Our Panama Canal Trips & Vacation Packages

from $6,150

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The Panama Canal, Pearl Islands and Darien Jungle

Southbound - 8 Day Itinerary aboard National Geographic Quest

• Transit the Panama Canal
• Explore Darien Jungle
• Visit Portobelo Forts
• Snorkel Pearl Islands

Starts / Ends

Panama City / Panama City

Activity Level

Variable

Embark on an 8-day Panama Canal, Pearl Islands and Darien Jungle cruise aboard National Geographic. Quest in Colon and explore Panama’s Pacific coast. Cruise Gatun Lake, hike Barro Colorado Island trails, and visit the Pearl Islands. Discover Darien National Park’s rainforest and culture, explore Punta Patiño Reserve, and return to Panama City.

Cruise Details

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from $6,150

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The Panama Canal, Pearl Islands and Darien Jungle

Balboa to Colon - 8 Day Itinerary aboard National Geographic Quest

• Panama Canal transit
• Chagres River cruise
• Kayak and snorkel at Isla del Rey
• Explore Playa Muerto

Starts / Ends

Panama City / Panama City

Activities

Village Visits, Rainforest Exploration, Wildlife Viewing, Hiking, Snorkeling, Archaeological Site Visits, Kayaking, Stand Up Paddle Boarding

Activity Level

Variable

Explore Panama on an 8-day cruise aboard National Geographic Quest. Transit the Panama Canal, anchor in Gatun Lake, and discover Darien National Park and the Pearl Islands. Kayak, hike rainforests, snorkel reefs, and meet Embera communities in remote villages and protected reserves.

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from $1,829

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Encounter Panama

7 Day Itinerary

• Explore El Valle's forested trails
• Transit through the Panama Canal
• Enjoy the Gamboa Rainforest Resort
• Visit the Embera community

Activity Level

Relaxed

Begin your Panama journey at the manmade marvel, the Panama Canal, and continue your travels into the region's tropical forests, visiting an indigenous community in Chagres National Park and exploring the ecology of Barro Colorado Island. This is a great introductory tour of Panama!

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from $3,788

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Caribbean Adventure

Tranquilo Bay - 9 Day Itinerary

• Raft down the Pacuare River
• Hike into the jungle for a swim
• Marvel at the Panama Canal
• Snorkel, kayak, hike, or relax

Activities

Whitewater Rafting

Activity Level

Easy Active

Experience the Caribbean from Costa Rica to Panama on this 9-day land-based adventure tour. Whitewater rafting and rainforest exploration along Costa Rica's Pacuare River combine with relaxation amidst the turquoise waters of Panama. Climb into the rainforest canopy, bask in the sunshine of Bocas del Toro, and snorkel & dive among the Caribbean reefs!

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from $3,276

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Discover Panama

8 Day Itinerary

• Trek the lowland tropical forest
• Bike, hike, zipline, raft or relax
• See wildlife in natural habitats
• Explore Tranquilo Bay

Activities

Ziplining, Biking

Activity Level

Easy Active

This 8-day hotel-based tour of Panama takes you from metropolitan Panama City, through the lowland tropical forest of Soberania National Park, snorkeling, kayaking, hiking, surfing, birding, and exploring Bocas del Toro & Tranquilo Bay, and finally to the Miraflores locks of the Panama Canal.

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from $11,050

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Panama and Costa Rica by Sea - with Smithsonian Journeys

Puntarenas to Colon - 8 Day Itinerary aboard Le Laperouse

• Explore Darien National Park
• Embera village visit
• See Miraflores Locks view
• Experience Guna community encounter

Starts / Ends

Puntarenas / Colon

Activity Level

Variable

Set sail on an 8-day cruise from Puntarenas to Colon aboard Le Laperouse. Explore Quepos, Darien National Park, Flamenco Island, the San Blas Islands, and complete the full Panama Canal crossing with cultural encounters and wildlife viewing.

Cruise Details

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from $5,772

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Costa Rica and the Panama Canal

Eastbound - 8 Day Itinerary aboard National Geographic Quest

• Observe animals in their habitat
• Kayak through magical mangroves
• Transit the historical Panama Canal
• Explore Gulf of Panama beaches

Activity Level

Variable

Discover Costa Rica & Panama on this 8-day cruise aboard the National Geographic Quest. Venture into remote wilderness and hike among monkeys, sloths, and tropical birds, explore idyllic islands, snorkel over a vibrant coral reef, and take an expedition landing craft cruise through mangroves.

Cruise Details

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from $6,801

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Exploring Arenal Volcano, Pearl Islands and the Panama Canal

San Jose to Panama - 9 Day Itinerary aboard National Geographic Quest

• Arenal Volcano exploration
• Relax in Ecotermales hot springs
• Pearl Islands snorkeling
• Navigate the Panama Canal

Starts / Ends

San Jose / Panama City

Activities

Land & Sea Exploration

Activity Level

Variable

Arrive in San Jose, transfer to La Fortuna and start the 9-day land and sea adventure. Explore Arenal Volcano and rainforest trails. Fly to Panama City and embark National Geographic Quest. Kayak, hike, and cruise the Panama Canal, Gatun Lake, and Pearl Islands while snorkeling, exploring fortresses, and discovering tropical wildlife.

Cruise Details

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from $4,450

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Barbados to Panama

15 Day Itinerary aboard Royal Clipper

• Explore Bridgetown, Barbados
• Enjoy Grenada's unique aromas
• Discover Dutch colonial Curacao
• Transit the historic Panama Canal

Starts / Ends

Bridgetown / Balboa

Activity Level

Variable

Starting at the Caribbean port of Bridgetown, this 15-day cruise aboard the Royal Clipper sails through the turquoise Caribbean waters en route to the Panama Canal, visiting Grenada, Bonaire, Curacao, Aruba, and Colombia along the way. Explore the tropical jungles, snorkel in vibrant reefs, immerse yourself in tribal culture, and marvel at the Panama Canal.

