Have questions? We're here.
Snorkeling among the coral reef system

Panama Cruises

Travel made your way
Talk with an expert
Customize any aspect of your Panama trip. 1.406.541.2677
Help Me Plan My Trip
Filter (26 Results)
  • Start Date
    OR, More specific start
  • Length
    to
  • Price
    to
  • Activity Level
  • Experiences
  • Activities
  • Ship
  • Destinations
    • Panama
Panama City's Bridge of the Americas
$6,895
Save $400
EXPLORE

Costa Rica & Panama - Canal, Culture, Adventure

San Jose to Panama City - 11 Day Itinerary aboard Safari Voyager
  • Look for Mogue River´s wildlife
  • Wildlife viewing in Darién
  • Night transit on the Panamá Canal
  • Visit Granito de Oro islet
Activities:
Hiking, Kayaking, Photography Seminars, Small Ship Cruise, Snorkeling, Stand Up Paddle Board, Whale Watching, Wildlife Viewing
Activity Level:
Relaxed
Sail between two seas exploring two national parks, one wildlife refuge, and a conservation area on this 11-day cruise to Costa Rica and Panama. Witness the amazing wildlife of Manuel Antonio National Park, and discover the Osa Conservation Area´s abundant biodiversity including monkeys, …
Cruise Details
0
A monkey clings to the tree
$6,895
Save $400
EXPLORE

Costa Rica & Panama - Canal, Culture, Adventure

Panama City to San Jose - 11 Day Itinerary aboard Safari Voyager
  • Look for Mogue River´s wildlife
  • Wildlife viewing in Darién
  • Night transit on the Panamá Canal
  • Visit Granito de Oro islet
Starts/ Ends in:
Panama City / San Jose
Activities:
Hiking, Kayaking, Photography Seminars, Small Ship Cruise, Snorkeling, Stand Up Paddle Board, Whale Watching, Wildlife Viewing
Activity Level:
Relaxed
Sail between two seas exploring two national parks, one wildlife refuge, and a conservation area on this 11-day cruise to Costa Rica and Panama. Witness the amazing wildlife of Manuel Antonio National Park, and discover the Osa Conservation Area´s abundant biodiversity including monkeys, …
Cruise Details
0
Macaw in the jungle
$5,595
Savings
EXPLORE

Unveiled Wonders: Panama and Costa Rica

8 Day Itinerary aboard Safari Voyager
  • Cruise among the Gulf of Panama
  • Visit Manuel Antonio National Park
  • Explore the Curú National Refuge
  • Hike in a birder´s paradise
  • Enjoy San José or Panamá City
  • Search for untamed wildlife
Activities:
Kayaking, Small Ship Cruise, Snorkeling, Stand Up Paddle Board, Wildlife Viewing
Activity Level:
Relaxed
Uncover the wonder of jungles, mangroves, national parks, preserves, and the Panama Canal - this 8-day voyage has it all to make you adventure unforgettable. From Panama City, transit from ocean to ocean along the 48-mile Panamá Canal, truly a marvel of engineering and human tenacity. Travel …
Cruise Details
0
Blue water and lush rain forest in Panama
$4,600
Savings
EXPLORE

Natural and Cultural History in Central America

8 Day Itinerary aboard Le Champlain
  • Explore the Curú Wildlife Refuge
  • Discover the San Blas Islands
  • Encounters with the indigenous
  • Visit the Darien National Park
Starts/ Ends in:
Puerto Caldera / Colon
Activities:
Small Ship Cruise, Village Visit, Wildlife Viewing
Activity Level:
Relaxed
Your journey inCentral Americastarts with a visit to theManuel Antonio National Park and the CurúWildlife Refuge.Deep inside the tropical rainforest you may be lucky enough to see multicoloured birds, monkeys, and iguanas. Then sail on to the magnificentDarien National Parkin Panama. This …
Cruise Details
0
Friendly Sloth
$2,190
EXPLORE

