Have questions? We're here.
Barn in Minnesota

Midwestern Majesty

Example 8 Day Cruise aboard MS Louisiane
Talk with an expert
Build your ideal United States trip. Call 1.406.541.2677
Start Planning My Trip
As fall arrives, the majestic reds, oranges and yellows of the leaves begin to ripple across the rolling hills of the Midwest. Experience autumn among the trees in magical Great River Bluffs State Park in Winona. Be sure to ask the locals for the perfect wine and cheese pairing in Prairie du Chien. Visit Mark Twain's modest boyhood home in Hannibal, admire the striking public art along the river in Dubuque, and take in the panoramic view from the top of the Davenport Skybridge.
Barn in Minnesota
Highlights
  • Visit Mark Twain's boyhood home in Hannibal, Missouri
  • Enjoy the public art scene in Dubuque, Iowa
  • Explore the Cathedral of St. Paul in St. Paul, Minnesota
  • Admire Sugar Loaf in Minnesota's bluff country
Activities
Activity Level: Relaxed
Involves minimal physical effort and is typically associated with leisurely activities. Activities are low-intensity or last less than a few hours each day.
0

Full Itinerary

Expand All

Day 1: St. Paul, Minnesota

  • 1 Dinner
Arrive in St. Paul and check in to your deluxe hotel, which is adjacent to the city’s attractions. Admire the Cathedral of St. Paul, a beaux-arts wonder that replicates St. Peter's in Rome, and soak in the arts at the city's world-class museums, including the Walker Art Center. Detour to Minnehaha Falls, best known for Longfellow's Song of Hiawatha.

Day 2: St. Paul, Minnesota | Embarkation

Your fare includes breakfast this morning at your hotel as well as a transfer to the Louisiane and all porterage. Settle into your stateroom or suite, head to The Veranda for a light snack, and then bid St. Paul farewell as the Louisiane departs and you immerse yourself in the joys of life on the river. Bon voyage!

Day 3: Winona, Minnesota

Be awed by lofty Sugar Loaf, one of the most recognizable topographical landmarks along Minnesota's bluff country. Find further inspiration at the Minnesota Marine Art Museum, which features one of the two original versions of Leutze's Washington Crossing the Delaware.

Day 4: Prairie du Chien, Wisconsin

Contemplate 10,000 years of Native American history at this once bustling fur-trading center, now host to five National Historic Landmarks, including the Victorian stunner Villa Louis. Locals insist you stop by Valley Fish and Cheese for their mouthwatering victuals.

Day 5: Dubuque, Iowa

Build up your knowledge of early river commerce much as the lumber barons built countless landmarks at this confluence of three states. Ride the Fenelon Place Elevator Co., a historic funicular that affords an unmatched view from atop the bluffs.

Day 6: Davenport, Iowa

Appreciate the exploding cultural scene at this city founded on the site of the 1832 Black Hawk purchase, host to the yearly festival held in honor of local Bix Biederbecke, the "giant of cornetists", and the excellent Figge Art Museum.

Day 7: Hannibal, Missouri

Pay tribute to Samuel Clemens, better known as Mark Twain, at his Boyhood Home and Museum in this welcoming town. Reenact Tom and Huck's exploits if you're feeling mischievous, as Hannibal provided the setting for their quintessentially American adventures.

Day 8: St. Louis, Missouri | Disembarkation

  • 1 Breakfast
Bid adieu to the Louisiane and explore St. Louis. Wonder at the St. Louis Arch, an unequaled architectural statement that defines this storied town, then continue your architectural tour at the imposing Cathedral of St. Louis. Indulge in a less lofty American pastime at the Anheuser-Busch brewery, an American classic.

Ship/Hotel

MS Louisiane

MS Louisiane French Quarter Lounge
MS Louisiane Veranda
MS Louisiane Currents Spa

Dates & Prices

My Preferred Start Date

 May 2025>
SMTWTFS
27282930123
45678910
11121314151617
18192021222324
25262728293031
Available departures
Selected departure
This itinerary is no longer available. For other trip ideas, please visit United States Small Ship Cruises, River Cruises & Tours.

Notes

All fares, including land and hotel, are capacity controlled, subject to change at anytime without notice, and do not guarantee availability.

A Single Supplement of 50% is available only for the Deluxe, French Balcony, Promenade, and Veranda Staterooms.
Included
  • 7 Breakfasts, 6 Lunches, 7 Dinners
  • 7 Nights Accommodations
  • Accommodations as listed
  • Ground transportation as listed
  • Activities as listed
  • Meals as listed
  • Access to a 24-7 Emergency line while traveling
Excluded
  • Gratuities
  • Travel Insurance
  • Personal Expenses
  • Flight costs (please request a quote)
  • Additional excursions during free time
  • Fuel and transportation surcharges (when applicable)

Map

Inquire

* By providing your phone number, you consent to receive direct phone calls or SMS messages from our Trip Planners to get the process started. We do not share your information with third-parties.
Change & customize to make it yours.
Travel Agents

We Love to Talk Travel

Call 1.800.344.6118
or
Chat Now
Kate was great to work with in the planning stage. She was prompt, helpful, and efficient. Our tour guide, Edwin, was knowledgeable and passionate. We were very happy to have traveled with Adventure Life, it made the trip easy and a true pleasure. We could concentrate on enjoying the experience rather than the details of travel.
Lisa Bridge

United States Travel Guide

Top United States Travel Destinations

United States Trips by Departure Date

Top Experiences in United States

United States Trips by Duration

United States Trips by Activity

More Reasons

Why Travel With Adventure Life

All News

Recognized By