Have questions? We're here.
Playful sea lions

South America Cruises

Travel made your way ™
Talk with an expert
Build your ideal South America trip. Call 800.344.6118
Start Planning My Trip
Filter (559 Results)
  • Start Date
    Months
    Years
  • Length
    to
  • Price
    to
  • Activity Levels
  • Experiences
  • Activities
  • Ships
  • Destinations
    • South America
Nights in Ushuaia
from $22,317
Save 5%
EXPLORE

Antarctica and Patagonia: Legendary Ice and Epic Fjords

Northbound - 18 Day Itinerary aboard National Geographic Explorer
  • Seek iconic animals of Antarctica
  • Marvel at magnificent icebergs
  • Hike Torres del Paine National Park
  • Explore Francisco Coloane Marine
Starts / Ends
The Ritz-Carlton, Santiago / Puerto Natales
Activity Level
Variable
Explore mythical landscapes in Patagonia and Antarctica. Spend 18 days observing unique wildlife, saw-toothed mountains, deep fjords, and vivid blue glaciers onboard the National Geographic Explorer. Observe breaching humpback whales and penguin colonies. 
Cruise Details
0
Beautiful Galapagos landscape
from $10,000
EXPLORE

Islands Circumnavigation

15 Day Itinerary aboard Samba
  • See sea lions on Mosquera
  • Explore in the Mangrove forest
  • Enjoy a volcanic Olivine beach
  • Take incredible photos of landscape
Activities
Small Ship Sailing
Activity Level
Variable
Enjoy 15 days of relaxing and fun aboard Samba yacht! Visit Santa Cruz, Floreana, Española, San Cristobal, Santa Fe, Santiago, Bartholomew, Rabida and North Seymour. Discover the magnificent wildlife and the incredible landscapes on Galapagos Islands .
Cruise Details
0
Puerto Natales, Patagonia
from $36,157
Save 5%
EXPLORE

Antarctica and Patagonia: Legendary Ice and Epic Fjords

Ushuaia to Puerto Natales - 17 Day Itinerary aboard National Geographic Resolution
  • Chilean fjords glacier sailing
  • Torres del Paine discovery
  • Francisco Coloane whale watching
  • Kayak near Antarctica’s landscapes
Starts / Ends
Santiago / Santiago
Activities
Archaeological Site Visits
Activity Level
Variable
Explore Antarctica and southern Chile on an 17-day cruise aboard National Geographic Resolution. Cruise from Ushuaia across the Drake Passage into Antarctica’s icy wilderness. Navigate through towering glaciers, remote fjords, and protected marine parks. Experience exploration through narrow channels inaccessible to larger vessels.
Cruise Details
0
Whale bones at the Grytviken whaling station
from $16,136
EXPLORE

South Georgia & Falklands From Punta Arenas to Montevideo

Santiago - Montevideo - 18 Day Itinerary aboard MS Fram
  • Sail toward South Georgia
  • Visit historic Grytviken
  • Explore Falkland Islands
  • Watch migrating whales
Starts / Ends
Santiago / Montevideo
Activities
Citizen Science
Activity Level
Variable
Embark on an 18-day expedition aboard MS Fram from Santiago to Montevideo via South Georgia and the Falkland Islands. Encounter remarkable wildlife, explore remote landscapes, and enjoy immersive expedition experiences guided by expert naturalists.
Cruise Details
0
The Amazon River
from $11,680
EXPLORE

Luxury Amazon Expeditions Cruise - High Water

Roundtrip Iquitos - 8 Day Itinerary aboard Aqua Nera
  • Discover Iquitos cuisine
  • Spot Yanayacu Yacapana wildlife
  • Learn about Amazon fierce piranhas
  • Visit Clavero Lake villagers
Starts / Ends
Iquitos / Iquitos
Activities
Village Visits, Local Market Visits
Activity Level
Variable
Embark on an 8-day Amazon River cruise on the Aqua Nera, starting with a warm welcome and local cuisine in Iquitos. Explore rivers, wildlife, artisan markets, and conservation efforts, concluding your journey with a visit to the Manatee Rescue Center.
Cruise Details
0
A pair of friendly sea lions
from $9,445
Savings
EXPLORE

Island Circumnavigation

8 Day Itinerary aboard Galapagos Horizon
  • Discover Sullivan Bay's beauty
  • Observe mola-mola sunfish
  • Swim & snorel across Isabela Island
  • Visit South Plaza Islands
Starts / Ends
Baltra / San Cristobal Airport
Activities
Hiking, Snorkeling
Activity Level
Variable
This 8-day cruise offers incredible snorkeling, hiking, and kayaking adventures all around the Galapagos archipelago in style. Gourmet cuisine, the best guides, and spacious & stylish cabins guarantee a top-notch luxury cruising experience second to none.
Cruise Details
0
Spot the Three Toed Sloth
from $6,700
EXPLORE

Amazon Encounter - Low Water Season

Nauta - Iquitos - 5 Day Itinerary aboard Delfin Amazon Cruises
  • Explore the Marañón River
  • Spot pink river dolphins
  • Meet a revered shaman
  • Kayak through the rainforest
  • Walk the Fundo Casual trail
Starts / Ends
Iquitos / Iquitos
Activities
Stand Up Paddle Boarding
Activity Level
Variable
Take a 5-day Amazon River cruise in Peru aboard the Delfin I. Travel from Iquitos to Nauta, Yanayacu, Yarapa, and the Amazon Confluence. Explore wildlife, meet local communities, and uncover rainforest traditions. Enjoy skiff rides, kayaking, piranha fishing, and cultural encounters while experiencing the heart of the Peruvian Amazon.
Cruise Details
0
baby sloth... oh so soft
from $6,600
EXPLORE