Treasures of Costa Rica & Panama: Puerto Caldera to Panama City

8 Day Itinerary aboard Panorama
  • Explore Manuel Antonio Reserve
  • Discover Casa Orquidea's flowers
  • Snorkel and swim in crystal waters
  • Visit the Embera indigenous group
Starts/ Ends in:
Puerto Caldera / Flamenco Marina
Activities:
Rainforest Exploration, Small Ship Cruise, Snorkeling, Village Visit, Wildlife Viewing
Activity Level:
Relaxed
Experience a harmonious balance between conventional cruising and private yachting, along with an exciting voyage of discovery along the Pacific Ocean coastline of Costa Rica. Explore the Nature Reserves and National Parks of Isla Coiba and Manuel Antonio, witness life in the Darrien Jungle, and …
Cruise Details
0
Panama adventure. Snorkeling!
$2,190
EXPLORE

Crossing the Panama Canal: Costa Rica to Panama

Puerto Caldera - Colon - 8 Day Itinerary aboard Panorama
  • Explore the stunning Manuel Antonio
  • Tour Casa Orquidea's flowers
  • Discover the forest and animal life
  • Cross to the Panama Canal
Starts/ Ends in:
Puerto Caldera / Colon
Activities:
Small Ship Cruise, Snorkeling, Village Visit, Wildlife Viewing
Activity Level:
Relaxed
Experience a harmonious balance between conventional cruising and private yachting, along with an exciting voyage of discovery along the Pacific Ocean coastline of Costa Rica. Explore the Nature Reserves and National Parks of Isla Coiba and Manuel Antonio, witness life in the Darrien Jungle, and …
Cruise Details
0
Trekking through Corcovado National Park in Costa Rica.
$6,380
EXPLORE

Costa Rica & the Panama Canal

8 Day Itinerary aboard National Geographic Quest
  • Observe animals in their habitat
  • Kayak through magical mangroves
  • Transit the historical Panama Canal
  • Explore Gulf of Panama beaches
Activities:
Horseback Riding, Kayaking, Small Ship Cruise, Snorkeling, Stand Up Paddle Board, Wildlife Viewing
Activity Level:
Relaxed
Join the National Geographic Quest onthis 8-dayexpedition to Costa Rica and the Panama Canal.Discover diverse wilderness and jungle wildlife coupled with an in-depth crossing of the Panama Canal, a marvel of engineering, and gain special access to the Smithsonian Tropical Research Institute in the …
Cruise Details
0
Blue water and lush rain forest in Panama
$5,990
EXPLORE

Exploring the Caribbean Coast

8 Day Itinerary aboard National Geographic Quest
  • Transit the Panama Canal
  • Discover Colombia's wilderness
  • Visit Guna Yala
  • Explore pristine beaches & jungles
Starts/ Ends in:
Panama City / Cartagena
Activities:
Hiking, Rainforest Exploration, Small Ship Cruise, Snorkeling, Village Visit
Activity Level:
Relaxed
Discover an astonishing trove of natural and cultural treasures as you navigate the Caribbean coast of Panama and Colombia aboard theNational Geographic Quest. Hike into dense rainforests that harbor extraordinary biodiversity, glide through little-explored inlets by Zodiac and kayak, and meet the …
Cruise Details
0
Blue water and lush rain forest in Panama
$4,995
Save $400
EXPLORE

Colombia & Panama—Coral, Jungles, Canal

Panama City to Cartagena - 8 Day Itinerary aboard Safari Voyager
  • Explore the Gulf of Panama
  • Tour Cartagena
  • Learn more about the locals
  • Discover the stunning Darien Jungle
Starts/ Ends in:
Panama City / Cartagena
Activities:
Hiking, Kayaking, Rainforest Exploration, Small Ship Cruise, Snorkeling, Village Visit, Wildlife Viewing
Activity Level:
Relaxed
Visit tropical rainforests, biodiverse jungles, and lush tangled mangroves during this 8-day Central America cruise. Trek and paddle under the watchful eyes of macaws while howler monkeys do acrobatics in the treetops and reef fish swim alongside you.Explore Panamá’s Isla …
Cruise Details
0
Darien Jungle of Panama
$4,995
Save $400
EXPLORE

