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Top South America Trips & Tours in May 2026

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Discover South America in May 2026 on one of these 600 tours hand-selected by the travel experts at Adventure Life. Explore the best of during May 2026 as you enjoy Wildlife Viewing, Hiking, Snorkeling, Kayaking, and Village Visits. Prices for trips in May 2026 range from $54 to $381,349 for a vacation of 5 to 16 days. Choose any of the below 600 itineraries in May 2026 and customize it when you contact one of Adventure Life's expert South America trip planners.
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Uros Island - Floating island at the Titicaca
from $4,631
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Panoramic Peru

16 Day Itinerary
  • Discover Peru's 'Little Galapagos'
  • View the Nazca Lines with a flyover
  • Explore Colca Canyon
  • Visit the shores of Lake Titicaca
Starts / Ends
Lima / Lima
Activity Level
Relaxed
This 16-day tour highlights the best of Peru, including Islas Ballestas and Paracas, the Nazca Lines, Colca Canyon, the islands of Lake Titicaca, Cusco and the Lost City of the Incas--Machu Picchu. From the coast to the Andes to the Amazon jungle, this tour has a little bit of everything!
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Relax in the waters of Fernando de Noronha
from $1,481
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Fernando de Noronha

5 Day Itinerary
  • Hike to spectacular beaches
  • Snorkel and swim in Atlantic waters
  • Learn about conservation efforts
Activities
Snorkeling, Scuba Diving
Activity Level
Relaxed
Fernando de Noronha, an archipelago located off of Brazil's northwest coast, epitomizes the term 'island paradise.' Home to some of the world's most pristine, picturesque beaches, Fernando de Noronha is the perfect destination for travelers seeking an authentic Brazilian experience in a tropical setting unparalleled in beauty.
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Local woman at Lake Titicaca
from $3,196
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Highlights of Peru & Bolivia

14 Day Itinerary
  • Tour Cusco's largest open market
  • Visit Sun and Moon Islands
  • Discover Machu Picchu
  • Climb El Calvario for great views
Activity Level
Relaxed
In two weeks, travel through both Peru and Bolivia. Begin in Peru, visiting markets and ruin sites as you travel through the Sacred Valley to the lost city of Machu Picchu. Discover the birthplace of the Inca on Lake Titicaca. Finish your journey in La Paz, Bolivia and Moon Valley seeing the curious way erosion has shaped the landscape.
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Horseback Riding
from $3,437
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Ecuador Adventure

9 Day Itinerary
  • Bike down the slopes of Pinchincha
  • Explore Bellavista Cloud Forest
  • Horseback ride across the páramo
  • Zipline and hike in Mindo
Starts / Ends
Quito / Quito
Activities
Hacienda Visits
Activity Level
Moderate
Bike down the slopes of Pichincha Volcano, hike through dense, biodiverse cloud forest, zip-line over the forest canopy, hike, and ride horses through the high Andes near the active 19,347-foot high Cotopaxi Volcano on this exciting 9-day adventure tour of Ecuador.
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Fresh produce at a market
from $2,407
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Flavors of Peru

8 Day Itinerary
  • Savor Peruvian dishes in Barranco
  • Explore Chocomuseo and Pisco Museum
  • Witness Andean traditions
  • Explore the ruins of Machu Picchu
Starts / Ends
Lima / Cusco
Activity Level
Relaxed
Join this 8-day tour that takes you to Lima, Cusco, the Sacred Valley, and the citadel of Machu Picchu. Explore the culinary delights of Peru in Barranco, where you can taste traditional dishes like lomo saltado and causa. This is a relaxed, cultural-focused trip with an emphasis on the flavors and gastronomy of Peru.
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Atacama Desert
from $210
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Atacama Archaeological Tour

½ Day Itinerary
Starts / Ends
Atacama Desert / Atacama Desert
Activity Level
Relaxed
Explore in 2025 with a relaxed journey through the Andes and Atacama Desert. Enjoy easy archaeological visits and stunning landscapes with minimal effort. Perfect for comfort seekers, this trip blends culture and nature in , part of . Plan for 2026 too!
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sally lightfoot crab
from $4,150
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Southern Islands

5 Day Itinerary aboard Treasure of Galapagos
Starts / Ends
San Cristobal Airport / Baltra
Activity Level
Variable
This 5-day Southern Galapagos Islands cruise on the Treasure of the Galapagos yacht explores the islands of Santa Cruz, San Cristobal, Santa Fe and more.
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Laguna Colorada
from $4,060
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High Deserts of Bolivia & Chile

10 Day Itinerary
  • Explore Lake Titicaca
  • Uyuni Salt Desert in depth
  • Visit altiplanic lagoons
  • Discover the beauty of Atacama
Activities
Local Market Visits, Wildlife Viewing
Activity Level
Relaxed
Explore Bolivia and Chile on this 10-day adventure tour revealing an extreme geography of deserts, mountains, canyons, and lagoons. Visit Salar de Uyuni, Lake Titicaca, and the Atacama Desert while viewing breathtaking landscapes every step of the way! Starting in La Paz, Bolivia you'll journey to Tatio Geysers, the Valley of the Moon, and more.
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Watch the afternoon sunlight glow on the walls of Machu Picchu on your Peru tour
from $3,595
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Machu Picchu by Train with Luxury Hotels

7 Day Itinerary
  • Watch the sunrise over Machu Picchu
  • Explore Cusco with a local guide
  • Tour the ruins of Ollantaytambo
  • Visit a local textile market
Activity Level
Relaxed
Our mainstay Machu Picchu trip with luxury accommodations. We visit the most important Inca ruins such as Sacsayhuamán, Pisac, and Ollantaytambo, and we spend two days exploring the Lost City of Machu Picchu. This is an easy paced weeklong journey perfect for anyone with a sense of curiosity and adventure.
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Ushuaia, Argentina kayak adventure tour
from $369
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Lakes Off Road