Amazon Encounter - High Water Season

Nauta - Iquitos - 5 Day Itinerary aboard Delfin III
  • Marañón River skiff exploration
  • Dorado River kayak experience
  • Amazon tributary confluence views
  • Fundo Casual rainforest walk
  • Pacaya River full exploration
Starts / Ends
Iquitos / Iquitos
Activities
Rainforest Exploration, Fishing
Activity Level
Variable
Embark on a 5-day Peruvian Amazon cruise from Iquitos to Nauta aboard the Delfin III. Cruise rivers, spot wildlife, kayak flooded forests, and visit riverside communities inside Pacaya Samiria National Reserve. Experience guided excursions, cultural insights, and unique rainforest ecosystems.
Cruise Details
0
Kayaking Tagus Cove
from $5,000
EXPLORE

Northwest Islands

8 Day Itinerary aboard Samba
  • See sea lions on Mosquera
  • Observe the nesting of boobies
  • Explore in the Mangrove forest
  • Hiking and observe the twin craters
Starts / Ends
Baltra / Baltra
Activity Level
Variable
Explore 8 days of relaxing and fun aboard Samba yacht! Visit Genovesa, Isabela, Marchena, Fernandina, Floreana, Santa Cruz. Discover wildlife and the incredible landscapes of the Galapagos Islands!
Cruise Details
0
An old ship rusts in a Falkland Islands harbor
from $15,995
EXPLORE

Falklands (Malvinas) & South Georgia

Punta Arenas Roundtrip - 17 Day Itinerary aboard Magellan Discoverer
  • Encounter King Penguin Colonies
  • View Historic Grytviken Settlement
  • Cruise Drygalski Fjord Glaciers
  • Walk Port Stanley Waterfront
Starts / Ends
Punta Arenas / Punta Arenas
Activity Level
Variable
Sail 17 days roundtrip from Punta Arenas to the Falklands and South Georgia aboard Magellan Discoverer. Encounter king penguins at St Andrews Bay, walk in Shackleton’s footsteps at Grytviken, and cruise Drygalski Fjord. Explore Port Stanley, Bleaker Island, and Salisbury Plain while attending expert lectures at sea.
Cruise Details
0
Bird perched in the Amazon rainforest
from $1,582
EXPLORE

Amazon Journey

Iquitos to Nauta - 4 Day Itinerary aboard La Perla
  • Visit Pacaya Samiria National Reser
  • Admire the incredible wildlife
  • Learn more about the Amazon culture
Starts / Ends
Iquitos / Nauta
Activity Level
Variable
This 4-day Amazon cruise of Iquitos & Nauta aboard La Perla gives you an insider's view of life in Peru's rainforest, including piranha fishing, wildlife spotting, visit local villages, and opportunities to learn about wildlife preservation!
Cruise Details
0
King penguins on South Georgia
from $13,670
EXPLORE

Into the Wild South: The Falklands, South Georgia & Antarctica

Montevideo - Ushuaia - 21 Day Itinerary aboard Terra Nova Adventurer
  • Explore South Georgia's history
  • See South Georgia Wildlife
  • Cross the Scotia Sea
  • Explore Antarctica by Zodiac
Starts / Ends
Montevideo / Port of Ushuaia
Activities
Wildlife Viewing, Kayaking, Whale Watching, Camping, Photography Seminars
Activity Level
Variable
Sail on a 21-day expedition from Montevideo to Ushuaia aboard Terra Nova Adventurer, exploring the Falkland Islands, South Georgia and early-season Antarctica. Watch albatrosses, petrels, whales and penguins, explore remote shores by Zodiac and on foot, and encounter landscapes shaped by exploration, wildlife and changing polar conditions.
Cruise Details
0
373-384 of 559 Results

Plan smarter. Spend better.

Talk with an expert trip planner 800.344.6118

Plan My Trip
Jason Maynard employee profile
Jason M.
Peruvian weavers
South America

Chat South America with a specialist

Our team is waiting and ready to talk with you about your next adventure. So go ahead and book an appointment with one of our specialized trip planners.

Let's Chat
800.344.6118

Where is your next adventure?

Contact Chat Call

Why Travel With Us?

Seamless Trip Planning

We guide you through every detail beyond the cruise—from flights to pre- and post-trip stays—so your journey feels effortless.

Rewards That Go Further

Secure your 5% Past Traveler Rewards across a wide range of ships and destinations - not a single brand and not just cruises.

Unbiased Cruise Expertise

We're not tied to any one cruise line, so you receive honest guidance on the best ship and itinerary for you—not a sales pitch.

As Featured In

How it Works

Connect

No cost, no commitment. Talk with our experts about your dream trip.

Plan

Share your travel style—we match you with the right itinerary or create one just for you.

Book

Lock in knowing every detail is handled and you’re fully supported.

Travel

Enjoy a seamless journey—and unlock 5% off your next adventure.