Top Panama Tours & Cruises in 2028

Arrive in San Jose, transfer to La Fortuna and start the 9-day land and sea adventure. Explore Arenal Volcano and rainforest trails. Fly to Panama City and embark National Geographic Quest. Kayak, hike, and cruise the Panama Canal, Gatun Lake, and Pearl Islands while snorkeling, exploring fortresses, and discovering tropical wildlife.

Experience a 12-day cruise on the Douglas Mawson, exploring the diverse coastlines of Costa Rica and Panama. Discover lush rainforests, vibrant marine life, and enjoy a daylight passage through the iconic Panama Canal.

Set sail on a 12-day Caribbean cruise from Bridgetown aboard the Emerald Azzurra, exploring islands like Bequia and Mayreau. Conclude your journey in Panama City after traversing the historic Panama Canal and enjoying vibrant local cultures and stunning coastal views.

Set sail on a 12-day Caribbean cruise from Bridgetown aboard the Emerald Azzurra, exploring islands like Bequia and Mayreau. Conclude your journey in Panama City after traversing the historic Panama Canal and enjoying vibrant local cultures and stunning coastal views.

This Panama City one-day tour takes you on the incredible journey from the Atlantic Ocean all the way to the Pacific Ocean, traversing two impressive locks via the manmade wonder that is the Panama Canal.

Climb aboard and experience the "Eighth Wonder of the World" first hand as you transit through the Miraflores Locks to the Pacific Ocean.

Tour Panama City with a local guide, well versed in the history of the area. See a transit of the Panama canal and tour Casco Antiguo where the pirate Henry Morgan waged his attack in 1671.

Visit Barro Colorado Island while in the Panama City with a boat ride in Gatún Lake. Enjoy a day exploring the Smithsonian Tropical Research Institute and learn about the current studies underway. This man-made island was created when the canal was flooded preserving a breathtaking array of diverse wildlife and jungle on the tiny island.

Drive from Panama City to El Valle: hike, zipline above El Macho Falls, explore the market, enjoy lunch & thermal pools.

Visit Aguas Clara Visitor Center for stunning Gatun Lake views and marvel at the historic San Lorenzo Fort. Explore scenic landscapes, rich wildlife, and Panama Canal expansion highlights in one action-packed day.

Experience native Panamanian culture deep in the Chagres rainforest. Visit with the people of the Embera Dura community and hike through the jungle with your guide.