Cape Girardeau is a small city that welcomes tourists right on the banks of the mighty Mississippi River. While visiting, you will learn about the author Mark Twain, the explorers Lewis & Clark, and also enjoy amazing panoramas on a bike ride along the river. Most of our Cape Girardeau river cruises will start in the city of St. Louis and veer off onto the Ohio River all the way to Louisville. Contact our travel specialists to start planning your ideal river cruise today!
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