Colombia & Panama—Coral, Jungles, Canal

Cartagena to Panama City - 8 Day Itinerary aboard Safari Voyager
  • Discover the Darien Jungle
  • Visit the historic Cartagena
  • Admire incredible wildlife
  • Enjoy unique kayak adventures
Starts/ Ends in:
Cartagena / Panama City
Activities:
Hiking, Kayaking, Rainforest Exploration, Small Ship Cruise, Snorkeling, Village Visit, Wildlife Viewing
Activity Level:
Relaxed
Visit tropical rainforests, biodiverse jungles, and lush tangled mangroves during this 8-day Central America cruise. Trek and paddle under the watchful eyes of macaws while howler monkeys do acrobatics in the treetops and reef fish swim alongside you. Explore Panamá’s Isla …
Cruise Details
0
Manuel Antonio National Park
$3,490
EXPLORE

National Parks and Panama Canal

Puerto Caldera to Colón - 8 Day Itinerary aboard Le Dumont-d'Urville
  • Discover San Blas Islands
  • Sail through the Panama Canal
  • Encounters with Emberas tribe
  • Relax and take in the sun onboard
Starts/ Ends in:
Puerto Caldera / Colon
Activities:
Small Ship Cruise, Snorkeling, Spa & Relaxing, Wildlife Viewing
Activity Level:
Relaxed
Your journey to Central America starts with a visit to two superb Costa Rican national parks: the Carara National Parkand the Manuel Antonio National Park.Deep inside the tropical rainforest or under the rainforest canopy, you may be lucky enough to see multicolored birds, monkeys, crocodiles, and …
Cruise Details
0
Playa Manuel Antonio
$2,190
EXPLORE

Treasures of Panama & Costa Rica

Panama to Costa Rica - 8 Day Itinerary aboard Panorama
  • Visit the famous Panama Canal
  • Swim & snorkel at the Pearl Islands
  • Discover beautiful Casa Orquideas
  • Explore Isla Coiba & Manuel Antonio
Starts/ Ends in:
Panama City / Puerto Caldera
Activities:
Rainforest Exploration, Small Ship Cruise, Snorkeling, Wildlife Viewing
Activity Level:
Relaxed
Discover rarely visited ports of call, hidden coves, crystal blue waters, ancient history, and rich flora and fauna as you travel from Flamenco Marina Panama City, Panama to Puerto Caldera, Costa Rica. Discover why the locals have been called the happiest people in the world.Costa …
Cruise Details
0
Panama City's Bridge of the Americas
$2,590
EXPLORE

Crossing the Panama Canal: Panama to Costa Rica

Colon - Puerto Caldera - 8 Day Itinerary aboard Panorama
  • Visit the famous Panama Canal
  • Swim & snorkel at the Pearl Islands
  • Discover beautiful Casa Orquideas
  • Explore Isla Coiba & Manuel Antonio
Starts/ Ends in:
Colon / Puerto Caldera
Activities:
Rainforest Exploration, Small Ship Cruise, Snorkeling, Wildlife Viewing
Activity Level:
Relaxed
Discover rarely visited ports of call, hidden coves, crystal blue waters, ancient history, and rich flora and fauna as you travel from Colon, Panama to Puerto Caldera, Costa Rica. Discover why the locals have been called the happiest people in the world.Costa Rica'sabundant ecotourism treasures …
Cruise Details
0
Gatun Lock of the Panama Canal
$4,160
Savings
EXPLORE

