Top South America Tours & Cruises in 2028

This 13-day tour of Chile takes you from Northern Chile's Atacama Desert, to Santiago, the Lake District, then Torres del Paine. Along the way, enjoying hiking, biking, wine tasting, rafting, and other activities as you experience both the metropolitan and natural sides of Chile.

This 8-day multisport adventure to the Galapagos Islands is packed with thrilling and unique experiences. Begin your action-packed trip with a trek on San Cristobal Island, and then continue with kayaking, snorkeling, and biking around the Galapagos, where wildlife awaits at every turn, trailside, and shoreline!

This 13-day Patagonian adventure covers the region’s highlights. Explore Tierra del Fuego National Park, cruise the fjords on an Australis voyage, discover Torres del Paine, experience a traditional Patagonian dinner and end in El Calafate. Visit Magdalena Island’s penguins, hike iconic trails, and trek the impressive Perito Moreno Glacier.

Fernando de Noronha is a Brazil tour itinerary offered through Adventure Life. Review the day-by-day highlights and what's included, or contact a trip planner to customize the itinerary to your travel dates and interests.

Join this 8-day tour that takes you to Lima, Cusco, the Sacred Valley, and the citadel of Machu Picchu. Explore the culinary delights of Peru in Barranco, where you can taste traditional dishes like lomo saltado and causa. This is a relaxed, cultural-focused trip with an emphasis on the flavors and gastronomy of Peru.

This two-week trek explores the ancient and revered pathway known as the Inca Trail through the Sacred Valley of the Inca. Spend 4 days hiking the 26-mile Inca Trail, culminating in Machu Picchu at the Sun Gate. This tour also spends time before the trek acclimating and exploring Lake Titicaca and Cusco.

Bike down the slopes of Pichincha Volcano, hike through dense, biodiverse cloud forest, zip-line over the forest canopy, hike, and ride horses through the high Andes near the active 19,347-foot high Cotopaxi Volcano on this exciting 9-day adventure tour of Ecuador.

Explora Torres del Paine is in the middle of the Torres del Paine National Park. It offers beautiful views of the Lake Pehoe and 49 rooms. Explora also has its own spa, ranch, and stables for your enjoyment and you can choose from a variety of excursions to create your optimal itinerary.

This 11-day trip along the legendary Salkantay Trail to Machu Picchu hosts you in luxury lodges as you visit such iconic archaelogical sites and towns like Colpa Lodge, Lucma Lodge, Wayra Lodge, Aguas Calientes (Machu Picchu Pueblo), Cusco, and Lima, filled with adventure and trekking to take you through these breathtaking landscapes.

Combine a Galápagos expedition aboard the National Geographic Endeavour II with a land-based exploration of Machu Picchu and Peru’s rich Inca heritage on this unforgettable 16-day adventure. Make the most of your travel time as your expedition team makes the transition effortless for you.

Witness the greatest spectacle of evolution and dynamic volcanic terrains on this 8-day West Galapagos expedition from Santa Cruz Island to Baltra Island aboard Aqua Mare. Tour Fausto Llerena Breeding Centre, Punta Cormorant, Punta Moreno, Punta Espinoza, Puerto Egas, Rábida, North Seymour, and Mosquera.

Explore Central East & Southern Islands on this 8-day cruise aboard Hermes Ultra Luxury Cruise. Visit Baltra and meet giant tortoises. Enjoy geological wonders and encounter diverse wildlife on Rábida, Bartolomé, South Plaza, and Santa Fe. End at Fausto Llerena Breeding Center to see Galápagos tortoises and support conservation efforts.