Have questions? We're here.
Iguazu Falls on Argentina vacation

Best South American River Cruises

Travel made your way
Talk with an expert
Build your ideal South America trip. Call 1.406.541.2677
Start Planning My Trip
Filter (50 Results)
  • Start Date
    OR, More specific start
  • Length
    to
  • Price
    to
  • Activity Levels
  • Experiences
  • Activities
  • Ships
  • Destinations
    • South America
Riding a traditional canoe down the river
from $3,060
EXPLORE

Amazon Wildlife & Culture Journey

Iquitos Roundtrip - 7 Day Itinerary aboard La Perla
  • See pink and grey dolphins play
  • Meet and visit with locals
  • Admire the Amazon wildlife
  • Visit the birth place of the Amazon
Starts / Ends
Iquitos / Iquitos
Activity Level
Variable
This week-long river cruise onboard La Perla is ideal for flora and fauna enthusiasts who want to experience the Amazon rainforest. This region of the world is a birding enthusiast's paradise. Also, witness pink river dolphins in a way you've never seen them before.
Cruise Details
0
Beauty of Amazon River
from $4,178
EXPLORE

Amazon Journey via Marañón River- High Water Season

Iquitos to Nauta - 5 Day Itinerary aboard Zafiro
  • Visit the birth place of the Amazon
  • Kayak and swim in the Amazon River
  • Meet and visit with locals
Starts / Ends
Iquitos / Nauta
Activity Level
Variable
Set sail towards the Sapote River, a protected area of the Pacaya-Samiria National Reserve, on a 5-day Amazon cruise on the Zafiro. As translators for indigenous people, naturalist guides utilize their eagle eyes to help you spot and learn about Amazonian species.
Cruise Details
0
Looking up the trunk of a giant rainforest tree
from $8,034
EXPLORE

Amazon Journey - High Water Season

Iquitos Roundtrip - 8 Day Itinerary aboard Zafiro
  • See the birthplace of the Amazon
  • Take a nocturnal boat ride
  • Meet and interact with locals
  • Swim in the Amazon River
Starts / Ends
Iquitos / Iquitos
Activity Level
Variable
Join the Zafiro on this 8-day journey showcasing the mighty Amazon River’s treasures. Navigate deep into Pacaya Samiria Reserve for a real and safe adventure to spot the wonderful creatures of the Amazon!
Cruise Details
0
Mompox, Colombia
from $3,749
EXPLORE

Magic of Colombia - Cruise Only

Barranquilla - Cartagena - 8 Day Itinerary aboard AmaMagdalena
  • Experience Barranquilla’s Carnaval
  • Explore Sitio Nuevo’s village life
  • Discover Boca de Tacaloa landscapes
  • Stroll Mompox’s colonial streets
Starts / Ends
Cartagena / Cartagena
Activity Level
Variable
Embark on an 8-day cruise along Colombia's Magdalena River from Barranquilla to Cartagena on the AmaMagdalena. Enjoy vibrant music, local coffee, unique wildlife, and authentic cultural experiences, including a private Carnaval celebration.
Cruise Details
0
Mary in Colombia, View of Medellin from coffee plantation_
from $4,049
EXPLORE

Magic of Colombia

Barranquilla - Cartagena - 8 Day Itinerary aboard AmaMelodia
  • Experience Carnaval of Barranquilla
  • Visit Sitio Nuevo artisan crafts
  • Tour Boca de Tacaloa wetlands
  • Enjoy Mompox jazz performance
Starts / Ends
Cartagena / Cartagena
Activity Level
Variable
Experience an 8-day river cruise along Colombia's Magdalena River from Barranquilla to Cartagena on the AmaMelodia. Enjoy Carnaval festivities, explore artisan towns, and immerse yourself in local culture with music, dance, and historic tours.
Cruise Details
0
Cartagena Old Town
from $4,049
EXPLORE

