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Top Panama Tours & Cruises in 2027

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Discover the best the world has to offer with Adventure Life’s expert-curated Panama tours 2027. From Panama City, Panama Canal, Colon, Balboa, and Bocas del Toro to hidden gems off the beaten path, our 27 top-rated itineraries take you deep into Panama’s breathtaking landscapes. Guided by bilingual experts, these immersive experiences cater to adventurers seeking unique journeys in small groups or customizable private tours.

Choose from a variety of 5 to 13 days itineraries starting at $144 to $27,195. You’ll find options that suit your travel style. Whether you’re passionate about Wildlife Viewing, Snorkeling, Archaeological Site Visits, Rainforest Exploration, and Village Visits or eager to explore Panama’s rich culture and natural beauty, our Panama tours 2027 deliver unforgettable moments. Each itinerary blends awe-inspiring exploration with a commitment to sustainability to ensure your adventure supports the preservation of our planet.

Adventure Life’s dedication to personalized travel promises your Panama tour 2027 is seamless from start to finish. From arranging transportation to selecting accommodations tailored to your preferences, we’ll take care of every detail. Our expert recommendations and insider tips make your journey even more enriching.

Contact our specialists today to start planning your Panama tour 2027. Whether you’re a solo traveler, a couple, or part of a group, Adventure Life will create a transformative experience you’ll treasure forever.
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Paradise Tropical Island - Bocas del Toro archipelago - Island Colon
from $2,409
EXPLORE

Panama's Parks and Beaches

9 Day Itinerary
  • Visit ruins of Old Panama
  • Explore the Gailard Cut
  • Pass the Bridge of the Americas
  • Explore mountains and rural life
Starts / Ends
Panama City / Panama City
Activities
Wilderness Lodge Exploration
Activity Level
Relaxed
Choose a 9-day Panama National Parks and Beaches tour, and discover Old Panama ruins, iconic Canal views, lush waterfalls, and thrilling zip line adventures. Experience history, nature, and excitement in one unforgettable journey.
Tour Details
0
Canopy Tree Trek, Scenery with Forest and Waterfall. Boquete, Panama
from $2,772
EXPLORE

Panama Adventure

8 Day Itinerary
  • Hike through tropical forest
  • Take a coffee tour in Boquete
  • Explore the Golf of Chiriqui
  • Snorkel, kayak or hike
Starts / Ends
Panama City / Crowne Plaza Panama Airport
Activity Level
Easy Active
Discover unique wildlife in the vibrant jungles of western Panama as well as charming Caribbean towns through this comprehensive Panama tour. Explore the country through rainforest hikes, urban explorations, and snorkeling outings. Enjoy a remarkable and truly fresh cup of locally grown coffee at the end of the day!
Tour Details
0
Wild Collared Aracari Toucan in Panama's Gamboa Jungle
from $1,920
EXPLORE

Encounter Panama

7 Day Itinerary
  • Explore El Valle's forested trails
  • Transit through the Panama Canal
  • Enjoy the Gamboa Rainforest Resort
  • Visit the Embera community
Activity Level
Relaxed
Begin your Panama journey at the manmade marvel, the Panama Canal, and continue your travels into the region's tropical forests, visiting an indigenous community in Chagres National Park and exploring the ecology of Barro Colorado Island. This is a great introductory tour of Panama!
Tour Details
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A local fisherman pulls his boat ashore at sunset in Costa Rica
from $2,829
EXPLORE

Caribbean Adventure - Bocas Town

8 Day Itinerary
  • Raft down the Pacuare River
  • Choose your days at Selva Bananito
  • Snorkel the marine-rich coral reef
  • Tour Panama's vibrant capital city
Activities
Urban Exploration, Horseback Riding
Activity Level
Easy Active
This 8-day land-based tour highlights the best of Costa Rica and Panama! Whitewater excitement and rainforest exploration in Costa Rica couple with relaxation amidst the turquoise waters of Panama for a perfectly paced vacation. Climb into the rainforest canopy, bask in the sunshine of Bocas del Toro, and fall into the rhythm of the Caribbean!
Tour Details
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Tranquilo Bay indeed...
from $3,788
EXPLORE

Caribbean Adventure

Tranquilo Bay - 9 Day Itinerary
  • Raft down the Pacuare River
  • Hike into the jungle for a swim
  • Marvel at the Panama Canal
  • Snorkel, kayak, hike, or relax
Activities
Whitewater Rafting
Activity Level
Easy Active
Experience the Caribbean from Costa Rica to Panama on this 9-day land-based adventure tour. Whitewater rafting and rainforest exploration along Costa Rica's Pacuare River combine with relaxation amidst the turquoise waters of Panama. Climb into the rainforest canopy, bask in the sunshine of Bocas del Toro, and snorkel & dive among the Caribbean reefs!
Tour Details
0
from $6,832
EXPLORE

