Have questions? We're here.
Vietnam Statue

Top My Tho Tours & Cruises in 2025

Travel made your way
Talk with an expert
Build your ideal Mekong River trip. Call 1.406.541.2677
Start Planning My Trip
Filter (34 Results)
  • Start Date
    OR, More specific start
  • Length
    to
  • Price
    to
  • Activity Levels
  • Experiences
  • Activities
  • Ships
  • Destinations
    • My Tho
The Vinh Trang Temple in My Tho, Vietnam
from $2,726
EXPLORE

From Siem Reap to the Mekong Delta

Siem Reap to Ho Chi Minh City - 9 Day Itinerary aboard RV Indochine
  • Visit Koh Chen village
  • Explore Chau Doc’s pagodas
  • Visit Cai Be workshops
  • Discover Ho Chi Minh landmarks
Starts / Ends
Siem Reap / Ho Chi Minh City
Activity Level
Variable
Set sail on a 9-day Mekong River cruise through Cambodia and Vietnam aboard RV Indochine. Explore Siem Reap, Phnom Penh, Chau Doc, Sa Dec, Cai Be, My Tho, and Ho Chi Minh City. Visit temples, markets, pagodas, and local villages while experiencing authentic cultural traditions. Enjoy guided tours, regional flavors, and cultural performances.
Cruise Details
0
Statues and intricate relief carvings inside Angkor Wat
from $4,235
EXPLORE

From the Angkor Temples to the Mekong Delta

Siem Reap to Ho Chi Minh City - 11 Day Itinerary aboard RV Indochine II
  • Visit Angkor Wat temples
  • Explore Phnom Penh landmarks
  • Visit Cu Chi tunnels in Saigon
  • Discover Koh Chen crafts
Starts / Ends
Siem Reap / Ho Chi Minh City
Activities
Local Market Visits, Land & Sea Exploration
Activity Level
Variable
Embark on an 11-day Mekong River cruise through Vietnam and Cambodia aboard RV Indochine II. Start in Siem Reap with Angkor temples, then sail across Tonle Sap Lake and explore Phnom Penh, Chau Doc, Sa Dec, Cai Be, and Ho Chi Minh City. Visit floating villages, historic landmarks, and cultural sites.
Cruise Details
0
Aerial view of Angkor Wat
from $3,215
EXPLORE

From the Mekong Delta to the Angkor Temples

Ho Chin Min City to Angkor - 11 Day Itinerary aboard RV Indochine
  • Visit Ho Chi Minh landmarks
  • Cu Chi tunnels tour
  • Explore Angkor Wat temples
  • Tour Sa Dec historic house
Starts / Ends
Ho Chi Minh City / Siem Reap
Activity Level
Variable
Experience an 11-day Mekong River cruise from Vietnam to Cambodia aboard RV Indochine. Explore Ho Chi Minh City landmarks, My Tho canals, Phnom Penh palaces, and Siem Reap’s Angkor temples. Visit bustling markets, floating villages, craft villages, and historic sites. Discover culture, tradition, and history on a unique river adventure through Southeast Asia.
Cruise Details
0
Boat floating along the Mekong River
from $3,015
EXPLORE

Mekong River - Downstream - High water

Siem Reap to Saigon - 8 Day Itinerary aboard The Jahan
  • Explore Kampong Laeang
  • Discover Phnom Penh
  • Tour Gieng Island
  • Explore Binh Thanh Island
Starts / Ends
Siem Reap / My Tho
Activity Level
Variable
Journey from Siem Reap to Saigon on an 8-day Mekong River cruise aboard The Jahan. Discover Cambodia’s rural villages, temples, and Phnom Penh’s historic sites before crossing into Vietnam’s Mekong Delta. Visit Gieng, My An Hung, and Binh Thanh Islands, meeting local artisans and experiencing daily life along the river.
Cruise Details
0
The beautiful Vinh Trang temple near My Tho
from $3,015
EXPLORE

Mekong River - Upstream - High water

Saigon - Siem Reap - 8 Day Itinerary aboard The Jahan
  • Tour Phnom Penh City
  • Visit Angkor Ban Monastery
  • See Kampong Luong Silversmith
  • Explore Tonle Lake
Starts / Ends
My Tho / Siem Reap
Activity Level
Variable
Experience an 8-day Mekong River cruise from Saigon to Siem Reap aboard The Jahan. Discover floating villages, fruit farms, temples, and vibrant riverside life across Vietnam and Cambodia. Explore Phnom Penh’s historic sites, meet local artisans, and travel through the Tonle Lake region, a UNESCO Biosphere Reserve.
Cruise Details
0
Bike in front of Angkor Wat
from $6,370
EXPLORE