Cruise Details

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from $12,795

EBD

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Costa Rica and The Panama Canal

San Jose - Panama - 12 Day Itinerary aboard Sylvia Earle

• Cross Panama Canal
• Explore biodiverse rainforests
• Visit Coiba National Park
• Enjoy Manuel Antonio National Park

Starts / Ends

San Jose / Panama City

Activity Level

Variable

Embark on a 12-day cruise aboard the Sylvia Earle to explore Central America's rich ecosystems, from Costa Rica's diverse wildlife to Panama's vibrant coral reefs. Experience a memorable daylight transit through the historic Panama Canal, witnessing this engineering marvel firsthand.

Cruise Details

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from $3,150

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Panama to Aruba

12 Day Itinerary aboard Star Clipper

• Transit the Panama Canal locks
• Walk colonial Balboa streets
• Explore forts in Portobelo
• Visit San Blas and Guna villages
• See Cartagena and Santa Marta

Starts / Ends

Balboa / Oranjestad

Activities

Small Ship Sailing, Local Market Visits

Activity Level

Variable

Sail the Panama Canal on a 10-day Star Clippers cruise through Central America. Begin in Balboa, then transit the Panama Canal and see the locks in action. Explore Spanish forts in Portobelo, meet the Guna people in the San Blas Islands, and discover Colombia’s coastal cities of Cartagena and Santa Marta. Enjoy scenic days under sail.

Cruise Details

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from $6,450

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Panama and Colombia: Exploring the Caribbean Coast

Panama to Cartagena - 8 Day Itinerary aboard National Geographic Quest

• Transit the Panama Canal
• Meet Indigenous people of Guna Yala
• Look for unique tropical wildlife
• See colonial architecture

Starts / Ends

Panama City / Cartagena

Activity Level

Variable

Discover an astonishing trove of natural and cultural treasures as you navigate the Caribbean coasts of Panama and Colombia on this 8-day cruise aboard the National Geographic Quest. Sail from Panama City to Cartagena, with stops in Portobelo, Guna Yala, Archipelago, and more.

Cruise Details

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from $4,450

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Panama to Antigua

15 Day Itinerary aboard Royal Clipper

• Explore Balboa’s colonial charm
• Transit Panama’s iconic canal
• Discover San Blas culture
• Enjoy Aruba’s clear waters

Starts / Ends

Balboa / St. John's

Activity Level

Variable

Set sail on a 15-day Royal Clipper cruise from Balboa, Panama, featuring a full Panama Canal transit and visits to the San Blas Islands, Cartagena, and the Caribbean gems of Aruba, Curacao, and Bonaire. Experience lush Grenada and volcanic St. Lucia, and finish your journey in Antigua, all while enjoying elegant sailing and stunning island views.

Cruise Details

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from $4,330

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Barbados to Panama

Bridgetown - Balboa - 15 Day Itinerary aboard Star Clipper

• Explore Bridgetown’s heritage
• Discover St. George’s coastal views
• Admire Kralendijk’s marine life
• Wander Willemstad’s streets

Starts / Ends

Bridgetown / Balboa

Activity Level

Variable

Set sail on a 15-day cruise with Star Clipper from Bridgetown, Barbados, exploring the Caribbean’s rich culture and history, ending in Balboa, Panama. Visit stunning destinations like Tobago Cays, Grenada, and the San Blas Islands, and experience the Panama Canal.

Cruise Details

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from $24,990

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Pristine Islands of the Bahamas & the Panama Canal

Nassau - Panama City - 11 Day Itinerary aboard Scenic Eclipse

• Explore Nassau’s colonial streets
• Visit Staniel Cay’s beaches
• Discover San Salvador’s coral reefs
• Meet Cabo de La Vela’s Wayuu people

Starts / Ends

Nassau / Panama City

Activity Level

Variable

Join an 11-day cruise from Nassau to Panama City on the Scenic Eclipse, exploring the Bahamas' clear waters and vibrant island cultures. Experience highlights like Pig Beach and the Panama Canal, blending leisure with cultural discovery.

Cruise Details

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from $12,965

EBD 30%

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Natural Wonders, Engineering Marvels

Puntarenas - Colon - 13 Day Itinerary aboard Sea Cloud Spirit

• Explore Nicoya Peninsula beaches
• Visit Pearl Islands Discover Pea
• Discover Marina Flamingo
• Relax at Playa Panama
• Sail through the Panama Canal

Starts / Ends

Puntarenas / Colon

Activities

Fishing

Activity Level

Variable

Experience the essence of “Pura Vida” on a 13-day Panama cruise from Puntarenas to Colon. Visit Punta Leona, Marina Flamingo, Playa Panama, Quepos, Puerto Jimenez, the Pearl Islands, and the San Blas Archipelago, exploring rainforests, beaches, & marinas while encountering diverse wildlife and witnessing the engineering marvel of the Panama Canal.

Cruise Details

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from $332

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Panama Canal Full Transit

1 Day Itinerary

• See the Panama City skyline
• Learn the history of the canal

Activity Level

Relaxed

This Panama City one-day tour takes you on the incredible journey from the Atlantic Ocean all the way to the Pacific Ocean, traversing two impressive locks via the manmade wonder that is the Panama Canal.

Tour Details

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from $281

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Panama Canal Partial Transit

½ Day Itinerary

• Transit through Miraflores Locks
• Learn the history of the canal

Activity Level

Relaxed

Climb aboard and experience the "Eighth Wonder of the World" first hand as you transit through the Miraflores Locks to the Pacific Ocean.

Tour Details

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