Top Mekong River Trips & Tours in September 2025

from $1,243

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Mekong River - Upstream

Saigon to Phnom Penh - 4 Day Itinerary aboard The Jahan

Starts / Ends

Ho Chi Minh City / Phnom Penh

Activity Level

Variable

On this 4-day journey from Saigon to Phnom Penh, cruise the lower Mekong River in majestic style aboard the Jahan. Discover the culture and history of the various towns along the mighty Mekong while exploring the river.

• Observed locals along the river
• See the floating market in Cai Be
• Visit Phnom Penh cultural sites
• Visit Tan Chau floating fish farm

Cruise Details

0

from $3,039

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Charms of the Mekong - Cruise Only

Ho Chi Minh - Siem Reap - 8 Day Itinerary aboard MS Amadara

Starts / Ends

Ho Chi Minh City / Siem Reap

Activity Level

Variable

Embark on an 8-day river cruise aboard the MS Amadara, starting in Ho Chi Minh City, a vibrant blend of history and modernity. Cruise the Mekong River, exploring villages, pagodas, and markets and experiencing local traditions, including a monk’s blessing and artisan crafts.

• Explore Cai Be’s vibrant workshops
• Discover Sa Dec history
• Visit Phnom Penh landmarks
• Experience Oknhatey, silk weaving

Cruise Details

0

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Experience the Mekong by Cruise

1 Day Itinerary

Starts / Ends

Mekong River / Mekong River

Activity Level

Relaxed

This one-day Vietnam tour extension includes a cruise along the Mekong River and visits to other scenic locations. Visit Ben Tre, My Long, a coconut workshop, a bee garden, a candy mill, and a farmer's house, and ride a rickshaw past coconut trees and vegetable farms.

• Visit a candy mill
• Visit a coconut workshop
• Enjoy biking or ride on a rickshaw

Tour Details

0

from $1,231

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Mekong River - Downstream

Phnom Penh to Saigon - 4 Day Itinerary aboard Jayavarman

Starts / Ends

Phnom Penh / Ho Chi Minh City

Activity Level

Variable

Cruise downstream on the Mekong River in majestic style aboard the Jayavarman on this 4-day journey from Phnom Penh to Saigon. Learn about the culture and heritage with visits to rural villages, historic pagodas, and colorful markets

• Observed locals along the river
• Aboard a luxury riverboat in Mekong
• Visit Phnom Penh cultural sites
• Visit Tan Chau floating fish farm

Cruise Details

0

from $10,290

NO SS

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Mekong Expedition - Ho Chi Minh to Siem Reap (Extension)

Low water - 8 Day Itinerary aboard Aqua Mekong

Activity Level

Variable

From Ho Chi Minh, Vietnam to Phnom Penh, Cambodia, luxurious Aqua Mekong takes you on this 8-day Mekong River cruise, visiting Buddhist temples, local villages & markets, and touring Chau Doc, Kampong Chhnang, Kampong Tralach, Koh Oknha Tey, and Sa Dec.

• Discover My An Hung
• Enjoy a traditional performance
• Learn to cook Mekong dishes
• Visit Cambodia's National Museum
• Past by Buddhist temples

Cruise Details

0

from $1,243

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Mekong River - Downstream

Phnom Penh to Saigon - 4 Day Itinerary aboard The Jahan

Starts / Ends

Phnom Penh / My Tho

Activities

Biking

Activity Level

Variable

On this 4-day journey from Phnom Penh to Saigon, cruise downstream on the lower Mekong River in majestic style aboard the Jahan. See the stunning scenery and discover the culture and history of the various towns along the mighty Mekong.

• Experience Binh Thanh Island
• Explore My An Hung Village
• Discover Tan Chau
• Experience Cao Dai

Cruise Details

0

from $10,290

NO SS

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Mekong Expedition - Phnom Penh to Ho Chi Minh

8 Day Itinerary aboard Aqua Mekong

Starts / Ends

Phnom Penh / Ho Chi Minh City

Activity Level

Variable

Admire the diverse cultures and stunning natural beauty of Cambodia & Vietnam on this 8-day small ship cruise aboard Aqua Mekong. Hikes and bike rides complement cultural tours and market visits as you explore the cities & sites of Cai Be, Chau Doc, Ho Chi Minh City, Kampong Chhnang, Kampong Tralach, Koh Chen, Phnom Penh.

