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Mississippi River, St. Paul Minnesota

Mississippi River Wildlife Viewing Trips & Safaris

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Explore the amazing wildlife of Mississippi River on one of these 11 tours to Memphis, Baton Rouge, Natchez, Vicksburg, and New Orleans in 2026-2027. Prices for a wildlife viewing trip in Mississippi River range from $4,295 to $22,170 for a trip of 8 to 16 days. Choose one of the below 11 Mississippi River wildlife safari tours and make it your own unique experience with the help of one of Adventure Life's expert Mississippi River trip planners.
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    • Mississippi River
Visit historic St. Louis
from $5,499
EXPLORE

Heartland of America

Missouri to Minnesota - 8 Day Itinerary aboard Viking Mississippi
  • Walk Mark Twain’s Hannibal
  • Explore John Deere innovations
  • Explore historic Burlington charm
  • Explore ancient mound builders
Starts / Ends
St. Louis / St. Paul
Activities
Hiking
Activity Level
Variable
Discover America’s heartland on an 8-day Viking Mississippi cruise from Alton to Red Wing, exploring St. Louis, Hannibal, Burlington, the Quad Cities, Dubuque, and La Crosse. From Mark Twain’s hometown to the Mississippi River Museum, each stop offers a direct look into the nation’s past.
Cruise Details
0
Vibrant Sunset with St. Paul City Skyline and Mississippi Riverfront
from $5,635
Savings
EXPLORE

Upper Mississippi River

St. Paul, MN - St. Louis, MO - 9 Day Itinerary aboard American Serenade
  • Tour historic Summit Avenue
  • Explore Dubuque River Museum
  • Experience John Deere Pavilion
  • Visit Mark Twain’s boyhood home
Starts / Ends
St. Paul / St. Louis
Activities
Urban Exploration, Biking, Wine Tasting
Activity Level
Variable
Set sail for 9 days aboard American Serenade from St. Paul to St. Louis. Walk through historic Summit Avenue, admire La Crosse from Grandad’s Bluff, explore Dubuque’s River Museum, and discover Mark Twain’s legacy in Hannibal. Experience curated onboard programs, live music, and the beauty of the Upper Mississippi’s diverse wildlife.
Cruise Details
0
Vibrant Sunset with St. Paul City Skyline and Mississippi Riverfront
from $12,620
Savings
EXPLORE

Grand Heartland Cruise

St. Paul to New Orleans - 16 Day Itinerary aboard American Serenade
  • Cruise Mississippi River scenery
  • Discover Davenport museums
  • Visit Gateway Arch landmark
  • Tour Vicksburg battlefields
Starts / Ends
St. Paul / New Orleans
Activities
Local Market Visits
Activity Level
Variable
Cruise the Mississippi River on a 16-day voyage aboard American Serenade. Visit La Crosse, Dubuque, Davenport, Hannibal, St. Louis, Memphis, Tunica, Vicksburg, Natchez, and Baton Rouge while exploring museums, riverfronts, historic landmarks, Civil War sites, and music destinations. Enjoy scenic cruising through the Upper and Lower Mississippi.
Cruise Details
0
Enjoy the colorful architecture of New Orleans
from $5,275
Savings
EXPLORE

Lower Mississippi River Cruise

New Orleans - Memphis - 9 Day Itinerary aboard American Melody
  • Explore New Orleans lively culture
  • Discover Oak Alley with landscapes
  • Discover Baton Rouge
  • Visit Graceland Memphis
Starts / Ends
New Orleans / Memphis
Activities
Wildlife Viewing, Archaeological Site Visits, Village Visits, Cooking Classes
Activity Level
Variable
Embark on a 9-day cruise from New Orleans to Memphis aboard American Melody, exploring Southern culture and history with local guides. Enjoy enriching excursions, gourmet meals, daily cocktails, and captivating shows at historic sites like Vicksburg and Natchez.
Cruise Details
0
Vicksburg Battlefield overlooking the Mississippi River
from $4,925
Savings
EXPLORE

Lower Mississippi River Cruise

New Orleans - Memphis - 9 Day Itinerary aboard American Heritage
  • Admire the diversity of New Orleans
  • Visit Oak Alley mansion and avenue
  • Discover Baton Rouge's landmarks
  • Enjoy the music of Memphis
Starts / Ends
New Orleans / Memphis
Activity Level
Variable
Cruise aboard American Heritage on a 9-day cruise from New Orleans to Memphis along the Mississippi River. Visit Oak Alley, Baton Rouge, Natchez, Vicksburg, and Cleveland. Explore historic plantations, Civil War sites, blues landmarks, museums, and riverfront towns while experiencing the culture and history of the American South.
Cruise Details
0
View monuments from the Civil War in Mississippi
from $4,610
Savings
EXPLORE