From the Mekong Delta to the Temples of Angkor & Hanoi and Halong Bay

Hanoi to Angkor Temples - 14 Day Itinerary aboard RV Indochine II
  • Explore Hanoi’s historic sites
  • Learn Cambodian history
  • Ride sampans through canals
  • Cruise scenic Halong Bay
Starts / Ends
Hanoi / Siem Reap
Activity Level
Variable
Travel from Hanoi to Siem Reap on a 14-day cruise-tour aboard RV Indochine II. Explore Vietnam’s capital, cruise Halong Bay, and visit Ho Chi Minh City. Journey along the Mekong River to discover floating villages, bustling markets, and temples.
Cruise Details
0
Angkor Wat
from $5,804
EXPLORE

From the Temples of Angkor to the Mekong Delta & Hanoi and Halong Bay

Siem Reap to Halong Bay - 14 Day Itinerary aboard RV Indochine II
  • Angkor Wat exploration
  • Explore Tonle Sap villages
  • Explore Sa Dec markets
  • Discover Hanoi's historic sites
Starts / Ends
Siem Reap / Hanoi
Activities
Urban Exploration
Activity Level
Variable
Explore Vietnam and Cambodia on a 14-day cruise combining river cruising aboard RV Indochine II and cultural tours. Visit Angkor temples, Tonle Sap Lake, Phnom Penh, Chau Doc, Sa Dec, Ho Chi Minh City, Hanoi, and Halong Bay. Discover vibrant markets, ancient pagodas, floating villages, and historic landmarks.
Cruise Details
0
The Vinh Trang Temple in My Tho
from $4,784
EXPLORE

From the Mekong Delta to the Temples of Angkor & Hanoi and Halong Bay

Hanoi to Angkor Temples - 14 Day Itinerary aboard RV Indochine
  • Experience Hanoi city tour
  • Cruise along Halong Bay's islands
  • Explore Ho Chi Minh landmarks
  • Explore My Tho bee farm
Starts / Ends
Hanoi / Siem Reap
Activity Level
Variable
Discover Vietnam and Cambodia on a 14-day cruise from Hanoi to Siem Reap aboard RV Indochine. Cruise Halong Bay, explore Ho Chi Minh City, visit Phnom Penh, and marvel at Angkor temples. Enjoy guided tours, local markets, floating villages, and authentic cuisine with unique cultural experiences along the Mekong River.
Cruise Details
0
Bike ride by Angkor Wat Temple
from $11,350
OBC
EXPLORE

Wonders of Cambodia, Vietnam and the Mekong

Siem Reap - Ho Chi Minh - 13 Day Itinerary aboard Emerald Harmony
  • Explore ancient Angkor Thom
  • Discover temples at Ta Prohm
  • Visit Kampong Tralach
  • Tour Vietnam’s rural life
Starts / Ends
Siem Reap / Ho Chi Minh City
Activities
Wildlife Viewing
Activity Level
Variable
Experience a 13-day cruise on the Emerald Harmony, starting in Siem Reap with guided tours of Angkor Wat and other iconic sites. Journey through the Mekong River, exploring Phnom Penh and the Mekong Delta, before concluding with two nights in Ho Chi Minh City, blending culture and heritage in Cambodia and Vietnam.
Cruise Details
0
Phnom Penh Golden Temple
from $4,299
EXPLORE

Mekong River - Upstream - Low water

Saigon - Siem Reap - 8 Day Itinerary aboard The Jahan
  • Visit Phnom Penh landmarks
  • Explore Kampong Laeang pottery
  • Meet Binh Thanh weavers
  • Explore Angkor Ban village
Starts / Ends
My Tho / Siem Reap
Activity Level
Variable
Journey 8 days from Saigon to Siem Reap aboard The Jahan, exploring the Mekong River’s changing landscapes and riverside life. Visit workshops in Cai Be, fruit gardens on Tan Phong Island, and communities in Cambodia that craft silver, weave silk, and make mats. Discover Phnom Penh, Angkor Ban, and the temples near Kampong Cham.
Cruise Details
0
Sunset over the Mekong River
from $4,299
EXPLORE

