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12-Day United States Cruises

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United States
Kayaking
Columbia River
Sunrise over Crown Point at Columbia River
Cumberland River
Explore historic Nashville, Tennessee
Florida
Fort Lauderdale strip aerial view
Hawaii
Halawa Bay on Molokai
Illinois River
Aerial views of Chicago
New England
Springtime in Boston
Ohio River
Pacific Northwest
Bridge over Columbia River to Mount Hood
Tennessee River
unsplash
Chattanooga Tennessee
Washington
Explore the landscape of the Pacific northwest
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Discover the wonders of the United States on Adventure Life's 12-day tours this 2025. From the vibrant city of New Orleans to the historic landmarks of Memphis, immerse yourself in the rich culture and heritage of the Mississippi River. Experience the music scene in the Mississippi Delta, savor the flavors of Cajun cuisine, delve into Civil War history, and admire the stunning architecture of Natchez's historic homes. Whether you choose to cruise the river, explore urban gems, or visit charming villages, each day offers a new adventure. Don't miss the chance to explore the Heart of the Delta and beyond on a journey filled with archaeological site visits, river cruises, and urban exploration. To embark on a seamless trip filled with history, music, and culinary delights, contact one of our Trip Planners.
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    • United States
Visit amazing wilderness camp in Alaska
from $3,790
EXPLORE

Alaska Denali Camping Expedition

Alaska Small Group Tour - 12 Day Itinerary
  • Spot wildlife in Anchorage
  • Camp next to Maclaren Glacier
  • Trek through Denali National Park
  • Enjoy evenings around the campfire
  • Explore St. Elias National Park
Starts / Ends
Anchorage / Anchorage
Activities
Hiking, Camping, Kayaking
Activity Level
Variable
Join 12-day small group expedition through Alaska's breathtaking wilderness. Encounter diverse wildlife, explore remote campsites, and immerse yourself in thrilling activities across Denali, Wrangell/St Elias NP, Valdez
Tour Details
0
Edgartown on Martha's Vineyard
from $10,170
Savings
EXPLORE

New England Explorer

Boston Roundtrip - 12 Day Itinerary aboard American Patriot
  • Visit Portland Head Lighthouse
  • Learn about Wabanaki culture
  • Tour Bath's Maritime Museum
  • Discover Martha’s Vineyard Museum
Starts / Ends
Boston / Boston
Activities
Local Market Visits
Activity Level
Variable
Embark on a 12-day coastal cruise of New England aboard American Patriot. Visit Portland, Rockland, Bar Harbor, Boothbay Harbor, Bath, Gloucester, Newport, and Martha’s Vineyard. Enjoy guided tours, seafood feasts, museums, and scenic cruising.
Cruise Details
0
Alaska
from $9,275
Savings
EXPLORE

Alaskan Explorer Cruise

Juneau Roundtrip - 12 Day Itinerary aboard American Constitution
  • Watch for breaching whales
  • Discover Haines’ rich history
  • Visit charming Sitka
  • Travel through Frederick Sound
Starts / Ends
Juneau / Juneau
Activity Level
Variable
Embark on a 12-day Alaskan Explorer cruise aboard the American Constitution, taking in Alaska’s untouched landscapes. The adventure begins and ends in Juneau, with stops in Haines, Glacier Bay, Sitka, Petersburg, Wrangell, and Dawes Glacier.
Cruise Details
0
The MS Endeavour in the Inside Passage
from $9,275
Savings
EXPLORE

Alaskan Explorer Cruise

Juneau Roundtrip - 12 Day Itinerary aboard American Constellation
  • Explore Juneau
  • Experience Inside Passage
  • Discover Glacier Bay National Park
  • Explore Haines
Starts / Ends
Juneau / Juneau
Activity Level
Variable
Embark on a 12-day cruise aboard the American Constellation, departing and returning to Juneau. Explore historical sites, stunning scenery, and lively ports in Southern Alaska and the Inside Passage, including Glacier Bay, Endicott Arm, and Dawes Glacier, cultural excursions, and outdoor adventures.
Cruise Details
0
Visit historic Memphis, Tennessee
from $6,360
Savings
EXPLORE

Mississippi River Gateway Cruise

New Orleans to Louisville - 12 Day Itinerary aboard American Heritage
  • Explore Oak Alley Plantation
  • See Paducah wall murals
  • Explore Sun Studio
  • Visit Elvis Presley’s estate
Starts / Ends
New Orleans / Louisville
Activities
Wildlife Viewing, Village Visits, Archaeological Site Visits, Urban Exploration
Activity Level
Variable
Embark on a 12-day Mississippi River cruise from New Orleans to Louisville aboard American Heritage. Explore iconic sites like Oak Alley, Vicksburg, and Memphis. Enjoy enriching excursions, Civil War history, live music, and Southern cuisine.
Cruise Details
0
Visit historic Memphis, Tennessee
from $7,275
Savings
EXPLORE

Mississippi Explorer

New Orleans - Memphis - 12 Day Itinerary aboard American Symphony
  • Explore Natchez's Grand Homes
  • Visit Oak Alley
  • Delve into Baton Rouge's history
  • Unravel Vicksburg's Civil War
Starts / Ends
New Orleans / Memphis
Activity Level
Variable
Set sail on a 12-day Mississippi river cruise aboard the American Symphony, from New Orleans to Memphis, visiting Southern landmarks like Oak Alley, Houmas House, and Vicksburg National Military Park. Explore Baton Rouge's history, Natchez's antebellum homes, and Cleveland's musical heritage.
Cruise Details
0
Explore the rivers of America
from $7,775
Savings
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Great Smoky Mountains National Park

Knoxville, TN to Nashville, TN - 12 Day Itinerary aboard American Symphony
  • Stroll through downtown Gatlinburg
  • View Quilt Museum Paducah
  • Visit Grand Ole Opry
  • Walk at Shiloh Military Park
Starts / Ends
Chattanooga / Nashville
Activities
Land & Sea Exploration
Activity Level
Variable
Embark on a 12-day Great Smoky Mountains National Park land and cruise adventure aboard American Symphony. Start in Knoxville and travel through the Great Smoky Mountains to Pigeon Forge, Chattanooga, and more. Ride Jeeps, tour Civil War sites, enjoy local food, and attend the Grand Ole Opry.
Cruise Details
0
Visit Portsmouth
from $7,299
Save 50%
EXPLORE

New England and Canada

Portland - Toronto - 12 Day Itinerary aboard Victory I
  • Explore Portland
  • Watch whales in Saguenay Fjords
  • Walk Old Quebec streets
  • Explore Charlottetown history
Starts / Ends
Portland / Toronto
Activities
Whale Watching
Activity Level
Variable
Experience a 12-day cruise from Portland to Toronto aboard Victory I and enjoy coastal views, local cuisine, and relaxing days at sea. This immersive journey blends Canadian culture, maritime history, and scenic waterways for a unique small-ship cruising experience.
Cruise Details
0
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