Have questions? We're here.
Playful sea lions

South America Cruises

Travel made your way
Talk with an expert
Build your ideal South America trip. Call 1.406.541.2677
Start Planning My Trip
Filter (563 Results)
  • Start Date
    OR, More specific start
  • Length
    to
  • Price
    to
  • Activity Levels
  • Experiences
  • Activities
  • Ships
  • Destinations
    • South America
1800's whaling station
from $32,295
EBD
EXPLORE

South Georgia, Falklands & Antarctic Odyssey

Ushuaia - Punta Arenas - 20 Day Itinerary aboard Sylvia Earle
  • Discover Falklands’ beaches
  • Marvel at South Georgia’s glaciers
  • Spot Antarctica's wildlife
  • Explore Ushuaia’s rugged landscapes
Starts / Ends
Port of Ushuaia / Punta Arenas
Activities
Snorkeling, Scuba Diving
Activity Level
Variable
Join a 20-day cruise on the Sylvia Earle, exploring Ushuaia, the Falklands, South Georgia, and Antarctica. Experience stunning landscapes, diverse wildlife, and expert-led activities, concluding with a flight from King George Island to Punta Arenas.
Cruise Details
0
Pink dolphin
from $3,016
EXPLORE

Amazon Exploration: Search for the Pink Dolphin

5 Day Itinerary aboard Manatee
  • Search for the pink river dolphin
  • Visit a school on the Napo River
  • Climb a 100-foot observation tower
Activities
Village Visits
Activity Level
Variable
This 5-day itinerary on the Manatee is designed to highlight the incredible biodiversity, wildlife, and natural beauty found in the Amazon.
Cruise Details
0
Pink dolphin in the Amazon
from $1,400
EXPLORE

Amazon Journey

Nauta Roundtrip - 4 Day Itinerary aboard Amatista
  • Visit Pacaya Samiria National Reser
  • Admire the incredible wildlife
  • Learn more about the Amazon culture
Starts / Ends
Iquitos / Nauta
Activities
Rainforest Exploration
Activity Level
Variable
This 4-day Amazon cruise of Iquitos & Nauta aboard Amatista gives you an insider's view of life in Peru's rainforest, including piranha fishing, wildlife spotting, visit local villages, and opportunities to learn about wildlife preservation!
Cruise Details
0
A colony of king penguins on South Georgia
from $16,943
Upgrade
EXPLORE

Springtime Expedition to Antarctica

Buenos Aires - Punta Arenas - 23 Day Itinerary aboard MS Fram
  • Discover Antarctic wildlife
  • Visit Stanley’s Dockyard Museum
  • Explore Shackleton’s grave
  • Discover Buenos Aires streets
Starts / Ends
Buenos Aires / Punta Arenas
Activity Level
Variable
Join a 23-day Antarctic cruise on MS Fram, starting in Buenos Aires and sailing to the Falkland Islands, South Georgia, and Antarctica. Experience wildlife, lectures, and Citizen Science activities, before concluding in Punta Arenas.
Cruise Details
0
Dozens of Adelie Penguins gather on an ice flow in the seawater near Brown Bluff on the Antarctica Peninsula.
from $8,480
EXPLORE

Antarctic Wonders

Roundtrip Ushuaia - 11 Day Itinerary aboard SH Vega
  • Explore Buenos Aires
  • Cruise Antarctic Peninsula
  • Capture images of Antarctic scenery
  • Explore Petermann Island
Starts / Ends
Buenos Aires / Buenos Aires
Activity Level
Variable
Embark on an 11-day Antarctica cruise aboard SH Vega. Fly south, board the boutique ship, and cross open ocean. Explore the Antarctic Peninsula with glaciers, icebergs, and wildlife. Take shore excursions to sites such as Petermann Island and the Lemaire Channel before returning to Ushuaia for your flight back to Buenos Aires.
Cruise Details
0
from $6,795
EXPLORE

Antarctica Express Air Cruise

King George Island - Ushuaia - 7 Day Itinerary aboard Magellan Discoverer
  • Visit the South Shetland Islands
  • Drake Passage navigation
  • Explore Puerto Williams
  • Chance to visit Cape Horn
Starts / Ends
Punta Arenas / Ushuaia
Activity Level
Variable
The Antarctica Express Air cruise is a compact 7-day expedition aboard Magellan Discoverer. Begin in Punta Arenas and fly to King George Island to explore penguin colonies, ice-filled bays, and Antarctic wildlife. Sail through the Drake Passage, spot seabirds and whales, and, weather permitting, land at Cape Horn. Conclude in Ushuaia.
Cruise Details
0
A whale comes up to say hello
from $17,195
EXPLORE

Antarctic Wildlife Adventure

Ushuaia to Buenos Aires - 23 Day Itinerary aboard Sea Spirit
  • Join this ultimate wildlife cruise
  • Discover incomparable landscapes
  • Visit Shackleton's resting place
  • Explore Stanley, Falkland Islands
Starts / Ends
Port of Ushuaia / Buenos Aires
Activity Level
Variable
Embark on a 23-day expedition cruise aboard the Sea Spirit from Ushuaia to Buenos Aires, exploring vibrant cities and diverse wildlife, including penguins and whales. Discover the breathtaking landscapes of the Antarctic Peninsula, South Georgia Island, and the bird-filled Falkland Islands before concluding your journey across the South Atlantic.
Cruise Details
0
A cheerful herd of penguins gathers along the icy shores of South Georgia.
from $25,195
Save 30%
EXPLORE

