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Top Mississippi River Trips & Tours in 2024

Travel made your way
New Orleans
Sean Pavone
Visit the famed Bourbon Street
St Louis
Sean Pavone
View the iconic arch when you visit St. Louis, gateway to the west
Vicksburg
Michael Warren
View a Civil War battlefields in Mississippi
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Discover Mississippi River in 2024 on one of these amazing trips hand selected by the travel experts at Adventure Life. Select any of the below 32 top-rated trips where you will explore Memphis, New Orleans, St. Louis, Vicksburg, and Natchez with an exceptional bilingual guide on a small group or customizable private tour. The most popular things to do in Mississippi River in 2024 are river cruises, cruises, cultural, archaeological site visits, and village visits. Our Mississippi River trips in 2024 range in price from $2,399 to $28,499 for trips of 8 to 16 days. Contact one of Adventure Life's expert Mississippi River trip planners for help planning a seamless experience.
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    • Mississippi River
Explore the rivers of America
$5,599
EXPLORE

St. Louis to Minneapolis

9 Day Itinerary aboard American Duchess
  • Explore the culture of St. Louis
  • See Mark Twain's hometown, Hannibal
  • Relax in laid-back La Crosse
  • Admire local artwork in Red Wing
Starts / Ends:
St. Louis / Red Wing
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Explore the land and river that inspired legendary American author Samuel Clemens, better known by his pen name, Mark Twain. Cruise northward from St. Louis, Missouri along the mighty Mississippi River, toward the city of Minneapolis. Along the way, explore port towns such as Hannibal, Missouri, …
Cruise Details
0
New Orleans paddlewheel steamer in New Orleans, Lousiana
$2,399
EXPLORE

New Orleans to Memphis

9 Day Itinerary aboard American Queen
  • Explore vibrant New Orleans
  • Experience the music of Memphis
  • Learn the history of Vicksburg
  • Explore Nottoway Plantation
Starts / Ends:
New Orleans / Memphis
Activities:
Archaeological Site Visits, River Cruises
Activity Level:
Relaxed
The Lower Mississippi River has stories to share – a legacy that flows from Memphis to the Gulf of Mexico. Embark on more than just a cruise, and return with more than memories: experience, understanding, an enlightened perspective. Explore the American South and discover all the great sights …
Cruise Details
0
Explore the fascinating Louisiana bayou
$5,099
EXPLORE

Roundtrip New Orleans

9 Day Itinerary aboard American Duchess
  • Admire the beauty of New Orleans
  • Indulge in New Orleans music
  • Experience life at Natchez
  • See preserved historic homes
Starts / Ends:
New Orleans / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Explore unique sites and attractions of the deep south on a river cruise round-trip from New Orleans. Uncover the treasures of Lower Mississippi River cities as you indulge in iconic Louisiana cuisine spiced with influences from the region’s diverse cultures. Visit historic estates and learn …
Cruise Details
0
View the iconic arch when you visit St. Louis, gateway to the west
$11,999
EXPLORE

America’s Great River

St. Paul to New Orleans - 15 Day Itinerary aboard Viking Mississippi
  • Explore St. Louis' arts scene
  • Enjoy American music styles
  • Learn Civil War history
  • Experience New Orleans' culture
  • Visit the Quad Cities
Starts / Ends:
St. Paul / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Village Visits
Activity Level:
Relaxed
Discover the history, natural beauty, and distinctive regional cultures of America's great river, the mighty Mississippi, on this 15-day cruise aboard Viking Mississippi. Set sail from St. Paul, Minnesota, and venture south toward New Orleans, Louisiana. Along the way, visit small towns and …
Cruise Details
0
View monuments from the Civil War in Mississippi
$11,199
EXPLORE

Minneapolis to New Orleans

16 Day Itinerary aboard American Duchess
  • Enjoy musical history in Memphis
  • Explore the arts in Minneapolis, MN
  • Discover St. Louis, Missouri
  • Admire the diversity of New Orleans
  • Learn about Civil War history
Starts / Ends:
Minneapolis / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Watch landscapes, cultures and even language transform as you cruise along the Mississippi river from Minneapolis to New Orleans aboard the American Duchess. Board this 16-day cruise to sail nearly the full length of the mighty Mississippi. Along the way, visit historic port cities and laid-back …
Cruise Details
0
Visit historic Memphis, Tennessee
$3,999
EXPLORE