• Walk across Kampong Prasat
• Learn more about the local products
• Visit the Tuol Sleng Museum
• Discover Tan Chau

Cruise Details

0

from $1,231

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Mekong River - Upstream

Saigon to Phnom Penh - 4 Day Itinerary aboard Jayavarman

Starts / Ends

Ho Chi Minh City / Phnom Penh

Activity Level

Variable

On this 4-day journey from Saigon to Phnom Penh, cruise the lower Mekong River in majestic style aboard the Jayavarman. Discover the culture and history of the various towns along the mighty Mekong while exploring the river.

• Observed locals along the river
• See the floating market in Cai Be
• Visit Phnom Penh cultural sites
• Visit Tan Chau floating fish farm

Cruise Details

0

from $3,529

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From the Angkor Temples to the Mekong Delta

Siem Reap - Ho Chi Minh - 11 Day Itinerary aboard RV Indochine

Starts / Ends

Siem Reap / Ho Chi Minh City

Activity Level

Variable

Experience an 11-day cruise on the RV Indochine from Siem Reap to Ho Chi Minh City, navigating over 2,700 miles of the Mekong River. Explore cultural landmarks like Angkor and Phnom Penh, all while enjoying colonial-inspired comfort aboard your vessel.

• Visit the Banteay Srei temple
• Explore the terrace of Elephants
• Discover Kampong Chhnang
• Tour Phnom Penh's National Museum

Cruise Details

0

from $10,290

NO SS

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Mekong Expedition - Ho Chi Minh to Siem Reap

High water - 8 Day Itinerary aboard Aqua Mekong

Starts / Ends

Ho Chi Minh City / Siem Reap

Activity Level

Variable

Board the Aqua Mekong for an unforgettable 8-day cruise up the Mekong River from Saigon, Vietnam to Siem Reap, Cambodia, with stops in Phnom Penh and Tonle Sap Lake, among other highlights of the Indochina peninsula. Biking, hiking, cultural immersion, market visits, and cooking classes highlight the cruise.

• Experience vibrant markets
• Enjoy touring Cambodia's capital
• Visit Long Son Pagoda
• Explore Prek Toal Core Bird Reserve

Cruise Details

0

from $2,939

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Riches of the Mekong - Cruise Only

8 Day Itinerary aboard MS Amadara

Starts / Ends

Siem Reap / Ho Chi Minh City

Activities

Wildlife Viewing

Activity Level

Variable

Embark on an 8-day river cruise from Siem Reap to Ho Chi Minh aboard the MS Amadara, exploring rural villages, bustling markets, and historic sites. Experience Cambodia and Vietnam’s rich culture through artisan crafts, temple visits, and unique rides by oxcart, tuk-tuk, and trishaw.

• Explore Angkor Ban village
• Visit Oknhatey, Silk Island
• Tour Phnom Penh highlights
• Discover Oudong, royal capital

Cruise Details

0

from $6,200

NO SS

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Mekong Explorer - Ho Chi Minh to Siem Reap (Extension)

5 Day Itinerary aboard Aqua Mekong

Starts / Ends

Ho Chi Minh City / Phnom Penh

Activities

Spa Relaxation

Activity Level

Variable

Board the Aqua Mekong in My Tho for a 5-day Mekong River cruise of Cambodia & Vietnam, including stops in Ho Chi Minh City, Phnom Penh, and Long Son Pagoda atop Sam Mountain. Travel back in time as you cruise upriver through the thriving Mekong Delta past floating villages, colonial vestiges, and gilded pagodas.