Panama Canal: Panama to Antigua

15 Day Itinerary aboard Royal Clipper
  • Transit the historic Panama Canal
  • Enjoy Grenada's unique aromas
  • Discover Dutch colonial Curacao
  • Swim in paradise in Bonaire
Activities:
Sailing Schooner, Small Ship Cruise, Snorkeling, Wildlife Viewing
Activity Level:
Relaxed
Royal Clipper takes you to the seas for a stunning adventure packed with incredible experiences starting at the charming port town of Bridgetown, Barbados. Scour the streets of the UNESCO-listed cities of Cartagena de Indias, Colombia, and Willemstad, Curaçao. Swim in the protected, …
Cruise Details
0
Colorful harbor of Bonaire
$12,885
EXPLORE

Philipsburg to Puntarenas

16 Day Itinerary aboard Sea Cloud Spirit
  • View a tropical paradise Grenada
  • Immerse in traditions and culture
  • Transit the famous Panama Canal
  • Explore spectacular Costa Rica
Starts/ Ends in:
Philipsburg / Quepos
Activities:
Sailing Schooner, Small Ship Cruise, Snorkeling, Village Visit
Activity Level:
Relaxed
Fall in love with the crystal waters of the Caribbean, Panama and Costa Rica on this 16-day cruise aboard the Sea Cloud Spirit. Begin your exciting journey in Philipsburg, St. Maarten. Enjoy the tropical scenery of the best diving and snorkeling spots in the Carribean. Explore the colonial center …
Cruise Details
0
Road along coastline of Valparaiso
$6,000
EXPLORE

Expedition Cruise from Chile to Costa Rica

17 Day Itinerary aboard Ocean Victory
  • Admire historic Coquimbo
  • Marvel at the Atacama desert
  • See the ruins of Chan Chan
  • Look for incredible wildlife
Starts/ Ends in:
Valparaiso / Golfito
Activities:
Small Ship Cruise, Urban Exploration, Wildlife Viewing
Activity Level:
Relaxed
Cruise Details
0
Guayaquil Street View
$6,250
Savings
EXPLORE

Treasures of Central America

Guayaquil to Colon - 14 Day Itinerary aboard Le Boreal (CDP)
  • Visit the pyramids of Tikal
  • Discover Costa Rica's National Park
  • Observe unique tropical wildlife
  • View exceptional architecture
Starts/ Ends in:
Guayaquil / Colon
Activities:
Hiking, Rainforest Exploration, Small Ship Cruise, Wildlife Viewing
Activity Level:
Relaxed
FromPuerto Quetzal, visitAntigua Guatemala. Listed as aUNESCO World Heritage Site, this city, overlooked by majestic volcanoes, is often considered to be the country’s most beautiful. TheLeBoréalstops inQuepos, the gateway to one ofCosta Rica’s finest natural treasures, theManuel …
Cruise Details
0
Arenal Volcano
$10,840
EXPLORE

Panama to Costa Rica: Monteverde, Arenal, and Tortuguero

Panama to Costa Rica - 15 Day Itinerary aboard National Geographic Quest
  • Snorkel Isla Coiba's reefs
  • Walk Arenal Volcano's bridges
  • Hike in mist-shrouded Monteverde
  • Explore remote Tortuguero
  • Taste exclusive handmade chocolate
Activities:
Horseback Riding, Kayaking, Land & Sea, Small Ship Cruise, Snorkeling, Spa & Relaxing, Stand Up Paddle Board, Wildlife Viewing
Activity Level:
Relaxed
Join the National Geographic Quest on this extraordinary, holistic expedition - experience all the wildness and beauty of Costa Rica and Panama on a sweeping 15-day adventure. Transit the historical Panama Canal, with an exclusive visit to the Smithsonian Tropical Research Institute at Barro …
Cruise Details
0
1-18 of 26 Results

Panama Travel Guide

Favorite Panama Tours & Cruises

Top Panama Travel Destinations

Panama Trips by Departure Date

Panama Trips by Duration

Why Travel With Adventure Life

More Reasons

Recognized By

All News