Heart of the Delta

New Orleans to Memphis - 8 Day Itinerary aboard Viking Mississippi
  • Enjoy the music of Memphis
  • Get a taste of Cajun cuisine
  • Discover Civil War history
  • See the historic homes of Natchez
Starts / Ends:
New Orleans / Memphis
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Immerse yourself in the history and heritage of the Mississippi River on this 8-day voyage from New Orleans to Memphis. Soak up the rich French and Acadian cultures that infuse the Lower Mississippi, and be inspired by the stories of famed musicians and Civil Rights heroes. Savor delicious Cajun …
Cruise Details
0
$5,099
EXPLORE

New Orleans to Memphis

9 Day Itinerary aboard American Duchess
  • Discover St. Francisville
  • Experience the music of Memphis
  • Learn the history of Vicksburg
  • Explore vibrant New Orleans
Starts / Ends:
New Orleans / Memphis
Activities:
Archaeological Site Visits, River Cruises
Activity Level:
Relaxed
The Lower Mississippi River has stories to share – a legacy that flows from Memphis to the Gulf of Mexico. Embark on more than just a cruise, and return with more than memories: experience, understanding, an enlightened perspective. Explore the American South and discover all the great sights and …
Cruise Details
0
$3,599
EXPLORE

Louisville to St. Louis

9 Day Itinerary aboard American Countess
  • Taste famous Kentucky bourbon
  • Enjoy the music of Owensboro
  • Admire historic handicrafts
  • Explore vibrant St. Louis
Starts / Ends:
Louisville / St. Louis
Activities:
River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Board the American Countess riverboat and cruise through the heart of the American Midwest on this 9-day journey from Louisville, Kentucky to St. Louis, Missouri on the Ohio and Mississippi Rivers. Experience the laid-back, small-town hospitality of Kentucky ports such as Owensboro, where …
Cruise Details
0
Visit historic St. Louis
$2,799
EXPLORE

St. Louis to Minneapolis

9 Day Itinerary aboard American Countess
  • Explore the culture of St. Louis
  • See Mark Twains hometown, Hannibal
  • Relax in laid-back La Crosse
  • Admire local artwork in Red Wing
Starts / Ends:
St. Louis / Red Wing
Activities:
Archaeological Site Visits, River Cruises, Village Visits
Activity Level:
Relaxed
Explore the country and river that inspired Mark Twain, the pen name of the famed American novelist Samuel Clemens. From St. Louis, Missouri, cruise north along the magnificent Mississippi River towards Minneapolis. Explore port towns such as Hannibal, Missouri, the birthplace of Mark Twain, and …
Cruise Details
0
Explore historic New Orleans
$5,999
EXPLORE

Minneapolis to New Orleans

16 Day Itinerary aboard American Queen
  • Enjoy musical history in Memphis
  • Admire the diversity of New Orleans
  • Discover St. Louis, Missouri
  • Explore the arts in Minneapolis, MN
  • Learn about Civil War history
Starts / Ends:
Minneapolis / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Watch landscapes, cultures and even language transform as you cruise along the Mississippi river from Minneapolis to New Orleans aboard the American Queen. Board this 16-day cruise to sail nearly the full length of the mighty Mississippi. Along the way, visit historic port cities and laid-back …
Cruise Details
0
Wander through the historic French Quarter
$3,999
EXPLORE

New Orleans & Southern Charms

8 Day Itinerary aboard Viking Mississippi
  • Enjoy Cajun and Creole cuisine
  • Indulge in New Orleans' music
  • Learn the history of Vicksburg
  • See the historic homes of Natchez
Starts / Ends:
New Orleans / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
The Lower Mississippi overflows with charm, history and hospitality. Wander historic estates, and visit notable Civil War sites. Explore the bustling French-influenced port cities of New Orleans and Baton Rouge. Sway to the tempos of Dixieland jazz, gospel and blues. Savor gourmet Cajun and Creole …
Cruise Details
0
Explore historic New Orleans
$5,099
EXPLORE

