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Palermo

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Trevi Fountain in Rome
Sicily
Balate Dorin
Visit charming Sicily
Lipari
Roman Babakin
Hiking on the Amalfi coast overlooking the Tyrrhenian sea
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Select one of the below 13 best Palermo trips for 2026 and 2027. Your local English-speaking guide will lead your small group or personalized private tour on an extraordinary adventure exploring Palermo. Our Palermo trips for 2026 feature Archaeological Site Visits, Village Visits, Local Market Visits, Urban Exploration, and Wine Tasting, and start from $3,350 for trips of 8 to 13 days. Contact Adventure Life's Palermo trip planning experts to start planning your next seamless trip.

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    • Palermo
Relax in beautiful Sicily
from $3,390
EXPLORE

Sicilian Sunsets & Amalfi Delights

Malta - Naples - 8 Day Itinerary aboard Variety Voyager
  • Explore Agrigento’s Temple Valley
  • Marvel at Trapani’s medieval street
  • Discover Erice’s Venus Castle
  • Taste Palermo’s food delights
Starts / Ends
Valletta / Naples
Activity Level
Variable
Embark on an 8-day cruise aboard the Variety Voyager from Valletta to Sicily and Southern Italy, exploring historic cities and stunning coastlines. Discover Agrigento, Erice, and Pompeii while enjoying exclusive onboard experiences and authentic Sicilian cuisine.
Cruise Details
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Visit charming Sicily
from $3,420
EXPLORE

Highlights of Sicily

Italy Small Group Tour - 9 Day Itinerary
  • Visit the Island of Sicily
  • Discover the Valley of the Temples
  • Visit Taormina's ancient ruins
  • See the Mount Etna in Sicily
  • Explore the coastal town of Cefalu
  • Visit Syracuse's Archeological Park
  • Discover the Zingaro Nature Reserve
Starts / Ends
Viagrande / Taormina
Activities
Hiking
Activity Level
Relaxed
Spend 9 days on this small group journey through the highlights of Sicily to step into a world where ancient ruins stand alongside vibrant cities and picturesque landscapes. Discover ancient ruins, bask in the island's natural beauty, and indulge in Sicily's culinary delights.
Tour Details
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Ruins of Greece
from $7,790
EXPLORE

Cruising the Mediterranean: Sicily, Sardinia, and Mallorca – with Smithsonian Journeys

Valletta - Barcelona - 8 Day Itinerary aboard Le Boreal
  • Visit UNESCO sites in Valletta
  • Indulge in Sicilian seafood
  • Stroll Mahon's colorful streets
  • Transit the Corinth Canal passage
Starts / Ends
Valletta / Tarragona
Activity Level
Variable
Embark on an 8-day Le Boreal cruise from Valletta to Barcelona. Visit Sicily’s historic cities, Sardinia’s archaeological treasures, and the Balearic Islands’ stunning landscapes. Shore excursions, transfers, and expert-led discussions with Smithsonian Journeys.
Cruise Details
0
Beautiful Taormina, Italy, with Mt. Etna in the background
from $7,750
EXPLORE

Mediterranean Island Voyage: Sicily, Sardinia, Corsica, and Elba – with Smithsonian Journeys

Nice - Valletta - 8 Day Itinerary aboard Le Dumont-d'Urville
  • Wander Nice Cours Saleya markets
  • Discover Bonifacio limestone cliffs
  • Tour Cagliari old ramparts
  • See Valletta Barrakka Gardens
Starts / Ends
Nice / Valletta
Activity Level
Variable
Set sail on an 8-day Mediterranean cruise aboard Le Dumont-d'Urville, visiting Napoleon's residence in Portoferraio, the medieval streets of Bonifacio, and the vibrant markets of Palermo. Conclude your journey in Valletta, Malta, exploring the Grandmaster's Palace and St. John's Cathedral.
Cruise Details
0
The rocky cliffs of Calabria, Italy
from $8,510
EXPLORE

Authentic Mediterranean Shores

Valletta Roundtrip - 10 Day Itinerary aboard Le Boreal
  • Walk Valletta’s historic streets
  • Visit Palermo’s Palatine Chapel
  • Discover Lipari’s volcanic cliffs
  • Explore Trapani’s cultural sites
Starts / Ends
Valletta / Valletta
Activity Level
Variable
Embark in Valletta for a 10-day Mediterranean cruise to Sicily and southern Italy aboard Le Boreal. Explore Syracuse, Palermo, Lipari, Taormina, and Pompeii. Visit temples, amphitheaters, cathedrals, and volcanic sites. Enjoy views of Stromboli and Etna, then return to Malta aboard a luxury ship with cultural programming and refined comfort.
Cruise Details
0
Sunset over Palermo
from $9,120
EXPLORE

Mediterranean Island Voyage: Sicily, Sardinia, Corsica, and Elba – with Smithsonian Journeys

