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Our Panama Canal Trips & Vacation Packages

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Discover the awe-inspiring wonders of the Panama Canal with our 27 unique trips for 2026. Join us on one of these top-rated vacation packages, as curated by the Panama Canal experts at Adventure Life, and explore the engineering marvel that connects the Atlantic and Pacific Oceans. From cultural excursions to wildlife viewing opportunities, each journey offers a chance to witness the rich biodiversity and historical significance of this iconic waterway. Whether you're exploring vibrant local markets, trekking through lush rainforests, or embarking on a river cruise, there are endless adventures awaiting you in Panama. With trips ranging from , there's a perfect itinerary for every type of traveler. Don't miss this opportunity to uncover the beauty and intrigue of the Panama Canal. Contact one of our Panama Canal specialists for help planning your next seamless trip.
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Guests explore by zodiac cruise in Portobelo, Panama
from $6,150
HALF DEP
EXPLORE

The Panama Canal, Pearl Islands and Darien Jungle

Southbound - 8 Day Itinerary aboard National Geographic Quest
  • Transit the Panama Canal
  • Explore Darien Jungle
  • Visit Portobelo Forts
  • Snorkel Pearl Islands
Starts / Ends
Panama City / Panama City
Activity Level
Variable
Embark on an 8-day Panama Canal, Pearl Islands and Darien Jungle cruise aboard National Geographic. Quest in Colon and explore Panama’s Pacific coast. Cruise Gatun Lake, hike Barro Colorado Island trails, and visit the Pearl Islands. Discover Darien National Park’s rainforest and culture, explore Punta Patiño Reserve, and return to Panama City.
Cruise Details
0
Blue water and lush rain forest in Panama
from $6,150
HALF DEP
EXPLORE

The Panama Canal, Pearl Islands and Darien Jungle

Northbound - 8 Day Itinerary aboard National Geographic Quest
  • Panama Canal transit
  • Chagres River cruise
  • Kayak and snorkel at Isla del Rey
  • Explore Playa Muerto
Starts / Ends
Panama City / Panama City
Activities
Stand Up Paddle Boarding
Activity Level
Variable
Explore Panama on an 8-day cruise aboard National Geographic Quest. Transit the Panama Canal, anchor in Gatun Lake, and discover Darien National Park and the Pearl Islands. Kayak, hike rainforests, snorkel reefs, and meet Embera communities in remote villages and protected reserves.
Cruise Details
0
Wild Collared Aracari Toucan in Panama's Gamboa Jungle
from $1,829
EXPLORE

Encounter Panama

7 Day Itinerary
  • Explore El Valle's forested trails
  • Transit through the Panama Canal
  • Enjoy the Gamboa Rainforest Resort
  • Visit the Embera community
Activity Level
Relaxed
Begin your Panama journey at the manmade marvel, the Panama Canal, and continue your travels into the region's tropical forests, visiting an indigenous community in Chagres National Park and exploring the ecology of Barro Colorado Island. This is a great introductory tour of Panama!
Tour Details
0
Tranquilo Bay indeed...
from $3,788
EXPLORE

Caribbean Adventure

Tranquilo Bay - 9 Day Itinerary
  • Raft down the Pacuare River
  • Hike into the jungle for a swim
  • Marvel at the Panama Canal
  • Snorkel, kayak, hike, or relax
Activities
Whitewater Rafting
Activity Level
Easy Active
Experience the Caribbean from Costa Rica to Panama on this 9-day land-based adventure tour. Whitewater rafting and rainforest exploration along Costa Rica's Pacuare River combine with relaxation amidst the turquoise waters of Panama. Climb into the rainforest canopy, bask in the sunshine of Bocas del Toro, and snorkel & dive among the Caribbean reefs!
Tour Details
0
from $3,276
EXPLORE

Discover Panama

8 Day Itinerary
  • Trek the lowland tropical forest
  • Bike, hike, zipline, raft or relax
  • See wildlife in natural habitats
  • Explore Tranquilo Bay
Activities
Ziplining, Biking
Activity Level
Easy Active
This 8-day hotel-based tour of Panama takes you from metropolitan Panama City, through the lowland tropical forest of Soberania National Park, snorkeling, kayaking, hiking, surfing, birding, and exploring Bocas del Toro & Tranquilo Bay, and finally to the Miraflores locks of the Panama Canal.
Tour Details
0
Ruins in Colon, Panama
from $13,300
EXPLORE

Costa Rica & Panama Coastal Expedition Cruise

Liberia Airport to Panama City - 15 Day Itinerary aboard Safari Voyager
  • Explore Santa Rosa Wilderness
  • Visit Embera Cultural Village
  • Cross Panama Canal
  • Discover Guna Yala Islands
Starts / Ends
Liberia / Panama City
Activities
Village Visits, Rainforest Exploration, Wildlife Viewing, Hiking, Snorkeling, Archaeological Site Visits, Kayaking, Whale Watching
Activity Level
Variable
Experience a 15-day expedition cruise from Liberia, Costa Rica, to Panama City, Panama, aboard Safari Voyager. Explore remote national parks, tropical islands, vibrant reefs, and Indigenous communities while kayaking, snorkeling, hiking, and crossing the iconic Panama Canal on an unforgettable small-ship adventure.
Cruise Details
0
Ocean view of the edge of Manuel Antonio National Park, Costa Rica
from $6,450
EXPLORE

