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Coast of Ortigia island at city of Syracuse

Syracuse Cultural Cruises

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Explore the captivating cultural wonders of Syracuse, Sicily, with Adventure Life's array of tours for 2026. Join us on a trip that delves deep into the heart of this historic city, where ancient civilizations have left their mark on ornate cathedrals, baroque buildings, and archaeological sites like Pompeii and the Greek temples of Paestum. Meander through charming clifftop towns, marvel at breathtaking views, and soak up the Mediterranean charm of the Amalfi Coast. With activities ranging from village visits to small ship cruises, this journey promises a relaxed exploration of the treasures of Syracuse. Don't miss the chance to witness the rich history and beauty of this Mediterranean gem. Contact one of Adventure Life's tour specialists for help planning your next seamless trip.
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Naples at Sunset, Italy
from $3,390
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La Dolce Vita

Naples - Malta - 8 Day Itinerary aboard Variety Voyager
  • Explore Capri's coastal allure
  • Visit Lipari’s ancient sites
  • Discover Taormina’s historic alleys
  • Wander Syracuse’s ancient streets
Starts / Ends
Naples / Valletta
Activity Level
Variable
Embark on an 8-day cruise aboard the Variety Voyager from Naples to Malta, visiting Capri, Taormina, Mount Etna, and Catania in Sicily. In Malta, explore Valletta's UNESCO sites and Gozo's ancient monuments.
Cruise Details
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Explore ruins in Taormina within view of volcanic Mount Etna
from $3,899
EXPLORE

Volcanoes of Italy

Naples - Malta - 8 Day Itinerary aboard Variety Voyager
  • Discover Lipari Aeolian archipelago
  • Explore Gozo Ggantija monuments
  • Wander Taormina Greek amphitheater
  • Savor Catania local wines
Starts / Ends
Naples / Valletta
Activities
Village Visits, Wine Tasting
Activity Level
Variable
Join an 8-day cruise from Naples to Valletta aboard the Variety Voyager, guided by National Geographic Explorer George Kourounis. Explore Capri, Sicily's Taormina and Mount Etna, and Malta's UNESCO sites, while attending lectures on the region's geology.
Cruise Details
0
Athens Acropolis
from $1,740
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Sicily & Greece

Piraeus - Valletta - 6 Day Itinerary aboard Star Clipper
  • Explore Athens ancient Agora
  • Walk Monemvasia twisting alleys
  • Wander Syracuse baroque piazzas
  • Discover Valletta capital
Starts / Ends
Piraeus / Valletta
Activities
Small Ship Sailing
Activity Level
Variable
Embark on a 6-day Mediterranean cruise from Piraeus to Valletta aboard the Star Clipper, visiting historic sites in Greece, Italy, and Malta. Highlights include Monemvasia, Pilos, and Syracuse, concluding in Valletta, a UNESCO World Heritage site.
Cruise Details
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Explore the ancient Acropolis
from $2,290
SS 25%
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Sicily & Greece

Piraeus - Valletta - 7 Day Itinerary aboard Royal Clipper
  • Wander Athens Ancient Agora
  • Explore Pylos Navarino Bay
  • Explore Syracuse’s historical ruins
  • Visit Valletta’s museums palaces
Starts / Ends
Piraeus / Valletta
Activity Level
Variable
Set sail on a 7-day Mediterranean cruise from Piraeus to Valletta aboard the Royal Clipper, exploring historic Athens, Monemvasia's Byzantine fortress, and Pylos, famous for King Nestor’s Palace. Discover Sicily's Syracuse and Malta's Gozo, known for diving and coastal caves, before concluding in the fortified capital of Valletta.
Cruise Details
0
Beautiful Taormina, Italy, with Mt. Etna in the background
from $7,750
EXPLORE

Mediterranean Island Voyage: Sicily, Sardinia, Corsica, and Elba – with Smithsonian Journeys

Nice - Valletta - 8 Day Itinerary aboard Le Dumont-d'Urville
  • Wander Nice Cours Saleya markets
  • Discover Bonifacio limestone cliffs
  • Tour Cagliari old ramparts
  • See Valletta Barrakka Gardens
Starts / Ends
Nice / Valletta
Activities
Archaeological Site Visits, Local Market Visits, Urban Exploration
Activity Level
Variable
Set sail on an 8-day Mediterranean cruise aboard Le Dumont-d'Urville, visiting Napoleon's residence in Portoferraio, the medieval streets of Bonifacio, and the vibrant markets of Palermo. Conclude your journey in Valletta, Malta, exploring the Grandmaster's Palace and St. John's Cathedral.
Cruise Details
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Stroll the ancient walkways of Athens
from $6,590
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Ancient Cities of the Mediterranean