• Enjoy a visit to a local's home
• Walk through verdant plantations
• Meet & interact with Buddhist Monks

Cruise Details

0

from $2,741

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Mekong River - Downstream - High water

Siem Reap to Saigon - 8 Day Itinerary aboard The Jahan

Starts / Ends

Siem Reap / Ho Chi Minh City

Activity Level

Variable

Join this 8-day Mekong River cruise during the high water season from Siem Reap to Saigon. Get an inside look at the southern cultures of Vietnam and Cambodia as you travel across the mighty Mekong delta. Stop in charming port towns and immerse yourself in the city's culture and history.

• Aboard a luxury riverboat in Mekong
• See the floating market in Cai Be
• Observed locals along the river
• Visit Tan Chau floating fish farm
• Visit Phnom Penh cultural sites

Cruise Details

0

from $2,529

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Mekong River - Upstream - High water

Saigon to Siem Reap - 8 Day Itinerary aboard Jayavarman

Starts / Ends

Ho Chi Minh City / Siem Reap

Activities

Local Market Visits, Village Visits, Archaeological Site Visits

Activity Level

Variable

Embark on this 8-day high river expedition on the Jayavarman and experience the Mekong River as it flows from Saigon to Siem Reap. Explore the lower Mekong and discover the diverse cultures and historical significance of the towns along its course.

• Explore rural villages
• Discover skilled craftsmanship
• Experience scenic views at Delta
• Explore floating markets
• Discover cultures of Mekong Delta

Cruise Details

0

from $2,529

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Mekong River - Downstream - High water

Siem Reap to Saigon - 8 Day Itinerary aboard Jayavarman

Starts / Ends

Siem Reap / Ho Chi Minh City

Activities

Cooking Classes

Activity Level

Variable

Explore the Mekong on this 8-day high-water Mekong River cruise from Siem Reap to Saigon. Get an inside look at the southern cultures of Vietnam and Cambodia as you travel across the mighty Mekong Delta. Stop in charming port towns and immerse yourself in the city's culture and history.

• Aboard a luxury riverboat in Mekong
• See the floating market in Cai Be
• Observed locals along the river
• Visit Tan Chau floating fish farm
• Visit Phnom Penh cultural sites

Cruise Details

0

from $5,098

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From the Temples of Angkor to the Mekong Delta & Hanoi and Halong Bay

14 Day Itinerary aboard RV Indochine

Starts / Ends

Siem Reap / Hanoi

Activities

Urban Exploration

Activity Level

Variable

This 14-day Mekong River cruise through Cambodia and Vietnam aboard the RV Indochine travels from Siem Reap in Cambodia to Hanoi, Vietnam observing imposing monuments, examples of finest architecture, and extraordinary landscapes, like those of famous Angkor Wat. Also visit Chau Doc, Ho Chi Minh City, Kampong Tralach, Koh Chen, My Tho, Sa Dec, & Tonle Sap Lake.

• Discover 3 historical cities
• Cross through the Cho Gao canal
• Visit 4 major temples in Angkor
• Meet locals and learn their culture

Cruise Details

0

from $4,650

NO SS

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Mekong Discovery - Phnom Penh to Siem Reap

High water - 4 Day Itinerary aboard Aqua Mekong

Activity Level

Variable

Experience the colorful culture of Vietnam and Cambodia as you embark on this 4-day Mekong River Discovery Cruise and experience a richly-rewarding adventure by heading upriver in Cambodia and exploring the Tonle Sap Lake.

• Experience an indigenous tradition
• Discover Koh Chen´s pottery
• Explore the Moat Khla village

Cruise Details

0

from $6,018

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Charms of the Mekong

16 Day Itinerary aboard MS Amadara

Starts / Ends

Ho Chi Minh City / Hanoi

Activities

Land & Sea Exploration

Activity Level

Variable

Embark on a 16-day cruise aboard the MS Amadara. Explore the Mekong, visit rural villages and ancient temples, and discover Angkor’s UNESCO sites in Siem Reap before concluding with an overnight stay at Ha Long Bay.

• Explore Ho Chi Minh vibrant city
• Visit Phnom Penh historic palaces
• Discover Cai Be markets
• Tour Siem Reap ancient temples

Cruise Details

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