Luxury Panama Escape

9 Day Itinerary
  • Mangrove kayaking in Bocas del Toro
  • Explore optional excursions
  • Tour Panama's vibrant capital city
  • Visit Panama La Vieja
Starts / Ends
Panama City / Panama City
Activity Level
Relaxed
Discover Panama with our 9-day itinerary! Immerse yourself in the allure of Boquete's charming town, indulge in the unique experiences at Nayara Bocas del Toro, unwind on pristine beaches, and culminate your journey with a captivating Panama City tou
Tour Details
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Guests explore by zodiac cruise in Portobelo, Panama
from $6,150
EXPLORE

The Panama Canal, Pearl Islands and Darien Jungle

Southbound - 8 Day Itinerary aboard National Geographic Quest
  • Transit the Panama Canal
  • Explore Darien Jungle
  • Visit Portobelo Forts
  • Snorkel Pearl Islands
Starts / Ends
Panama City / Panama City
Activity Level
Variable
Embark on an 8-day Panama Canal, Pearl Islands and Darien Jungle cruise aboard National Geographic. Quest in Colon and explore Panama’s Pacific coast. Cruise Gatun Lake, hike Barro Colorado Island trails, and visit the Pearl Islands. Discover Darien National Park’s rainforest and culture, explore Punta Patiño Reserve, and return to Panama City.
Cruise Details
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Blue water and lush rain forest in Panama
from $6,150
EXPLORE

The Panama Canal, Pearl Islands and Darien Jungle

Balboa to Colon - 8 Day Itinerary aboard National Geographic Quest
  • Panama Canal transit
  • Chagres River cruise
  • Kayak and snorkel at Isla del Rey
  • Explore Playa Muerto
Starts / Ends
Panama City / Panama City
Activities
Snorkeling, Wildlife Viewing, Rainforest Exploration, Village Visits, Hiking, Archaeological Site Visits, Kayaking, Stand Up Paddle Boarding
Activity Level
Variable
Explore Panama on an 8-day cruise aboard National Geographic Quest. Transit the Panama Canal, anchor in Gatun Lake, and discover Darien National Park and the Pearl Islands. Kayak, hike rainforests, snorkel reefs, and meet Embera communities in remote villages and protected reserves.
Cruise Details
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Panama Canal
from $5,772
EXPLORE

Costa Rica and the Panama Canal

Eastbound - 8 Day Itinerary aboard National Geographic Quest
  • Observe animals in their habitat
  • Kayak through magical mangroves
  • Transit the historical Panama Canal
  • Explore Gulf of Panama beaches
Activity Level
Variable
Discover Costa Rica & Panama on this 8-day cruise aboard the National Geographic Quest. Venture into remote wilderness and hike among monkeys, sloths, and tropical birds, explore idyllic islands, snorkel over a vibrant coral reef, and take an expedition landing craft cruise through mangroves.
Cruise Details
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Ruins at the Fortress of Santiago
from $1,142
EXPLORE

Portobelo Extension

4 Day Itinerary
  • Snorkel in the bay of Portobelo
  • Visit Aguas Clara Visitor Center
  • Explore Gatun Lake busy waterway
  • Visit UNESCO Portobelo Forts
Starts / Ends
Panama City / Panama City
Activity Level
Easy Active
Discover Panama's allure with a day exploring Aguas Clara, San Lorenzo Fort, and Portobelo's historic port. Snorkel along picturesque bays and witness colonial charm, designated a UNESCO Patrimony for Humanity.
Tour Details
0
Clear waters of the Caribbean sea
from $11,050
EXPLORE

Panama and Costa Rica by Sea - with Smithsonian Journeys

Puntarenas to Colon - 8 Day Itinerary aboard Le Laperouse
  • Explore Darien National Park
  • Embera village visit
  • See Miraflores Locks view
  • Experience Guna community encounter
Starts / Ends
Puntarenas / Colon
Activity Level
Variable
Set sail on an 8-day cruise from Puntarenas to Colon aboard Le Laperouse. Explore Quepos, Darien National Park, Flamenco Island, the San Blas Islands, and complete the full Panama Canal crossing with cultural encounters and wildlife viewing.
Cruise Details
0
Explore beautiful Costa Rica
from $6,801
EXPLORE