Athens - Valletta - 8 Day Itinerary aboard Le Dumont-d'Urville
  • Explore ancient Athens landmarks
  • Walk Nafplion’s fortress paths
  • Discover Corfu’s old town
  • Tour Valletta’s historic streets
Starts / Ends
Athens / Valletta
Activity Level
Variable
Sail from Athens to Valletta on an 8-day cruise aboard Le Dumont-d’Urville. Visit Nafplion, Monemvasia, Gythio, Corfu, Gallipoli, and Syracuse. From ancient fortresses and neoclassical towns to volcanic coasts and baroque streets, explore the deep cultural heritage of Greece, Italy, and Malta along the Ionian and Aegean seas.
Cruise Details
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Coast of Ortigia island at city of Syracuse
from $3,195
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The Best of the Mediterranean

Roundtrip Valletta - 8 Day Itinerary aboard MV La Belle de L'Adriatique
  • Explore Saint John's Baroque
  • Taste chocolate in Modica
  • Ascend mighty Mount Etna
  • Stroll Mdina’s medieval streets
Starts / Ends
Valletta / Valletta
Activity Level
Variable
Discover the best of the Mediterranean as you explore the magic of Malta and Sicily on an 8-day cruise aboard La Belle de l’Adriatique, featuring UNESCO sites, historic towns, and local flavors. From Valletta to Syracuse, enjoy every excursions, cultural treasures, and vibrant onboard festivities.
Cruise Details
0
Athens Acropolis
from $2,820
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Sicily & Greece

Piraeus - Valletta - 9 Day Itinerary aboard Star Flyer
  • Explore Milos Sarakiniko Bay
  • Visit Chania Venetian harbor
  • Walk Gythio streets
  • Explore Valletta the walled city
Starts / Ends
Piraeus / Valletta
Activity Level
Variable
Experience a 9-day Mediterranean sailing cruise on the Star Flyer, exploring ancient Athens, stunning Milos, and the charming alleys of Chania. Visit historic sites in Gythio, Pylos, Syracuse, Gozo, and end in Valletta, famous for its fortified city and gardens.
Cruise Details
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A stunning view of Nafplion, Greece
from $2,150
SS 25%
EXPLORE

Sicily & Greece

Valletta to Athens - 7 Day Itinerary aboard Star Flyer
  • Explore Valletta the walled city
  • Explore Syracuse ruins
  • Visit Pilos Navarino Bay
  • Stroll Nafplio waterfront
Starts / Ends
Valletta / Piraeus
Activity Level
Variable
Join a 7-day cruise from Valletta to Piraeus on the Star Flyer, exploring historic sites like Syracuse's archaeological park and Monemvasia's Byzantine fortress. Visit Nafplio's Venetian architecture before concluding in Piraeus, where you can explore Athens' Acropolis and Agora.
Cruise Details
0
The rocky cliffs of Calabria, Italy
from $8,510
EXPLORE

Authentic Mediterranean Shores

Valletta Roundtrip - 10 Day Itinerary aboard Le Boreal
  • Walk Valletta’s historic streets
  • Visit Palermo’s Palatine Chapel
  • Discover Lipari’s volcanic cliffs
  • Explore Trapani’s cultural sites
Starts / Ends
Valletta / Valletta
Activity Level
Variable
Embark in Valletta for a 10-day Mediterranean cruise to Sicily and southern Italy aboard Le Boreal. Explore Syracuse, Palermo, Lipari, Taormina, and Pompeii. Visit temples, amphitheaters, cathedrals, and volcanic sites. Enjoy views of Stromboli and Etna, then return to Malta aboard a luxury ship with cultural programming and refined comfort.
Cruise Details
0
Sunset over Palermo
from $9,120
EXPLORE

Mediterranean Island Voyage: Sicily, Sardinia, Corsica, and Elba – with Smithsonian Journeys

Valletta - Nice - 9 Day Itinerary aboard Le Dumont-d'Urville
  • Explore Valletta Barrakka Gardens
  • Discover Gozo temples of Ggantija
  • Tour Taormina Greco-Roman theater
  • See Cagliari old ramparts
Starts / Ends
Valletta / Nice
Activity Level
Variable
Experience a 9-day Mediterranean cruise on the Le Dumont-d'Urville, exploring historic sites in Malta, Sicily, and Sardinia. Conclude your cruise in Nice after visiting picturesque landscapes and cultural landmarks throughout the region.
Cruise Details
0
Visit Rome's famed Colosseum
from $12,795
EBD
EXPLORE

The Amalfi, Sicily and Malta: The Godfather

Rome - Valletta - 12 Day Itinerary aboard MV Douglas Mawson
  • Discover Rome’s imperial relics
  • Explore Gaeta’s medieval fortress
  • Wander Naples’ ancient streets
  • Marvel at Pompeii’s ruins
Starts / Ends
Rome / Valletta
Activity Level
Variable
Join this 12-day cruise on the Douglas Mawson, exploring Southern Italy, Sicily, and Malta's stunning history and culture. Experience the Amalfi Coast, ancient cities, and Malta's heritage while savoring local cuisine and vibrant Mediterranean life.
Cruise Details
0
1-12 of 25 Results

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Wander the ancient stones of Syracuse, one of the most prestigious cities of the Helenistic world
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