Top Panama Tours & Cruises in 2027

Experience a 10-day expedition from Callao (Lima), Peru to Colon, Panama aboard MV Discoverer. Explore ancient archaeological sites, Ecuador’s Pacific coast, Colombia’s biodiverse rainforests, and the engineering marvel of the Panama Canal while enjoying wildlife encounters, cultural discoveries, and enriching days at sea.

Set sail on a 10-day cruise aboard the Le Bellot to explore the stunning Caribbean, including the vibrant towns and rich history of Panama and Colombia. Swim in turquoise waters and snorkel in marine reserves while discovering unique cultures and ecosystems.

Join a 14-day cruise on the Scenic Eclipse II along South America's Pacific coast, starting in UNESCO-listed Valparaiso. Explore diverse wildlife, historic sites in Peru and Ecuador, and conclude in Panama’s Darien National Park, a UNESCO biosphere reserve.

This Panama City one-day tour takes you on the incredible journey from the Atlantic Ocean all the way to the Pacific Ocean, traversing two impressive locks via the manmade wonder that is the Panama Canal.

Climb aboard and experience the "Eighth Wonder of the World" first hand as you transit through the Miraflores Locks to the Pacific Ocean.

Tour Panama City with a local guide, well versed in the history of the area. See a transit of the Panama canal and tour Casco Antiguo where the pirate Henry Morgan waged his attack in 1671.

Visit Barro Colorado Island while in the Panama City with a boat ride in Gatún Lake. Enjoy a day exploring the Smithsonian Tropical Research Institute and learn about the current studies underway. This man-made island was created when the canal was flooded preserving a breathtaking array of diverse wildlife and jungle on the tiny island.

Drive from Panama City to El Valle: hike, zipline above El Macho Falls, explore the market, enjoy lunch & thermal pools.

Visit Aguas Clara Visitor Center for stunning Gatun Lake views and marvel at the historic San Lorenzo Fort. Explore scenic landscapes, rich wildlife, and Panama Canal expansion highlights in one action-packed day.

Experience native Panamanian culture deep in the Chagres rainforest. Visit with the people of the Embera Dura community and hike through the jungle with your guide.

Enjoy dinner and a show with this evening event full of the sights and smells of Panamanian tradition.