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Santa Cruz Hotels & Lodging

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Chile

Sherry Ott

What a view of the landscape in Patagonia

Atacama Desert

Augusto Dominguez

Atacama Moon

Easter Island

Explore Easter Island

Cape Horn

Cape Horn Lighthouse and Albatross Monument

Lake District

Banco Imagenes ADS Mundo

Enjoying the incredible landscape on a Chile tour

Magdalena Island

King Penguins in Chile

Puerto Montt

Dora Dalton

Pier at Puerto Montt, Chile

Puerto Varas

Diego Grandi

View of Osorno volcano behind Puerto Varas

Santiago

George Munro

Rivers and Peaks

Torres del Paine

Sherry Ott

Torres del Paine spires

Valparaiso

Road along coastline of Valparaiso

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Build your ideal Chile trip. Call 1.406.541.2677

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Browse our top picks for hotels, lodges, resorts and accommodations in Santa Cruz for 2026-2027. Adventure Life's Santa Cruz travel experts have hand-picked each of the hotels below for their unique local flavor, excellent service, and great base for exploring Santa Cruz. Still can't decide where is the best place to stay in Santa Cruz? No worries, contact one of our Santa Cruz travel experts and they'll help you plan the perfect accommodation and trip to Santa Cruz.

Standard Hotels

Hotel TerraVina

Hotel TerraVina

With the Andes Mountains as the lovely background Hotel TerraViña brings a new concept in Chile: Lodging in a beautiful environment next to an old family winery and dining in elegant surroundings. The hotel boasts of 19 tastefully decorated rooms each with its own balcony with a splendid view.

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The Santa Cruz Plaza pool is beautiful at night

Santa Cruz Plaza

The Santa Cruz Hotel is a traditional colonial-style building located in beautiful Santa Cruz, Chile. The Santa Cruz hotel is nestled in the Colchagua Valley, a world renown wine region. Only 40 km outside of of Santiago, visitors staying in the Santa Cruz Plaza also have easy access to one of Chile's cultural meccas.

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Smart planning. No wasted spend.

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Eric N.

What a view of the landscape in Patagonia — Chile

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Mount Gahinga National Park - Golden Monkey trekking

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