Mississippi River Tours in 2026

Discover America’s heartland on an 8-day Viking Mississippi cruise from Alton to Red Wing, exploring St. Louis, Hannibal, Burlington, the Quad Cities, Dubuque, and La Crosse. From Mark Twain’s hometown to the Mississippi River Museum, each stop offers a direct look into the nation’s past.

Set sail for 9 days aboard American Serenade from St. Paul to St. Louis. Walk through historic Summit Avenue, admire La Crosse from Grandad’s Bluff, explore Dubuque’s River Museum, and discover Mark Twain’s legacy in Hannibal. Experience curated onboard programs, live music, and the beauty of the Upper Mississippi’s diverse wildlife.

Cruise America's great river on this 15-day itinerary aboard Viking Mississippi. Journey from St. Paul, Minnesota to New Orleans, Louisiana and explore highlights of the mighty Mississippi River. Along the way, visit historic ports such as St. Louis, Memphis, Baton Rouge, and more.

Cruise the Mississippi River on a 16-day voyage aboard American Serenade. Visit La Crosse, Dubuque, Davenport, Hannibal, St. Louis, Memphis, Tunica, Vicksburg, Natchez, and Baton Rouge while exploring museums, riverfronts, historic landmarks, Civil War sites, and music destinations. Enjoy scenic cruising through the Upper and Lower Mississippi.

On this 8-day Mississippi Delta Explorer from New Orleans to Memphis aboard the Viking Mississippi, visit historic towns like Darrow, Natchez, and Vicksburg. Enjoy Cajun and Creole cuisine, Memphis barbecue, and explore the South’s rich history, culture, and music.

Explore the highlights of the Mississippi River on this 8-day cruise roundtrip from New Orleans aboard Viking Mississippi. Discover port cities such as St. Francisville, Darrow, Baton Rouge, Natchez, and Vicksburg to experience the diverse culture and rich history of the lower Mississippi region.

Embark on a 9-day cruise from New Orleans to Memphis aboard American Melody, exploring Southern culture and history with local guides. Enjoy enriching excursions, gourmet meals, daily cocktails, and captivating shows at historic sites like Vicksburg and Natchez.

Take an 8-day Viking Mississippi cruise through Memphis, Cape Girardeau, Paducah, Clarksville, and Nashville. Visit key cultural and historical sites, from music landmarks to Civil War history and regional museums.

Cruise on a 9-day voyage aboard American Melody along the Mississippi River. Visit Cleveland, Vicksburg, Natchez, Baton Rouge, and Oak Alley through included excursions featuring museums, Civil War sites, historic homes, and music heritage. This itinerary combines Mississippi River scenery with Southern history and culture.

The American Melody hosts this 8-day Mississippi River cruise from New Orleans. Explore historic plantations, Civil War sites, and charming towns. Immerse in the rich culture, cuisine, and music of the Deep South.

Sail from Pittsburgh to St. Louis on a 16-day Ohio River cruise aboard American Melody. Visit historic towns like Marietta, Cincinnati, Louisville, and Paducah. Discover museums, landmark sites, and cultural excursions while enjoying daily enrichment programs and scenic cruising.