Mekong River - Downstream - Low water

Siem Reap to Saigon - 8 Day Itinerary aboard The Jahan
  • Discover Gieng Island Workshops
  • Explore Angkor Ban Village
  • Tour Phnom Penh Landmarks
  • Visit Binh Thanh Island
Starts / Ends
Siem Reap / My Tho
Activities
Spa Relaxation
Activity Level
Variable
Sail for 8 days aboard the Jahan from Siem Reap to Saigon, uncovering the heart of Cambodia and Vietnam along the Mekong River. Visit floating villages, temples, and traditional workshops in Phnom Penh, Kampong Tralach, and the Mekong Delta. Enjoy cultural encounters, local cuisine, and daily guided excursions.
Cruise Details
0
Harvesting rice in Vietnam
from $2,782
EXPLORE

Mekong River - Upstream - High water

Saigon to Siem Reap - 8 Day Itinerary aboard Jayavarman
  • Witness Cai Be Candy Making
  • Discover skilled craftsmanship
  • Experience scenic views at Delta
  • Tour Phnom Penh
  • Discover cultures of Mekong Delta
Starts / Ends
Ho Chi Minh City / Siem Reap
Activity Level
Variable
Embark on an 8-day Mekong River cruise aboard the Jayavarman, from Saigon to Siem Reap. Experience the beauty and culture of the lower Mekong River, explore charming riverside towns, and uncover the rich history and traditions that define this remarkable region.
Cruise Details
0
The beautiful Vinh Trang temple near My Tho
from $3,788
EXPLORE

Mekong River - Upstream - Low water

Saigon - Siem Reap - 8 Day Itinerary aboard Jayavarman
  • Aboard a luxury riverboat in Mekong
  • Visit Cai Be workshops
  • Explore Tan Phong Island
  • Cruise the Tonle River
  • Meet monks in Angkor Ban
Starts / Ends
Ho Chi Minh City / Siem Reap
Activity Level
Variable
Sail the Mekong River aboard the Jayavarman on an 8-day cruise from Saigon to Siem Reap. Discover local life along the river, from Vietnam’s craft villages and island communities to Cambodia’s temples, silk weaving villages, and cultural traditions.
Cruise Details
0
Sunset over the Mekong River
from $2,782
EXPLORE

Mekong River - Downstream - High water

Siem Reap to Saigon - 8 Day Itinerary aboard Jayavarman
  • Explore Tonle Lake by boat
  • Visit Kampong Laeang villages
  • Discover Phnom Penh’s history
  • Cross into Vietnam
  • Explore Gieng Island
Starts / Ends
Siem Reap / Ho Chi Minh City
Activities
Village Visits, Archaeological Site Visits, Cooking Classes
Activity Level
Variable
Sail aboard the Jayavarman on an 8-day Mekong River cruise from Siem Reap to Saigon. Explore Cambodia’s Tonle Lake, Phnom Penh’s historic sites, and Vietnam’s colorful Mekong Delta villages while discovering local crafts, culture, and daily river life.
Cruise Details
0
Sunset over the Mekong River
from $2,782
EXPLORE

Mekong River - Downstream - High water

Siem Reap to Saigon - 8 Day Itinerary aboard Jayavarman
  • Aboard a luxury riverboat in Mekong
  • See the floating market in Cai Be
  • Observed locals along the river
  • Visit Tan Chau floating fish farm
  • Visit Phnom Penh cultural sites
Starts / Ends
Siem Reap / Ho Chi Minh City
Activity Level
Variable
Explore the Mekong on this 8-day high-water Mekong River cruise from Siem Reap to Saigon. Get an inside look at the southern cultures of Vietnam and Cambodia as you travel across the mighty Mekong Delta. Stop in charming port towns and immerse yourself in the city's culture and history.
Cruise Details
0
Ben Tre biking on a country lane
from $892
EXPLORE

Biking the Mekong Delta

3 Day Itinerary
  • Enjoy home-cooked meals
  • Cycle through small Delta villages
  • Explore Cai Rang Floating Market
Starts / Ends
Ho Chi Minh City / Ho Chi Minh City
Activities
Biking
Activity Level
Moderate
Cycle through small villages, past rice fields, and to vibrant markets as you explore the Mekong Delta on this 3-day Vietnam extension. Ride through Cai Be, Vinh Long, and Can Tho, exploring rural landscapes, the famous Cai Rang Floating Market, and local culture. Extend your Vietnam tour with this intimate exploration of the Mekong Delta region.
Tour Details
0
19-34 of 34 Results

Top Mekong River Travel Destinations

Mekong River Trips by Departure Date

Top Experiences in Mekong River

Mekong River Trips by Duration

Mekong River Trips by Activity

More Reasons

Why Travel With Adventure Life

All News

Recognized By