Falkland Islands, South Georgia & Antarctica

Roundtrip Ushuaia - 20 Day Itinerary aboard Ocean Victory
  • Cruise along Southern Ocean
  • Discover Falkland Islands wildlife
  • Visit Stanley and museums
  • Cruise Antarctic Peninsula bays
Starts / Ends
Port of Ushuaia / Port of Ushuaia
Activity Level
Variable
During this 20-day Falkland Islands, South Georgia, and Antarctica cruise aboard Ocean Victory, sail across the Southern Ocean to explore the wildlife-rich shores. Discover thriving penguin colonies, watch albatrosses in flight, see seals resting on icy beaches, navigate through iceberg-filled waters, and visit active research stations.
Cruise Details
0
Blue ice of Antarctica
from $13,495
Save 15%
EXPLORE

Antarctica: Fly the Drake Passage

Punta Arenas Roundtrip - 9 Day Itinerary aboard Ocean Nova
  • Observe South Shetland Islands
  • Visit Chilean Patagonia ranch
  • Explore King George Island
  • View Antarctic wildlife encounter
Starts / Ends
Punta Arenas / Punta Arenas
Activities
Kayaking, Wildlife Viewing, Whale Watching, Photography Seminars, Citizen Science
Activity Level
Variable
9-day expedition from Punta Arenas aboard Ocean Nova. Journey includes flight to King George Island, Antarctic Peninsula exploration via Zodiac and shore landings, visits to the South Shetland Islands, and a return via Punta Arenas with a Patagonia excursion before departure.
Cruise Details
0
Brilliant blue icebergs in Antarctic waters
from $14,490
HALF DEP
EXPLORE

Voyage to Antarctica

12 Day Itinerary aboard National Geographic Resolution
  • See legendary landscapes & habitats
  • Encounter iconic wildlife
  • Kayak, Zodiac cruise, and hike
  • Experience the Antarctic undersea
Starts / Ends
Santiago / Port of Ushuaia
Activity Level
Variable
Embark on a 12-day classic luxury Antarctica cruise aboard the National Geographic Resolution and witness the stunning beauty of huge tabular icebergs surrounded by turquoise blue meltwater pools, towering mountains rising up to 9,000 feet from the sea, countless penguins, and diverse marine mammals
Cruise Details
0
Golden light on the iconic towers of Torres del Paine National Park
from $15,724
EXPLORE

Chilean Fjords & Antarctica

Santiago - Buenos Aires - 19 Day Itinerary aboard Seabourn Pursuit
  • Explore Santiago's landmarks
  • Cruise Reloncavi Sound
  • Visit Petrohue Falls
  • Visit Bruggen Glacier's expanse
Starts / Ends
Santiago / Buenos Aires
Activity Level
Variable
Embark on a 19-day cruise from Santiago to Ushuaia aboard the Seabourn Pursuit, exploring Chile's stunning coastline, Patagonia's fjords, and the pristine wilderness of Antarctica. Highlights include volcanic landscapes, penguin colonies, and majestic glaciers.
Cruise Details
0
Riding a traditional canoe down the river
from $3,060
EXPLORE

Amazon Wildlife & Culture Journey

Iquitos Roundtrip - 7 Day Itinerary aboard La Perla
  • See pink and grey dolphins play
  • Meet and visit with locals
  • Admire the Amazon wildlife
  • Visit the birth place of the Amazon
Starts / Ends
Iquitos / Iquitos
Activity Level
Variable
This week-long river cruise onboard La Perla is ideal for flora and fauna enthusiasts who want to experience the Amazon rainforest. This region of the world is a birding enthusiast's paradise. Also, witness pink river dolphins in a way you've never seen them before.
Cruise Details
0
397-408 of 563 Results

Real experience. Honest advice.

Talk with an expert trip planner 1.800.344.6118

Plan My Trip
Shannon Fischer-Kendro Adventure Life employee profile
Shannon K.
Peruvian weavers
South America

Chat South America with a specialist

Our team is waiting and ready to talk with you about your next adventure. So go ahead and book an appointment with one of our specialized trip planners.

Let's Chat
1.800.344.6118

Where is your next adventure?

Contact Chat Call

Why Travel With Us?

Rewards That Go Further

Secure your 5% Past Traveler Rewards across a wide range of ships and destinations - not a single brand and not just cruises.

Advocacy That Matters

You're backed by a team that knows the industry and has strong relationships—helping ensure you're prioritized and well taken care of every step of the way.

Unbiased Cruise Expertise

We're not tied to any one cruise line, so you receive honest guidance on the best ship and itinerary for you—not a sales pitch.

As Featured In

How it Works

Connect

No cost, no commitment. Talk with our experts about your dream trip.

Plan

Share your travel style—we match you with the right itinerary or create one just for you.

Book

Lock in knowing every detail is handled and you’re fully supported.

Travel

Enjoy a seamless journey—and unlock 5% off your next adventure.