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Top Panama Tours & Cruises in 2028

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Discover the best the world has to offer with Adventure Life’s expert-curated Panama tours 2028. From Panama City, Panama Canal, Colon, Bocas del Toro, and Portobelo to hidden gems off the beaten path, our 19 top-rated itineraries take you deep into Panama’s breathtaking landscapes. Guided by bilingual experts, these immersive experiences cater to adventurers seeking unique journeys in small groups or customizable private tours.

Choose from a variety of 5 to 9 days itineraries starting at $144 to $10,357. You’ll find options that suit your travel style. Whether you’re passionate about Wildlife Viewing, Snorkeling, Archaeological Site Visits, Hiking, and Rainforest Exploration or eager to explore Panama’s rich culture and natural beauty, our Panama tours 2028 deliver unforgettable moments. Each itinerary blends awe-inspiring exploration with a commitment to sustainability to ensure your adventure supports the preservation of our planet.

Adventure Life’s dedication to personalized travel promises your Panama tour 2028 is seamless from start to finish. From arranging transportation to selecting accommodations tailored to your preferences, we’ll take care of every detail. Our expert recommendations and insider tips make your journey even more enriching.

Contact our specialists today to start planning your Panama tour 2028. Whether you’re a solo traveler, a couple, or part of a group, Adventure Life will create a transformative experience you’ll treasure forever.
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Wild Collared Aracari Toucan in Panama's Gamboa Jungle
from $2,011
EXPLORE

Encounter Panama

7 Day Itinerary
  • Explore El Valle's forested trails
  • Transit through the Panama Canal
  • Enjoy the Gamboa Rainforest Resort
  • Visit the Embera community
Activity Level
Relaxed
Begin your Panama journey at the manmade marvel, the Panama Canal, and continue your travels into the region's tropical forests, visiting an indigenous community in Chagres National Park and exploring the ecology of Barro Colorado Island. This is a great introductory tour of Panama!
Tour Details
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A local fisherman pulls his boat ashore at sunset in Costa Rica
from $2,829
EXPLORE

Caribbean Adventure - Bocas Town

8 Day Itinerary
  • Raft down the Pacuare River
  • Choose your days at Selva Bananito
  • Snorkel the marine-rich coral reef
  • Tour Panama's vibrant capital city
Activities
Horseback Riding, Wilderness Lodge Exploration
Activity Level
Easy Active
This 8-day land-based tour highlights the best of Costa Rica and Panama! Whitewater excitement and rainforest exploration in Costa Rica couple with relaxation amidst the turquoise waters of Panama for a perfectly paced vacation. Climb into the rainforest canopy, bask in the sunshine of Bocas del Toro, and fall into the rhythm of the Caribbean!
Tour Details
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Tranquilo Bay indeed...
from $3,788
EXPLORE

Caribbean Adventure

Tranquilo Bay - 9 Day Itinerary
  • Raft down the Pacuare River
  • Hike into the jungle for a swim
  • Marvel at the Panama Canal
  • Snorkel, kayak, hike, or relax
Activities
Whitewater Rafting
Activity Level
Easy Active
Experience the Caribbean from Costa Rica to Panama on this 9-day land-based adventure tour. Whitewater rafting and rainforest exploration along Costa Rica's Pacuare River combine with relaxation amidst the turquoise waters of Panama. Climb into the rainforest canopy, bask in the sunshine of Bocas del Toro, and snorkel & dive among the Caribbean reefs!
Tour Details
0
from $7,157
EXPLORE

Luxury Panama Escape

9 Day Itinerary
  • Mangrove kayaking in Bocas del Toro
  • Explore optional excursions
  • Tour Panama's vibrant capital city
  • Visit Panama La Vieja
Starts / Ends
Panama City / Panama City
Activity Level
Relaxed
Discover Panama with our 9-day itinerary! Immerse yourself in the allure of Boquete's charming town, indulge in the unique experiences at Nayara Bocas del Toro, unwind on pristine beaches, and culminate your journey with a captivating Panama City tou
Tour Details
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Guests explore by zodiac cruise in Portobelo, Panama
from $6,150
EXPLORE

The Panama Canal, Pearl Islands and Darien Jungle

Southbound - 8 Day Itinerary aboard National Geographic Quest
  • Transit the Panama Canal
  • Explore Darien Jungle
  • Visit Portobelo Forts
  • Snorkel Pearl Islands
Starts / Ends
Panama City / Panama City
Activity Level
Variable
Embark on an 8-day Panama Canal, Pearl Islands and Darien Jungle cruise aboard National Geographic. Quest in Colon and explore Panama’s Pacific coast. Cruise Gatun Lake, hike Barro Colorado Island trails, and visit the Pearl Islands. Discover Darien National Park’s rainforest and culture, explore Punta Patiño Reserve, and return to Panama City.
Cruise Details
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Blue water and lush rain forest in Panama
from $6,150
EXPLORE

The Panama Canal, Pearl Islands and Darien Jungle

Balboa to Colon - 8 Day Itinerary aboard National Geographic Quest
  • Panama Canal transit
  • Chagres River cruise
  • Kayak and snorkel at Isla del Rey
  • Explore Playa Muerto
Starts / Ends
Panama City / Panama City
Activities
Snorkeling, Wildlife Viewing, Rainforest Exploration, Village Visits, Hiking, Archaeological Site Visits, Kayaking, Stand Up Paddle Boarding
Activity Level
Variable
Explore Panama on an 8-day cruise aboard National Geographic Quest. Transit the Panama Canal, anchor in Gatun Lake, and discover Darien National Park and the Pearl Islands. Kayak, hike rainforests, snorkel reefs, and meet Embera communities in remote villages and protected reserves.
Cruise Details
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Panama Canal
from $6,790
EXPLORE

