochine
  • Visit Ho Chi Minh landmarks
  • Cu Chi tunnels tour
  • Explore Angkor Wat temples
  • Tour Sa Dec historic house
Starts / Ends
Ho Chi Minh City / Siem Reap
Activity Level
Variable
Experience an 11-day Mekong River cruise from Vietnam to Cambodia aboard RV Indochine. Explore Ho Chi Minh City landmarks, My Tho canals, Phnom Penh palaces, and Siem Reap’s Angkor temples. Visit bustling markets, floating villages, craft villages, and historic sites. Discover culture, tradition, and history on a unique river adventure through Southeast Asia.
Cruise Details
0
1-18 of 50 Results

Top Mekong River Travel Destinations

Mekong River Trips by Departure Date

Top Experiences in Mekong River

Mekong River Trips by Duration

Mekong River Trips by Activity

More Reasons

Why Travel With Adventure Life

All News

Recognized By