The Natural Wonders of Central America – with Smithsonian Journeys

Colon to Puntarenas - 8 Day Itinerary aboard Le Bougainville
  • Visit San Blas Islands
  • Cross Panama Canal locks
  • Discover Balboa waterfront district
  • Reach Puntarenas Pacific coast
Starts / Ends
Colon / Puntarenas
Activities
Local Market Visits
Activity Level
Variable
Explore Panama and Costa Rica on an 8-day voyage aboard Le Bougainville. Visit Colon, Portobelo, the San Blas Islands, Balboa, Quepos, and Puntarenas. Cross the Panama Canal, discover Afro-Caribbean heritage, meet Indigenous communities, relax at sea, and experience rainforest-lined Pacific shores.
Cruise Details
0
Clear waters of the Caribbean sea
from $7,170
EXPLORE

Panama and Costa Rica by Sea - with Smithsonian Journeys

Puntarenas to Colon - 8 Day Itinerary aboard Le Laperouse
  • Explore Darien National Park
  • Embera village visit
  • See Miraflores Locks view
  • Experience Guna community encounter
Starts / Ends
Puntarenas / Colon
Activity Level
Variable
Set sail on an 8-day cruise from Puntarenas to Colon aboard Le Laperouse. Explore Quepos, Darien National Park, Flamenco Island, the San Blas Islands, and complete the full Panama Canal crossing with cultural encounters and wildlife viewing.
Cruise Details
0
Keel-billed Toucan
from $6,230
EXPLORE

Central America Jewels & Panama Canal

Colon to Puntarenas - 8 Day Itinerary aboard Le Laperouse
  • Explore San Blas Islands
  • Discover Historic Portobelo
  • Transit Panama Canal
  • Encounter Costa Rica Wildlife
Starts / Ends
Colon / Puntarenas
Activities
Spa Relaxation
Activity Level
Variable
Explore Panama and Costa Rica on this 8-day voyage from Colón to Puntarenas aboard Le Laperouse. Travel through the Panama Canal, visit the San Blas Islands, Portobelo and Darién National Park, and discover local communities, coastal landscapes and wildlife. The journey also includes time at sea and excursions in Costa Rica’s Osa Peninsula region.
Cruise Details
0
Panama Canal
from $5,772
HALF DEP
EXPLORE

Costa Rica and the Panama Canal

Eastbound - 8 Day Itinerary aboard National Geographic Quest
  • Observe animals in their habitat
  • Kayak through magical mangroves
  • Transit the historical Panama Canal
  • Explore Gulf of Panama beaches
Activity Level
Variable
Discover Costa Rica & Panama on this 8-day cruise aboard the National Geographic Quest. Venture into remote wilderness and hike among monkeys, sloths, and tropical birds, explore idyllic islands, snorkel over a vibrant coral reef, and take an expedition landing craft cruise through mangroves.
Cruise Details
0
Explore beautiful Costa Rica
from $6,801
HALF DEP
EXPLORE

Exploring Arenal Volcano, Pearl Islands and the Panama Canal

San Jose to Panama - 9 Day Itinerary aboard National Geographic Quest
  • Arenal Volcano exploration
  • Relax in Ecotermales hot springs
  • Pearl Islands snorkeling
  • Navigate the Panama Canal
Starts / Ends
San Jose / Panama City
Activities
Land & Sea Exploration
Activity Level
Variable
Arrive in San Jose, transfer to La Fortuna and start the 9-day land and sea adventure. Explore Arenal Volcano and rainforest trails. Fly to Panama City and embark National Geographic Quest. Kayak, hike, and cruise the Panama Canal, Gatun Lake, and Pearl Islands while snorkeling, exploring fortresses, and discovering tropical wildlife.
Cruise Details
0
Boats Moored to the Quay at Bridgetown Harbour
from $4,450
EXPLORE

Barbados to Panama

15 Day Itinerary aboard Royal Clipper
  • Explore Bridgetown, Barbados
  • Enjoy Grenada's unique aromas
  • Discover Dutch colonial Curacao
  • Transit the historic Panama Canal
Starts / Ends
Bridgetown / Balboa
Activities
Small Ship Sailing
Activity Level
Variable
Starting at the Caribbean port of Bridgetown, this 15-day cruise aboard the Royal Clipper sails through the turquoise Caribbean waters en route to the Panama Canal, visiting Grenada, Bonaire, Curacao, Aruba, and Colombia along the way. Explore the tropical jungles, snorkel in vibrant reefs, immerse yourself in tribal culture, and marvel at the Panama Canal.
Cruise Details
0
1-12 of 27 Results

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