Exploring Arenal Volcano, Pearl Islands and the Panama Canal

San Jose to Panama - 9 Day Itinerary aboard National Geographic Quest
  • Arenal Volcano exploration
  • Relax in Ecotermales hot springs
  • Pearl Islands snorkeling
  • Navigate the Panama Canal
Starts / Ends
San Jose / Panama City
Activities
Land & Sea Exploration
Activity Level
Variable
Arrive in San Jose, transfer to La Fortuna and start the 9-day land and sea adventure. Explore Arenal Volcano and rainforest trails. Fly to Panama City and embark National Geographic Quest. Kayak, hike, and cruise the Panama Canal, Gatun Lake, and Pearl Islands while snorkeling, exploring fortresses, and discovering tropical wildlife.
Cruise Details
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Costa Rica Toucan Bird
from $2,010
EXPLORE

Costa Rica to Panama

Puerto Caldera - Balboa - 8 Day Itinerary aboard Star Clipper
  • Explore Puerto Caldera’s coast
  • Relax on Isla Tortuga’s beaches
  • Experience Golfito’s rich history
  • Snorkel in Golfo de Chiriqui’s
Starts / Ends
Puerto Caldera / Balboa
Activities
Ziplining
Activity Level
Variable
Set sail on an 8-day cruise aboard the Star Clipper, starting in Puerto Caldera, Costa Rica. Explore stunning beaches, vibrant marine parks, and rich history before concluding your adventure in Balboa, Panama.
Cruise Details
0
Panama Canal
from $14,495
EBD
EXPLORE

Costa Rica and The Panama Canal

San Jose - Panama - 12 Day Itinerary aboard Sylvia Earle
  • Cross Panama Canal
  • Explore biodiverse rainforests
  • Visit Coiba National Park
  • Enjoy Manuel Antonio National Park
Starts / Ends
San Jose / Panama City
Activity Level
Variable
Embark on a 12-day cruise aboard the Sylvia Earle to explore Central America's rich ecosystems, from Costa Rica's diverse wildlife to Panama's vibrant coral reefs. Experience a memorable daylight transit through the historic Panama Canal, witnessing this engineering marvel firsthand.
Cruise Details
0
Balboa
from $3,150
EXPLORE

Panama to Aruba

12 Day Itinerary aboard Star Clipper
  • Transit the Panama Canal locks
  • Walk colonial Balboa streets
  • Explore forts in Portobelo
  • Visit San Blas and Guna villages
  • See Cartagena and Santa Marta
Starts / Ends
Balboa / Oranjestad
Activities
Small Ship Sailing, Local Market Visits
Activity Level
Variable
Sail the Panama Canal on a 10-day Star Clippers cruise through Central America. Begin in Balboa, then transit the Panama Canal and see the locks in action. Explore Spanish forts in Portobelo, meet the Guna people in the San Blas Islands, and discover Colombia’s coastal cities of Cartagena and Santa Marta. Enjoy scenic days under sail.
Cruise Details
0
Explore beautiful Costa Rica
from $2,010
SS 25%
EXPLORE

Costa Rica & Panama

Puerto Caldera Roundtrip - 8 Day Itinerary aboard Star Clipper
  • Discover Quepos's authentic charm
  • Experience Golfito's allure
  • Swim Bahia Potrero's calm waters
  • Marvel at Arenal's majestic volcano
Starts / Ends
Puerto Caldera / Puerto Caldera
Activity Level
Variable
Set sail on an 8-day cruise aboard the Star Clipper through Costa Rica and Panama, exploring lush rainforests, pristine beaches, and vibrant marine life. Highlights include Manuel Antonio, Coiba Island, and Isla Tortuga’s turquoise waters.
Cruise Details
0
Look for unique birds and other wildlife in the rain forest!
from $12,965
EBD 30%
EXPLORE

Natural Wonders, Engineering Marvels

Puntarenas - Colon - 13 Day Itinerary aboard Sea Cloud Spirit
  • Explore Nicoya Peninsula beaches
  • Visit Pearl Islands Discover Pea
  • Discover Marina Flamingo
  • Relax at Playa Panama
  • Sail through the Panama Canal
Starts / Ends
Puntarenas / Colon
Activities
Fishing
Activity Level
Variable
Experience the essence of “Pura Vida” on a 13-day Panama cruise from Puntarenas to Colon. Visit Punta Leona, Marina Flamingo, Playa Panama, Quepos, Puerto Jimenez, the Pearl Islands, and the San Blas Archipelago, exploring rainforests, beaches, & marinas while encountering diverse wildlife and witnessing the engineering marvel of the Panama Canal.
Cruise Details
0
Transitioning the Panama Canal
from $348
EXPLORE

Panama Canal Full Transit

1 Day Itinerary
  • See the Panama City skyline
  • Learn the history of the canal
Activity Level
Relaxed
This Panama City one-day tour takes you on the incredible journey from the Atlantic Ocean all the way to the Pacific Ocean, traversing two impressive locks via the manmade wonder that is the Panama Canal.
Tour Details
0
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