Lower Mississippi River Cruise

Memphis - New Orleans - 9 Day Itinerary aboard American Heritage
  • Admire the diversity of New Orleans
  • Discover the cultures of the delta
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts / Ends
Memphis / New Orleans
Activity Level
Variable
Embark on a 9-day cruise aboard American Heritage from Memphis to New Orleans along the Lower Mississippi River. Visit Cleveland, Vicksburg, Natchez, Baton Rouge, and Oak Alley. Explore Civil War landmarks, historic homes, museums, plantations, and Louisiana wetlands while discovering the history, music, and culture of the American South.
Cruise Details
0
Explore beautiful Nashville
from $5,499
EXPLORE

Nashville, Memphis & the Cumberland

Memphis to Nashville - 8 Day Itinerary aboard Viking Mississippi
  • Discover Memphis blues roots
  • See Paducah murals
  • Walk historic Clarksville streets
  • Cruise Tennessee River scenery
Starts / Ends
Memphis / Nashville
Activity Level
Variable
Take an 8-day Viking Mississippi cruise through Memphis, Cape Girardeau, Paducah, Clarksville, and Nashville. Visit key cultural and historical sites, from music landmarks to Civil War history and regional museums.
Cruise Details
0
Memphis, Tennesse, USA downtown cityscape at dusk over Beale Street
from $5,275
Savings
EXPLORE

Lower Mississippi River Cruise

Memphis - New Orleans - 9 Day Itinerary aboard American Symphony
  • Explore Rosalie Mansion and Natchez
  • Visit Baton Rouge landmarks
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts / Ends
Memphis / New Orleans
Activity Level
Variable
Experience a 9-day cruise aboard American Symphony from Memphis to New Orleans, discovering historic sites, Civil War stories, and charming towns along the Mississippi River. Experience rich history, music, and southern hospitality.
Cruise Details
0
Visit Louisiana's capital city of Baton Rouge
from $4,295
Savings
EXPLORE

Lower Mississippi River Cruise

Memphis - New Orleans - 9 Day Itinerary aboard American Splendor
  • Cruise Louisiana wetlands
  • Explore downtown Natchez
  • Tour Rosalie Mansion
  • Visit Vicksburg National Military
Starts / Ends
Memphis / New Orleans
Activity Level
Variable
Experience a 9-day cruise aboard American Splendor from Memphis to New Orleans, discovering historic sites, Civil War stories, and charming towns along the Mississippi River. Experience rich history, music, and southern hospitality.
Cruise Details
0
Explore the rivers of America
from $5,275
Savings
EXPLORE

Lower Mississippi River Cruise

Memphis - New Orleans - 9 Day Itinerary aboard American Melody
  • Tour Vicksburg battlefield
  • Explore Baton Rouge
  • Visit Oak Alley Estate
  • Enjoy Mississippi River cruising
Starts / Ends
Memphis / New Orleans
Activity Level
Variable
Cruise on a 9-day voyage aboard American Melody along the Mississippi River. Visit Cleveland, Vicksburg, Natchez, Baton Rouge, and Oak Alley through included excursions featuring museums, Civil War sites, historic homes, and music heritage. This itinerary combines Mississippi River scenery with Southern history and culture.
Cruise Details
0
View the iconic arch when you visit St. Louis, gateway to the west
from $9,920
Savings
EXPLORE

Grand Ohio River Cruise

Pittsburgh to St. Louis - 16 Day Itinerary aboard American Melody
  • Explore historic Marietta, Ohio
  • Explore Maysville’s Railroad
  • Visit Louisville’s Churchill Downs
  • Tour Paducah’s wall murals
Starts / Ends
Pittsburgh / St. Louis
Activity Level
Variable
Sail from Pittsburgh to St. Louis on a 16-day Ohio River cruise aboard American Melody. Visit historic towns like Marietta, Cincinnati, Louisville, and Paducah. Discover museums, landmark sites, and cultural excursions while enjoying daily enrichment programs and scenic cruising.
Cruise Details
0
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Franny Friesz Adventure Life employee profile
Franny F.
New Orleans paddlewheel steamer in New Orleans, Lousiana
Mississippi River

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