Memphis to New Orleans

9 Day Itinerary aboard American Duchess
  • Explore the music of Memphis
  • Visit an Antebellum home
  • Learn the history of Vicksburg
  • Enjoy the beauty of Baton Rouge
Starts / Ends:
Memphis / New Orleans
Activities:
Archaeological Site Visits, Festival Visits, River Cruises, Urban Exploration
Activity Level:
Relaxed
The Lower Mississippi River has stories to share – a legacy that flows from Memphis to the Gulf of Mexico. Embark on more than just a cruise, and return with more than memories: experience, understanding, an enlightened perspective. Explore the American South and discover all the great sights …
Cruise Details
0
Memphis, Tennesse, USA downtown cityscape at dusk over Beale Street
$2,399
EXPLORE

Memphis to New Orleans

9 Day Itinerary aboard American Queen
  • Admire the diversity of New Orleans
  • Discover the cultures of the delta
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts / Ends:
New Orleans / Memphis
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
The Lower Mississippi River has stories to share – a legacy that flows from Memphis to the Gulf of Mexico. Embark on more than just a cruise, and return with more than memories: experience, understanding, an enlightened perspective. Explore the American South and discover all the great sights …
Cruise Details
0
Explore historic New Orleans
$2,499
EXPLORE

Roundtrip New Orleans

9 Day Itinerary aboard American Queen
  • Immerse yourself in New Orleans
  • Discover legendary Nottoway
  • Visit historic Civil War sites
  • Visit charming ports and cities
Starts / Ends:
New Orleans / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration
Activity Level:
Relaxed
Discover unique sites and attractions along the Mississippi River and admire the beauty of the world around you on a roundtrip river cruise from New Orleans. Uncover the treasures of Lower Mississippi River cities as you indulge in iconic Louisiana cuisine spiced with the cultural flavors of the …
Cruise Details
0
View a Civil War battlefields in Mississippi
$3,599
EXPLORE

Roundtrip New Orleans

9 Day Itinerary aboard American Countess
  • Admire the beauty of New Orleans
  • Indulge in New Orleans music
  • Experience life at Natchez
  • See preserved historic homes
Starts / Ends:
New Orleans / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Explore unique sites and attractions of the deep south on a river cruise round-trip from New Orleans. Uncover the treasures of Lower Mississippi River cities as you indulge in iconic Louisiana cuisine spiced with influences from the region’s diverse cultures. Visit historic estates and learn …
Cruise Details
0
Enjoy vibrant nightlife and live music
$5,599
EXPLORE

Memphis to St. Louis

(or reverse) - 9 Day Itinerary aboard American Duchess
  • Explore Memphis
  • Discover New Madrid
  • Experience Paducah's history
  • Visit Cape Girardeau
Starts / Ends:
Memphis / St. Louis
Activities:
River Cruises, Small Ship Cruises, Urban Exploration
Activity Level:
Relaxed
From Memphis to St. Louis, the Lower Mississippi River is loaded with stories to tell. From the legacies that line the Mississippi to the imaginative corners of Ohio, this 9-day riverboat tour promises a variety of enlightening encounters and unforgettable memories. Explore the seismic wonders of …
Cruise Details
0
$3,199
EXPLORE

New Orleans to Memphis

9 Day Itinerary aboard American Countess
  • Discover St. Francisville
  • Experience the music of Memphis
  • Learn the history of Vicksburg
  • Explore vibrant New Orleans
Starts / Ends:
New Orleans / Memphis
Activities:
Archaeological Site Visits, River Cruises
Activity Level:
Relaxed
The Lower Mississippi River has stories to share – a legacy that flows from Memphis to the Gulf of Mexico. Embark on more than just a cruise, and return with more than memories: experience, understanding, an enlightened perspective. Explore the American South and discover all the great sights …
Cruise Details
0
Memphis, Tennesse, USA downtown cityscape at dusk over Beale Street
$3,199
EXPLORE

Memphis to New Orleans

9 Day Itinerary aboard American Countess
  • Admire the diversity of New Orleans
  • Discover the cultures of the region
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts / Ends:
New Orleans / Memphis
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
The Lower Mississippi River has stories to share – a legacy that flows from Memphis to the Gulf of Mexico. Embark on more than just a cruise, and return with more than memories: experience, understanding, and an enlightened perspective. Explore the American South and discover all the great sights …
Cruise Details
0
1-18 of 32 Results

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