Costa Rica and the Panama Canal

Eastbound - 8 Day Itinerary aboard National Geographic Quest
  • Observe animals in their habitat
  • Kayak through magical mangroves
  • Transit the historical Panama Canal
  • Explore Gulf of Panama beaches
Activity Level
Variable
Discover Costa Rica & Panama on this 8-day cruise aboard the National Geographic Quest. Venture into remote wilderness and hike among monkeys, sloths, and tropical birds, explore idyllic islands, snorkel over a vibrant coral reef, and take an expedition landing craft cruise through mangroves.
Cruise Details
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Ruins at the Fortress of Santiago
from $1,196
EXPLORE

Portobelo Extension

4 Day Itinerary
  • Snorkel in the bay of Portobelo
  • Visit Aguas Clara Visitor Center
  • Explore Gatun Lake busy waterway
  • Visit UNESCO Portobelo Forts
Starts / Ends
Panama City / Panama City
Activity Level
Easy Active
Discover Panama's allure with a day exploring Aguas Clara, San Lorenzo Fort, and Portobelo's historic port. Snorkel along picturesque bays and witness colonial charm, designated a UNESCO Patrimony for Humanity.
Tour Details
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Explore beautiful Costa Rica
from $6,853
EXPLORE

Exploring Arenal Volcano, Pearl Islands and the Panama Canal

San Jose to Panama - 9 Day Itinerary aboard National Geographic Quest
  • Arenal Volcano exploration
  • Relax in Ecotermales hot springs
  • Pearl Islands snorkeling
  • Navigate the Panama Canal
Starts / Ends
San Jose / Panama City
Activities
Land & Sea Exploration
Activity Level
Variable
Arrive in San Jose, transfer to La Fortuna and start the 9-day land and sea adventure. Explore Arenal Volcano and rainforest trails. Fly to Panama City and embark National Geographic Quest. Kayak, hike, and cruise the Panama Canal, Gatun Lake, and Pearl Islands while snorkeling, exploring fortresses, and discovering tropical wildlife.
Cruise Details
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Transitioning the Panama Canal
from $365
EXPLORE

Panama Canal Full Transit

1 Day Itinerary
  • See the Panama City skyline
  • Learn the history of the canal
Activity Level
Relaxed
This Panama City one-day tour takes you on the incredible journey from the Atlantic Ocean all the way to the Pacific Ocean, traversing two impressive locks via the manmade wonder that is the Panama Canal.
Tour Details
0
View of the Miraflores Locks
from $299
EXPLORE

Panama Canal Partial Transit

½ Day Itinerary
  • Transit through Miraflores Locks
  • Learn the history of the canal
Activity Level
Relaxed
Climb aboard and experience the "Eighth Wonder of the World" first hand as you transit through the Miraflores Locks to the Pacific Ocean.
Tour Details
0
Cathedral of Casco Viejo
from $343
EXPLORE

Explore Panama City

½ Day Itinerary
  • Tour the ruins of Panama La Vieja
  • Watch a transit of the Panama Canal
Activities
Urban Exploration
Activity Level
Relaxed
Tour Panama City with a local guide, well versed in the history of the area. See a transit of the Panama canal and tour Casco Antiguo where the pirate Henry Morgan waged his attack in 1671.
Tour Details
0
Capuchin monkey
from $283
EXPLORE

Barro Colorado Island Tour

1 Day Itinerary
Activity Level
Easy Active
Visit Barro Colorado Island while in the Panama City with a boat ride in Gatún Lake. Enjoy a day exploring the Smithsonian Tropical Research Institute and learn about the current studies underway. This man-made island was created when the canal was flooded preserving a breathtaking array of diverse wildlife and jungle on the tiny island.
Tour Details
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An old fort of Panama
from $374
EXPLORE

San Lorenzo and Agua Claras Locks

1 Day Itinerary
  • Visit historic San Lorenzo Fort
  • Visit the Gatun Locks
  • Witness Panama Canal expansion
Activity Level
Relaxed
Visit Aguas Clara Visitor Center for stunning Gatun Lake views and marvel at the historic San Lorenzo Fort. Explore scenic landscapes, rich wildlife, and Panama Canal expansion highlights in one action-packed day.
Tour Details
0
El Valle de Anton Valley
from $361
EXPLORE

El Valle de Anton

1 Day Itinerary
Activities
Ziplining, Local Market Visits
Activity Level
Moderate
Drive from Panama City to El Valle: hike, zipline above El Macho Falls, explore the market, enjoy lunch & thermal pools.
Tour Details
0
from $293
EXPLORE

Embera Drua Community Visit

1 Day Itinerary
  • Discover traditional music & dance
  • Try traditional body painting
Activity Level
Relaxed
Experience native Panamanian culture deep in the Chagres rainforest. Visit with the people of the Embera Dura community and hike through the jungle with your guide.
Tour Details
0
Zapatilla Cay, Panama
from $172
EXPLORE

Dolphin Bay and Zapatilla Island Snorkeling

½ Day Itinerary
Activity Level
Relaxed
Tour Details
0
Traditional folklore dance of Panama
from $147
EXPLORE

Las Tinajas Folklore Dinner Show

½ Day Itinerary
  • Sample Panamanian fare
  • Enjoy a telling of Panama folklore
Activity Level
Relaxed
Enjoy dinner and a show with this evening event full of the sights and smells of Panamanian tradition.
Tour Details
0
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