1 Day Itinerary
  • Views the stunning Lago Escondido
  • Off-road journey via Andes Mt Range
  • Sample an Argentine lunch
Activity Level
Relaxed
This full-day trip from Ushuaia, Argentina lets you explore the Southern Andes Mountain Range on an off-road adventure. Explore the view of Lago Escondido (Hidden Lake), a little wonder that hides at the bottom of a valley, from Garibaldi Pass. Continue onward in a 4x4 vehicle through the forest and across rivers toward the shore of Fagnano Lake.
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Enjoying a mountain bike ride
from $5,772
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Sacred Valley & Lake Titicaca Multisport

12 Day Itinerary
  • Whitewater raft the Urubamba River
  • Bike past lakes, farms, & villages
  • Trek the Queñua Sundur Valley
  • Kayak around Lake Titicaca
Activities
Homestays, Camping
Activity Level
Moderate
This active 12-day tour through Peru blends exhilarating multi-sport adventures like whitewater rafting, kayaking, hiking, trekking, and mountain biking around Cusco & the Sacred Valley climaxing in an unforgettable trip to Machu Picchu. Then, travel south to Puno and go sea kayaking on Lake Titicaca visiting Amantani and Ticonata Islands.
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Brilliant blue water of Argentine lakes
from $6,639
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Discover Argentina

10 Day Itinerary
  • Visit Buenos Aires and Tigre Delta
  • Enjoy wine tasting in Mendoza
  • Explore Bariloche and Patagonia
Starts / Ends
Buenos Aires / Buenos Aires
Activities
Cooking Classes, Urban Exploration, Kayaking, Fishing
Activity Level
Relaxed
Enjoy a complete 10-day upscale tour discovering the best of Argentina. Dance the tango in Buenos Aires, float down the Tigre Delta, take a cooking class and go wine tasting in Mendoza. Explore the peaks and lakes of the high Andes hiking at a historical Estancia near Bariloche in Patagonia.
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Wines of Europe
from $5,846
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Taste of Argentina

9 Day Itinerary
  • Explore Salta's colorful markets
  • Visit a local family goat farm
  • Tour vineyards with an oenologist
  • Attend an Andean cooking class
Activity Level
Relaxed
Join this 9-day journey to discover the delicious local dishes and wines, as well as the inviting culture and landscape of northern Argentina -- a world apart from the country's chilly southern reaches!
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Puerto Madero in Buenos Aires
from $2,640
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Beautiful Buenos Aires & Iguazu Falls

Tour - 7 Day Itinerary
  • Experience an Argentine Tango show
  • Enjoy exploring Buenos Aires
  • Visit and discover Iguazu Falls
  • Explore Tigre Delta
Activities
Ziplining
Activity Level
Relaxed
Begin this week-long Argentina vacation in metropolitan Buenos Aires before traveling to Iguazu Falls, the world's largest waterfall system at the Argentine-Brazilian border. Enjoy the best Argentina has to offer with visits to local fruit markets at the Tigre Delta, ferry tours, tango shows and of course, Argentine steak & wine.
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Chilean vineyards
from $2,075
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Colchagua Valley Wine Escape

3 Day Itinerary
  • Enjoy horse ride at VIK winery
  • Trek across the Colchagua Valley
  • Visit the Lapostolle Winery
Starts / Ends
Santiago / Santiago
Activities
Wine Tasting, Village Visits, Horseback Riding
Activity Level
Relaxed
Sample some of Chile’s internationally renowned wines on this three-day getaway in the enchanting Colchagua Valley, exploring the vineyards in style via walking and horseback riding before spending the nights in luxury accommodations after full days of wine-induced decadence.
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Explore Easter Island
from $1,950
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Classic Easter Island Group tour

5 Day Itinerary
  • See the superb Moai Stone Statues
  • Admire spectacular ancient ruins
  • Discover beautiful volcanoes
Starts / Ends
Easter Island / Hotel Otai
Activities
Archaeological Site Visits, Hiking
Activity Level
Relaxed
Immerse yourself in the mystical culture, epic landscapes, and ocean views of legendary Easter Island. Visit the mysterious Moai statues, walk and drive around the island’s best natural and archeological sites, and learn more about this fascinating island!
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Sunset over Iguazu Falls
from $1,798
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Iguazu Falls & Argentine Rainforest

5 Day Itinerary
  • Explore the famous Iguazu Falls
  • Spot wildlife at Yacutinga Lodge
  • Float the San Francisco River
Activities
Wilderness Lodge Exploration, Rainforest Exploration
Activity Level
Relaxed
Experience the world's largest waterfall system - Iguazu Falls - on this amazing 5-day Argentina vacation. Take the "most beautiful thousand meter walk in the world" overlooking the Falls, then search for rainforest wildlife as you spend three nights at Yacutinga Lodge experiencing the subtropical rainforest straddling the Argentina-Brazil border.
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Whitewater rafting adventure on Chile's Rio Futaleufu
from $900
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Lakes District Adventure

4 Day Itinerary
  • Enjoy rafting on the Petrohue River
  • Discover Perez National Park
  • Bike along Lake Llanquihue
Activities
Whitewater Rafting, Biking
Activity Level
Moderate
Explore the Chile Lakes District regions, with its beautiful natural scenery and opportunities for adventure. Enjoy nature hikes, whitewater rafting, biking, and a taste of the Welsh local culture of Puerto Varas. Combine this short extension with other Chile tours and extensions, or the Chiloe Island Adventure!
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