Have questions? We're here.
Looking over Florence at the Basilica di Santa Maria del Fiore.

Palermo Small Ship Cruises

Travel made your way ™
Talk with an expert
Build your ideal Mediterranean trip. Call 1.406.541.2677
Start Planning My Trip
Talk with an expert
Experience the enchanting Mediterranean allure of the Italian city of Palermo with Adventure Life's cruises. Join us on a cruise journey through the vibrant Sicilian heritage, ancient ruins, Byzantine-Arab mosaics, and medieval towns. Delve into the local cuisine, from Sicily to Sardinia, Corsica, and Elba, and admire the stunning landscapes of the region. Embark on an 8-day Mediterranean Island Voyage with Smithsonian Journeys aboard Le Bougainville, or opt for a 9-day Circumnavigation of Sicily aboard Le Champlain. Discover Taormina, marvel at a volcano, explore different cultures, and sail from the French Riviera to the Turkish Riviera on various captivating itineraries. Engage in archaeological site visits, village explorations, and relaxed cultural programs suitable for all travelers. Don't miss this opportunity to immerse yourself in the rich history, culture, and landscapes of Palermo. Contact one of Adventure Life's tour specialists for help planning your next seamless trip.
Filter (10 Results)
  • Start Date
    OR, More specific start
  • Length
    to
  • Price
    to
  • Activity Levels
  • Experiences
  • Activities
  • Ships
  • Destinations
    • Palermo
Relax in beautiful Sicily
from $3,390
EXPLORE

Sicilian Sunsets & Amalfi Delights

Malta - Naples - 8 Day Itinerary aboard Variety Voyager
  • Explore Agrigento’s Temple Valley
  • Marvel at Trapani’s medieval street
  • Discover Erice’s Venus Castle
  • Taste Palermo’s food delights
Starts / Ends
Valletta / Naples
Activity Level
Variable
Embark on an 8-day cruise aboard the Variety Voyager from Valletta to Sicily and Southern Italy, exploring historic cities and stunning coastlines. Discover Agrigento, Erice, and Pompeii while enjoying exclusive onboard experiences and authentic Sicilian cuisine.
Cruise Details
0
Beautiful Taormina, Italy, with Mt. Etna in the background
from $7,750
EXPLORE

Mediterranean Island Voyage: Sicily, Sardinia, Corsica, and Elba – with Smithsonian Journeys

Nice - Valletta - 8 Day Itinerary aboard Le Dumont-d'Urville
  • Wander Nice Cours Saleya markets
  • Discover Bonifacio limestone cliffs
  • Tour Cagliari old ramparts
  • See Valletta Barrakka Gardens
Starts / Ends
Nice / Valletta
Activity Level
Variable
Set sail on an 8-day Mediterranean cruise aboard Le Dumont-d'Urville, visiting Napoleon's residence in Portoferraio, the medieval streets of Bonifacio, and the vibrant markets of Palermo. Conclude your journey in Valletta, Malta, exploring the Grandmaster's Palace and St. John's Cathedral.
Cruise Details
0
The rocky cliffs of Calabria, Italy
from $8,510
EXPLORE

Authentic Mediterranean Shores

Valletta Roundtrip - 10 Day Itinerary aboard Le Boreal
  • Walk Valletta’s historic streets
  • Visit Palermo’s Palatine Chapel
  • Discover Lipari’s volcanic cliffs
  • Explore Trapani’s cultural sites
Starts / Ends
Valletta / Valletta
Activity Level
Variable
Embark in Valletta for a 10-day Mediterranean cruise to Sicily and southern Italy aboard Le Boreal. Explore Syracuse, Palermo, Lipari, Taormina, and Pompeii. Visit temples, amphitheaters, cathedrals, and volcanic sites. Enjoy views of Stromboli and Etna, then return to Malta aboard a luxury ship with cultural programming and refined comfort.
Cruise Details
0
Sunset over Palermo
from $9,120
EXPLORE

Mediterranean Island Voyage: Sicily, Sardinia, Corsica, and Elba – with Smithsonian Journeys

Valletta - Nice - 9 Day Itinerary aboard Le Dumont-d'Urville
  • Explore Valletta Barrakka Gardens
  • Discover Gozo temples of Ggantija
  • Tour Taormina Greco-Roman theater
  • See Cagliari old ramparts
Starts / Ends
Valletta / Nice
Activity Level
Variable
Experience a 9-day Mediterranean cruise on the Le Dumont-d'Urville, exploring historic sites in Malta, Sicily, and Sardinia. Conclude your cruise in Nice after visiting picturesque landscapes and cultural landmarks throughout the region.
Cruise Details
0
Mount Etna looms over an ancient town
from $14,595
EBD
EXPLORE

The Amalfi, Sicily and Malta: The Godfather

Rome - Valletta - 13 Day Itinerary aboard MV Douglas Mawson
  • Explore Rome to view the Colosseum
  • Explore Gaeta monastery site
  • Sail the Amalfi Coast
  • Wander Agrigento and Greek ruins
Starts / Ends
Rome / Valletta
Activities
Wine Tasting
Activity Level
Variable
Embark on a 13-day Mediterranean cruise aboard the Douglas Mawson, exploring Sicily, Malta, and the stunning Amalfi Coast. Experience ancient architecture, rich histories, and the region's famous cuisine amidst scenic coastal landscapes.
Cruise Details
0
Explore Agropoli, Italy
from $3,350
EXPLORE

