Browse the top picks for hotels, lodges, resorts, and accommodation in Panama for 2024-2025. Adventure Life's Panama travel experts have hand picked each of the below hotels because they have unique local flavor, provide excellent service, and serve as an excellent base as you explore Panama. Still can't decide on where the best place to stay in Panama is? No worries, contact one of our Panama travel experts and they'll help match you with the perfect lodging and the perfect trip to Panama.