Valletta - Nice - 9 Day Itinerary aboard Le Dumont-d'Urville
  • Explore Valletta Barrakka Gardens
  • Discover Gozo temples of Ggantija
  • Tour Taormina Greco-Roman theater
  • See Cagliari old ramparts
Starts / Ends
Valletta / Nice
Activity Level
Variable
Experience a 9-day Mediterranean cruise on the Le Dumont-d'Urville, exploring historic sites in Malta, Sicily, and Sardinia. Conclude your cruise in Nice after visiting picturesque landscapes and cultural landmarks throughout the region.
Cruise Details
0
Visit Rome's famed Colosseum
from $12,795
EBD
EXPLORE

The Amalfi, Sicily and Malta: The Godfather

Rome - Valletta - 12 Day Itinerary aboard MV Douglas Mawson
  • Discover Rome’s imperial relics
  • Explore Gaeta’s medieval fortress
  • Wander Naples’ ancient streets
  • Marvel at Pompeii’s ruins
Starts / Ends
Rome / Valletta
Activity Level
Variable
Join this 12-day cruise on the Douglas Mawson, exploring Southern Italy, Sicily, and Malta's stunning history and culture. Experience the Amalfi Coast, ancient cities, and Malta's heritage while savoring local cuisine and vibrant Mediterranean life.
Cruise Details
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Mount Etna looms over an ancient town
from $14,595
EBD
EXPLORE

The Amalfi, Sicily and Malta: The Godfather

Rome - Valletta - 13 Day Itinerary aboard MV Douglas Mawson
  • Explore Rome to view the Colosseum
  • Explore Gaeta monastery site
  • Sail the Amalfi Coast
  • Wander Agrigento and Greek ruins
Starts / Ends
Rome / Valletta
Activities
Wine Tasting
Activity Level
Variable
Embark on a 13-day Mediterranean cruise aboard the Douglas Mawson, exploring Sicily, Malta, and the stunning Amalfi Coast. Experience ancient architecture, rich histories, and the region's famous cuisine amidst scenic coastal landscapes.
Cruise Details
0
Explore Agropoli, Italy
from $3,350
EXPLORE

Sicily Unveiled with Italian Treasures

Roundtrip Civitavecchia - 11 Day Itinerary aboard Star Clipper
  • Sail coastlines of Sicily
  • Cruise Aeolian Islands
  • Visit Trapani port
  • Explore Palermo streets
Starts / Ends
Civitavecchia / Civitavecchia
Activities
Small Ship Sailing
Activity Level
Variable
Sail Italy’s southern coast on an 11-day cruise aboard Star Clipper. Experience Sicily, the Aeolian Islands, Calabria, and the Amalfi Coast, navigating volcanic landscapes, historic ports, and small island harbors for an intimate sailing experience.
Cruise Details
0
Enjoy stunning sunset views over Zadar
from $17,795
Save $150
EXPLORE

Adriatic, Sicily & the Amalfi Coast

Civitavecchia - Venice - 12 Day Itinerary aboard Scenic Ikon
  • Explore Rome elaborate churches
  • Discover Capri Piazzetta
  • See Lipari pastel townhouses
  • Experience Palermo arancini
Starts / Ends
Civitavecchia / Venice
Activities
Village Visits, Archaeological Site Visits, Urban Exploration, Local Market Visits
Activity Level
Variable
Set sail on a 12-day cruise from Civitavecchia, exploring Rome, Sicily, and the Amalfi Coast. Experience luxury aboard the Scenic Ikon while tasting Mediterranean cuisine and discovering unique cultures in breathtaking destinations.
Cruise Details
0
from $9,540
EXPLORE

Culture and Islands of the Mediterranean

Barcelona - Valletta - 12 Day Itinerary aboard L'Austral
  • Visit Menorca
  • Explore Sardinia
  • Discover Sicily
  • Experience Catania
  • Discover Syracuse
  • Discover Malta
Starts / Ends
Barcelona / Valletta
Activity Level
Variable
Embark on a 12-day cruise from Barcelona to Malta aboard L’Austral. Enjoy culinary and cultural experiences with an included excursion per port. Highlights include Menorca, Alghero, Cagliari, Trapani, Palermo, Lipari, Catania, Syracuse, Gozo, and ending in Valletta.
Cruise Details
0
Relax in beautiful Sicily
from $9,490
EXPLORE

A Circumnavigation of Sicily with Smithsonian Journeys

Valletta Roundtrip - 9 Day Itinerary aboard Le Dumont-d'Urville
  • Visit Valleta a UNESCO-listed city
  • Visit Valley of Temples
  • Witness a fiery volcano
  • Discover Trapani's diverse heritage
Starts / Ends
Valletta / Valletta
Activity Level
Variable
Set sail on a 9-day Sicily cruise aboard Le Dumont-d'Urville. Visit UNESCO sites like Valletta and the Valley of Temples, admire Stromboli’s volcanic activity, explore vibrant cities such as Palermo and Syracuse, and discover ancient ruins, diverse cultures, and beautiful coastal views.
Cruise Details
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