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Palermo Italy Cruises

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Experience the alluring charm of Palermo with Adventure Life's selection of 9 captivating Cruises for 2025. Join us on a cruise journey through this vibrant city, known for its rich history, stunning architecture, and delicious cuisine. From exploring archaeological sites to indulging in wine tasting experiences, every moment offers a unique opportunity to immerse yourself in the cultural tapestry of Palermo. Engage in urban exploration, local market visits, and photography seminars as you navigate through this Mediterranean gem. With activities ranging from food & wine tours to wildlife viewing, there is something for every traveler to enjoy in Palermo. Don't miss the chance to embark on a journey filled with adventure and discovery in this captivating Italian city. Contact one of Adventure Life's tour specialists for help planning your next seamless trip.
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    • Palermo
Sunset over Palermo
from $3,799
2for1
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Sicilian Sunsets & Amalfi Delights

Malta - Naples - 8 Day Itinerary aboard Variety Voyager
Starts / Ends
Valletta / Naples
Activity Level
Variable
Embark on an 8-day cruise aboard the Variety Voyager from Valletta to Sicily and Southern Italy, exploring historic cities and stunning coastlines. Discover Agrigento, Erice, and Pompeii while enjoying exclusive onboard experiences and authentic Sicilian cuisine.
  • Explore Agrigento’s Temple Valley
  • Marvel at Trapani’s medieval street
  • Discover Erice’s Venus Castle
  • Taste Palermo’s food delights
Cruise Details
0
Explore historic Bonifacio atop the cliffs of Corsica
from $7,790
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Mediterranean Island Voyage: Sicily, Sardinia, Corsica, and Elba – with Smithsonian Journeys

Valletta - Nice - 8 Day Itinerary aboard Le Bougainville
Starts / Ends
Valletta / Nice
Activities
Land & Sea Exploration
Activity Level
Variable
Explore the heart of the Mediterranean on this 8-day Mediterranean Island Cruise with Smithsonian Journeys from Valletta to Nice aboard Le Bougainville. Discover Sicily, Sardinia, Corsica, and Elba's historical civilizations that left mark on these islands' language, cuisine, art, and architecture.
  • Discover Mediterranean islands
  • Experience ancient ruins
  • Admire Byzantine-Arab mosaics
  • Explore medieval towns
  • Discover local cuisine
Cruise Details
0
Tour the charming city of Valletta, Malta.
from $9,450
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A Circumnavigation of Sicily with Smithsonian Journeys

Valletta - Valletta - 9 Day Itinerary aboard Le Bougainville
Starts / Ends
Valletta / Valletta
Activity Level
Variable
During this 9-day cruise around Sicily aboard the new luxury expedition ship Le Bougainville, you'll be able to explore mythical places at the crossroads of Eastern and Western civilizations. Discover Sicily's most beautiful historic cities and ancient sites.
  • Take a loop around Sicily
  • Discover Sicily's beautiful cities
  • Visit Syracuse
  • Explore Palermo
Cruise Details
0
Relax in beautiful Sicily
from $8,490
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Longing for La Dolce Vita

Sicily - Italy - 8 Day Itinerary aboard Sea Cloud Spirit
Starts / Ends
Catania / Naples
Activity Level
Variable
Embark on an 8-day "Longing for La Dolce Vita" cruise aboard the Sea Cloud Spirit. Begin in Taormina, a town known for its blend of cultures and varied cuisine. Explore Palermo and discover its historic palazzi and gold mosaics, then head to Lipari, an island with volcanic landscapes and a lively harbor town. The trip concludes in Amalfi.
  • Visit Taormina
  • Discover Palermo
  • Explore Lipari
  • Explore Amalfi
Cruise Details
0
Explore ruins in Sicily
from $5,840
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Cruising the Mediterranean: Sicily, Sardinia, and Mallorca – with Smithsonian Journeys

Valletta - Barcelona - 8 Day Itinerary aboard Le Boreal
Starts / Ends
Valletta / Tarragona
Activities
Local Market Visits
Activity Level
Variable
Embark on an 8-day Le Boreal cruise from Valletta to Barcelona. Visit Sicily’s historic cities, Sardinia’s archaeological treasures, and the Balearic Islands’ stunning landscapes. Shore excursions, transfers, and expert-led discussions with Smithsonian Journeys.
  • Visit UNESCO sites in Valletta
  • Indulge in Sicilian seafood
  • Stroll Mahon's colorful streets
  • Transit the Corinth Canal passage
Cruise Details
0
Explore ruins in Sicily
from $6,330
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Cruising the Mediterranean: Sicily, Sardinia, and Mallorca – with Smithsonian Journeys

Valletta - Tarragona - 8 Day Itinerary aboard L'Austral
Starts / Ends
Valletta / Tarragona
Activity Level
Variable
Experience an 8-day cruise aboard L'Austral, exploring cultural treasures in the Mediterranean's historic ports. From UNESCO-listed Valletta to the Roman ruins of Tarragona, delve into the region's rich heritage and scenic beauty.
  • Visit UNESCO charm in Valletta
  • Explore Tarragona's Roman ruins
  • Indulge in Sicilian seafood
  • Stroll Mahon's colorful streets
Cruise Details
0
from $9,540
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Culture and Islands of the Mediterranean

Barcelona - Valletta - 12 Day Itinerary aboard L'Austral
Starts / Ends
Barcelona / Valletta
Activities
Urban Exploration
Activity Level
Variable
Embark on a 12-day cruise from Barcelona to Malta aboard L’Austral. Enjoy culinary and cultural experiences with an included excursion per port. Highlights include Menorca, Alghero, Cagliari, Trapani, Palermo, Lipari, Catania, Syracuse, Gozo, and ending in Valletta.
  • Visit Menorca
  • Explore Sardinia
  • Discover Sicily
  • Experience Catania
  • Discover Syracuse
  • Discover Malta
Cruise Details
0
Visit Rome's famed Colosseum
from $12,795
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The Amalfi, Sicily and Malta: The Godfather

Rome - Valletta - 12 Day Itinerary aboard Douglas Mawson
Starts / Ends
Rome / Valletta
Activities
Wine Tasting, Small Ship Sailing
Activity Level
Variable
Join this 12-day cruise on the Douglas Mawson, exploring Southern Italy, Sicily, and Malta's stunning history and culture. Experience the Amalfi Coast, ancient cities, and Malta's heritage while savoring local cuisine and vibrant Mediterranean life.
  • Discover Rome’s imperial relics
  • Explore Gaeta’s medieval fortress
  • Wander Naples’ ancient streets
  • Marvel at Pompeii’s ruins
Cruise Details
0
Relax in beautiful Sicily
from $8,370
EXPLORE

A Circumnavigation of Sicily with Smithsonian Journeys

Valletta Roundtrip - 9 Day Itinerary aboard Le Dumont-d'Urville
Starts / Ends
Valletta / Valletta
Activities
Archaeological Site Visits, Village Visits
Activity Level
Variable
Set sail on a 9-day Sicily cruise aboard Le Dumont-d'Urville. Visit UNESCO sites like Valletta and the Valley of Temples, admire Stromboli’s volcanic activity, explore vibrant cities such as Palermo and Syracuse, and discover ancient ruins, diverse cultures, and beautiful coastal views.
  • Visit Valleta a UNESCO-listed city
  • Visit Valley of Temples
  • Witness a fiery volcano
  • Discover Trapani's diverse heritage
Cruise Details
0
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