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Top Mississippi River Trips & Tours in September 2024

Travel made your way
New Orleans
Sean Pavone
Visit the famed Bourbon Street
St Louis
Sean Pavone
View the iconic arch when you visit St. Louis, gateway to the west
Vicksburg
Michael Warren
View a Civil War battlefields in Mississippi
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Discover Mississippi River in September 2024 on one of these 9 tours hand-selected by the travel experts at Adventure Life. Explore the best of New Orleans, Memphis, Natchez, Vicksburg, and Nottoway during September 2024 as you enjoy river cruises, cruises, cultural, archaeological site visits, and village visits. Prices for trips in September 2024 range from $2,199 to $29,999 for a vacation of 9 to 15 days. Choose any of the below 9 amazing itineraries in September 2024 and customize it to make it your own with the help of one of Adventure Life's expert Mississippi River trip planners.
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New Orleans paddlewheel steamer in New Orleans, Lousiana
$3,319
EXPLORE

New Orleans to Memphis

9 Day Itinerary aboard American Queen
  • Explore vibrant New Orleans
  • Experience the music of Memphis
  • Learn the history of Vicksburg
  • Explore Nottoway Plantation
Starts / Ends:
New Orleans / Memphis
Activities:
Archaeological Site Visits, River Cruises
Activity Level:
Relaxed
The Lower Mississippi River has stories to share – a legacy that flows from Memphis to the Gulf of Mexico. Embark on more than just a cruise, and return with more than memories: experience, understanding, an enlightened perspective. Explore the American South and discover all the great sights …
Cruise Details
0
View the iconic arch when you visit St. Louis, gateway to the west
$12,499
EXPLORE

America’s Great River

St. Paul to New Orleans - 15 Day Itinerary aboard Viking Mississippi
  • Explore St. Louis' arts scene
  • Enjoy American music styles
  • Learn Civil War history
  • Experience New Orleans' culture
  • Visit the Quad Cities
Starts / Ends:
St. Paul / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Village Visits
Activity Level:
Relaxed
Discover the history, natural beauty, and distinctive regional cultures of America's great river, the mighty Mississippi, on this 15-day cruise aboard Viking Mississippi. Set sail from St. Paul, Minnesota, and venture south toward New Orleans, Louisiana. Along the way, visit small towns and …
Cruise Details
0
$6,119
EXPLORE

New Orleans to Memphis

9 Day Itinerary aboard American Duchess
  • Discover St. Francisville
  • Experience the music of Memphis
  • Learn the history of Vicksburg
  • Explore vibrant New Orleans
Starts / Ends:
New Orleans / Memphis
Activities:
Archaeological Site Visits, River Cruises
Activity Level:
Relaxed
The Lower Mississippi River has stories to share – a legacy that flows from Memphis to the Gulf of Mexico. Embark on more than just a cruise, and return with more than memories: experience, understanding, an enlightened perspective. Explore the American South and discover all the great sights and …
Cruise Details
0
Visit historic St. Louis
$4,219
EXPLORE

St. Louis to Minneapolis

9 Day Itinerary aboard American Countess
  • Explore the culture of St. Louis
  • See Mark Twains hometown, Hannibal
  • Relax in laid-back La Crosse
  • Admire local artwork in Red Wing
Starts / Ends:
St. Louis / Red Wing
Activities:
Archaeological Site Visits, River Cruises, Village Visits
Activity Level:
Relaxed
Explore the country and river that inspired Mark Twain, the pen name of the famed American novelist Samuel Clemens. From St. Louis, Missouri, cruise north along the magnificent Mississippi River towards Minneapolis. Explore port towns such as Hannibal, Missouri, the birthplace of Mark Twain, and …
Cruise Details
0
Explore historic New Orleans
$6,119
EXPLORE

Memphis to New Orleans

9 Day Itinerary aboard American Duchess
  • Explore the music of Memphis
  • Visit an Antebellum home
  • Learn the history of Vicksburg
  • Enjoy the beauty of Baton Rouge
Starts / Ends:
Memphis / New Orleans
Activities:
Archaeological Site Visits, Festival Visits, River Cruises, Urban Exploration
Activity Level:
Relaxed
The Lower Mississippi River has stories to share – a legacy that flows from Memphis to the Gulf of Mexico. Embark on more than just a cruise, and return with more than memories: experience, understanding, an enlightened perspective. Explore the American South and discover all the great sights …
Cruise Details
0
Memphis, Tennesse, USA downtown cityscape at dusk over Beale Street
$3,319
EXPLORE

Memphis to New Orleans

9 Day Itinerary aboard American Queen
  • Admire the diversity of New Orleans
  • Discover the cultures of the delta
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts / Ends:
New Orleans / Memphis
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
The Lower Mississippi River has stories to share – a legacy that flows from Memphis to the Gulf of Mexico. Embark on more than just a cruise, and return with more than memories: experience, understanding, an enlightened perspective. Explore the American South and discover all the great sights …
Cruise Details
0
$4,219
EXPLORE

New Orleans to Memphis

9 Day Itinerary aboard American Countess
  • Discover St. Francisville
  • Experience the music of Memphis
  • Learn the history of Vicksburg
  • Explore vibrant New Orleans
Starts / Ends:
New Orleans / Memphis
Activities:
Archaeological Site Visits, River Cruises
Activity Level:
Relaxed
The Lower Mississippi River has stories to share – a legacy that flows from Memphis to the Gulf of Mexico. Embark on more than just a cruise, and return with more than memories: experience, understanding, an enlightened perspective. Explore the American South and discover all the great sights …
Cruise Details
0
Memphis, Tennesse, USA downtown cityscape at dusk over Beale Street
$4,219
EXPLORE

Memphis to New Orleans

9 Day Itinerary aboard American Countess
  • Admire the diversity of New Orleans
  • Discover the cultures of the region
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts / Ends:
New Orleans / Memphis
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
The Lower Mississippi River has stories to share – a legacy that flows from Memphis to the Gulf of Mexico. Embark on more than just a cruise, and return with more than memories: experience, understanding, and an enlightened perspective. Explore the American South and discover all the great sights …
Cruise Details
0
Memphis, Tennesse, USA downtown cityscape at dusk over Beale Street
$4,219
EXPLORE

Memphis to New Orleans

9 Day Itinerary aboard American Countess
  • Admire the diversity of New Orleans
  • Discover the cultures of the region
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts / Ends:
New Orleans / Memphis
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
The Lower Mississippi River has stories to share – a legacy that flows from Memphis to the Gulf of Mexico. Embark on more than just a cruise, and return with more than memories: experience, understanding, and an enlightened perspective. Explore the American South and discover all the great …
Cruise Details
0
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