Enjoy Patmos Cruises (sometimes referred to as the Holy Island due to its significance in the Christian religion and pure beauty) just off the mainland of Greece located on the Aegean Sea. This small island has a population of around 3,000 inhabitants and the official language on the island is Greek. Take a tour to the cultural hub of the Monastery of St. John, the Holy Cave of Apocalypse, or the Chora Patmos. Saint John wrote the Book of Revelation on Patmos which is why the Monastery is named as such. Combine your Greek cruise with a cruise to the neighboring Croatia and Italy to explore magnificent Venice or Rome. Or, venture the other direction to Turkey to visit Istanbul on a Mediterranean Cruise! What your itinerary holds is completely up to you! Contact our Greek small ship cruise specialists to begin planning your personalized trip throughout the Mediterranean Sea.

All Greece Tours

10 Best Patmos Small Ship Cruises for 2026-2027

All Greece Tours

6 Top-Rated Patmos Luxury Small Ship Cruises for 2026-2027

Cruising the Greek Islands of the Southern Aegean: with Smithsonian Journeys

8 Days from $8,070

Embark on an 8-day Aegean cruise from Athens, exploring ancient ruins, charming islands, and vibrant modern life. Visit Patmos, Rhodes, Crete's Heraklion and Knossos, Amorgos' traditional villages, Delos' sacred ruins, Mykonos' chic resorts, and Nafplion's Mycenae and Epidaurus before returning to Athens.

Cruising the Aegean: Turkey and the Greek Isles – with Smithsonian Journeys

8 Days from $7,450

Cruise through Greece and Turkey aboard Le Boreal on an 8-day cruise. Visit iconic destinations like Athens, Nafplion, Paros, Delos, Mykonos, Kusadasi, Patmos, Canakkale, and Istanbul. Explore UNESCO landmarks, ancient ruins, picturesque villages, and turquoise coves. A perfect blend of history, culture, and breathtaking scenery awaits.

At the heart of the Greek Islands

8 Days from $6,620

Sail through the heart of Greece on an unforgettable 8-day cruise, starting and ending in the historic city of Athens. Discover the magic of the Cyclades and the Dodecanese as you explore iconic destinations like Santorini, Delos, and Milos, alongside hidden gems such as Symi and Amorgos.

Antique wonders of the Aegean

9 Days from $6,870

Discover the Aegean’s treasures on this 9-day cruise aboard the Le Boreal from Istanbul. Explore charming islands, sacred sites, and stunning landscapes, ending with Hydra’s serenity and Athens’ iconic Acropolis.

Cruising the Greek Isles

10 Days from $14,895

Sail through Greece on a 12-day luxury cruise aboard Le Dumont d’Urville, from ancient Athens to sun-soaked islands like Santorini, Mykonos, and Patmos. Explore iconic ruins, whitewashed villages, and hidden gems with guided tours, hands-on culinary experiences, and exclusive cultural encounters that reveal the true heart of the Greek Isles.

Cruising the Aegean: Turkey and the Greek Isles – with Smithsonian Journeys

8 Days from $11,970

Cruise through Greece and Turkey aboard Le Dumont-d'Urville on an 8-day cruise. Visit iconic destinations like Athens, Nafplion, Paros, Delos, Mykonos, Kusadasi, Patmos, Canakkale, and Istanbul. Explore UNESCO landmarks, ancient ruins, picturesque villages, and turquoise coves. A perfect blend of history, culture, and breathtaking scenery awaits.

Greece Travel Articles

Patmos Travel Guide

Top 12 Things to Do in the Dodecanese Islands - Must-See Attractions & Experiences

Discover the top 12 things to do and see on the Dodecanese Islands and make the most of your Greek island adventure!

Witness the Changing of the Guard in Athens

Greece Overview

Often called the cradle of western civilization, Greece maintains a rich culture that has evolved over thousands of years and has influenced people throughout the world. With so much history and deep-rooted traditions, travel to this destination evokes a truly unique sense of cultural romance.

Introduction to the Mediterranean

Summer is the high travel season in the Mediterranean. The best time to take a Mediterranean cruise, however, is in the spring (May-June) or fall (September-October).

How to Choose a Mediterranean Cruise

Cruise the Mediterranean with Adventure Life and enjoy turquoise waters, ancient cities, and charming coastal towns. Explore Italy, Greece, the Dalmatian Coast, and more on small ships or yachts. Our Trip Planners customize your journey to fit your lifestyle, interests, and budget perfectly.

Relax on the beaches of the French Riviera

Top Mediterranean Cruise Ports

The temperate climate of the Mediterranean makes it a delightful destination to visit on a luxury cruise. Coupled with explorations of historic cities and archaeological sites and plenty of active day excursions, from swimming and snorkeling in turquoise waters to hiking and biking around the ancient ruins and rolling valleys, you don’t have to travel beyond the ports to find a world of adventure.

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