Sicily Unveiled with Italian Treasures

Roundtrip Civitavecchia - 11 Day Itinerary aboard Star Clipper
  • Sail coastlines of Sicily
  • Cruise Aeolian Islands
  • Visit Trapani port
  • Explore Palermo streets
Starts / Ends
Civitavecchia / Civitavecchia
Activities
Small Ship Sailing
Activity Level
Variable
Sail Italy’s southern coast on an 11-day cruise aboard Star Clipper. Experience Sicily, the Aeolian Islands, Calabria, and the Amalfi Coast, navigating volcanic landscapes, historic ports, and small island harbors for an intimate sailing experience.
Cruise Details
0
Enjoy stunning sunset views over Zadar
from $17,795
Save $150
EXPLORE

Adriatic, Sicily & the Amalfi Coast

Civitavecchia - Venice - 12 Day Itinerary aboard Scenic Ikon
  • Explore Rome elaborate churches
  • Discover Capri Piazzetta
  • See Lipari pastel townhouses
  • Experience Palermo arancini
Starts / Ends
Civitavecchia / Venice
Activities
Urban Exploration, Archaeological Site Visits, Village Visits, Local Market Visits
Activity Level
Variable
Set sail on a 12-day cruise from Civitavecchia, exploring Rome, Sicily, and the Amalfi Coast. Experience luxury aboard the Scenic Ikon while tasting Mediterranean cuisine and discovering unique cultures in breathtaking destinations.
Cruise Details
0
from $9,540
EXPLORE

Culture and Islands of the Mediterranean

Barcelona - Valletta - 12 Day Itinerary aboard L'Austral
  • Visit Menorca
  • Explore Sardinia
  • Discover Sicily
  • Experience Catania
  • Discover Syracuse
  • Discover Malta
Starts / Ends
Barcelona / Valletta
Activity Level
Variable
Embark on a 12-day cruise from Barcelona to Malta aboard L’Austral. Enjoy culinary and cultural experiences with an included excursion per port. Highlights include Menorca, Alghero, Cagliari, Trapani, Palermo, Lipari, Catania, Syracuse, Gozo, and ending in Valletta.
Cruise Details
0
Relax in beautiful Sicily
from $9,490
EXPLORE

A Circumnavigation of Sicily with Smithsonian Journeys

Valletta Roundtrip - 9 Day Itinerary aboard Le Dumont-d'Urville
  • Visit Valleta a UNESCO-listed city
  • Visit Valley of Temples
  • Witness a fiery volcano
  • Discover Trapani's diverse heritage
Starts / Ends
Valletta / Valletta
Activity Level
Variable
Set sail on a 9-day Sicily cruise aboard Le Dumont-d'Urville. Visit UNESCO sites like Valletta and the Valley of Temples, admire Stromboli’s volcanic activity, explore vibrant cities such as Palermo and Syracuse, and discover ancient ruins, diverse cultures, and beautiful coastal views.
Cruise Details
0
Coast of Ortigia island at city of Syracuse
from $8,930
EXPLORE

A Circumnavigation of Sicily with Smithsonian Journeys

Valetta Roundtrip - 9 Day Itinerary aboard Le Laperouse
  • Visit Valleta a UNESCO-listed city
  • Visit Valley of Temples
  • Witness a fiery volcano
  • Discover Trapani's diverse heritage
Starts / Ends
Valletta / Valletta
Activity Level
Variable
Set sail on a 9-day Sicily cruise aboard Le Laperouse. Visit UNESCO sites like Valletta and the Valley of Temples, admire Stromboli’s volcanic activity, explore vibrant cities such as Palermo and Syracuse, and discover ancient ruins, diverse cultures, and beautiful coastal views.
Cruise Details
0
1-10 of 10 Results
  • 1

Let us match you to your best adventure.

Talk with an expert trip planner 1.800.344.6118

Plan My Trip
Kelly Carlin Adventure Life employee profile
Kelly C.
Looking over Florence at the Basilica di Santa Maria del Fiore.
Mediterranean

Chat Palermo with a specialist

Our team is waiting and ready to talk with you about your next adventure. So go ahead and book an appointment with one of our specialized trip planners.

Let's Chat
1.800.344.6118

Where is your next adventure?

Contact Chat Call

Why Travel With Us?

Peace of Mind

You'll work with a team of humans who get to know you, answer every question, and support you until you return home—we're always just a call or text away.

One Seamless Journey

We bring cruise and land together into a single, well-orchestrated experience—so your trip feels cohesive, not pieced together.

Unbiased Cruise Expertise

We're not tied to any one cruise line, so you receive honest guidance on the best ship and itinerary for you—not a sales pitch.

As Featured In

USA Today
Los Angeles Times
Travel Weekly
Outside
National Geographic Traveler
The New York Times
Travel + Leisure
Condé Nast Traveler
National Geographic

How it Works

Connect

No cost, no commitment. Talk with our experts about your dream trip.

Plan

Share your travel style—we match you with the right itinerary or create one just for you.

Book

Lock in knowing every detail is handled and you’re fully supported.

Travel

Enjoy a seamless journey—and unlock 5% off your next adventure.

Kelly Carlin Adventure Life employee profile
Kelly C
Plan My Trip
We love travel, talk with an expert 1.800.344.6118