Wonders of Colombia

Cartagena - Barranquilla - 8 Day Itinerary aboard AmaMelodia
  • Experience Palenque’s rich culture
  • Celebrate Barranquilla Carnaval
  • Visit Santa Bárbara artisans
  • Ride Calamar’s historic paola
Starts / Ends
Cartagena / Cartagena
Activities
Local Market Visits, Wildlife Viewing, Village Visits, Festival Visits, Urban Exploration
Activity Level
Variable
Discover Colombia's wonders on an 8-day cruise along the Magdalena River aboard AmaMelodia. Visit Palenque, the first free city, and the vibrant Getsemaní neighborhood in Cartagena. Discover the blend of cultures, music, and art that define the country.
Cruise Details
0
View the abundant wildlife of the Amazon
from $3,743
up 30% off
EXPLORE

Amazon Discovery

5 Day Itinerary aboard M/V Anakonda
  • Learn about the Amazon's diversity
  • Visit an Authentic Indigenous home
  • Navigate pristine water sections
Starts / Ends
Coca / Yasuni National Park
Activities
Hiking
Activity Level
Variable
Embark on an Amazon River cruise aboard the M/V Anakonda. This luxury small-ship vessel takes you to the heart of the Ecuadorian Amazon to see the pink river dolphin, black caiman, and anaconda in their natural habitat. Keep an eye out for crocodiles, monkeys, and hoatzins in the river.
Cruise Details
0
Pink dolphin
from $4,650
EXPLORE

Voyage to the Heart of the Amazon

Roundtrip Manaus - 7 Day Itinerary aboard Tucano
  • Enjoy daily walks and swimming time
  • Observe magnificent plants
  • Listen for bird and mammal calls
  • Look for caimans in the river
Starts / Ends
Manaus / Manaus
Activity Level
Variable
Experience a 7-day Amazon River cruise on the M/Y Tucano, starting from Manaus and exploring the Rio Negro's untouched ecosystems. Engage in daily excursions, including rainforest walks while discovering diverse wildlife and learning from expert naturalists.
Cruise Details
0
Capybaras in the water
from $2,800
EXPLORE

Amazon Wildlife & Culture Journey

Nauta Roundtrip - 7 Day Itinerary aboard Amatista
  • See pink and grey dolphins play
  • Meet and visit with locals
  • Admire the Amazon wildlife
  • Visit the birth place of the Amazon
Starts / Ends
Iquitos / Nauta
Activities
Rainforest Exploration, Kayaking
Activity Level
Variable
This week-long river cruise onboard Amatista is ideal for flora and fauna enthusiasts who want to experience the Amazon rainforest. This region of the world is a birding enthusiast's paradise. Also, witness pink river dolphins in a way you've never seen them before.
Cruise Details
0
A lovely reflection off the Amazon River
from $5,000
EXPLORE

Luxury Amazon Explorer - High Water

Roundtrip Nauta - 5 Day Itinerary aboard Aria Amazon
  • Explore the Ucayali River
  • Navigate the Zapote River
  • Tour Nauta’s local market
  • Explore the Yarapa River by skiff
Starts / Ends
Iquitos / Nauta
Activity Level
Variable
Embark on a 5-day cruise through the Peruvian Amazon aboard the Aria Amazon, starting with a city tour in Iquitos. Experience the rich biodiversity with river excursions, rainforest hikes, and opportunities to engage with local communities, ending with a visit to the Manatee Rescue Center in Nauta.
Cruise Details
0
Giant lily pads on the Amazon River
from $3,856
EXPLORE

Amazon Journey via Ucayali River- Low Water Season

Iquitos to Nauta - 4 Day Itinerary aboard Zafiro
  • Visit the Mirrored Forest
  • See pink and grey dolphins play
  • Explore the black water streams
Starts / Ends
Nauta / Nauta
Activity Level
Variable
Explore the Amazon, Ucayali, and Pacaya Rivers on their way deep into the Pacaya Samiria Reserve, one of Peru´s largest national parks. Go piranha fishing, trek into the dense jungle in search of Amazon wildlife and birds, take a night safari and guided trips, visit local villages, and learn about wildlife preservation efforts in Peru’s Amazonia.
Cruise Details
0
Tree frog spotted in the Amazon
from $4,178
EXPLORE

Amazon Journey via Marañon River- Low Water Season

Nauta to Nauta - 5 Day Itinerary aboard Zafiro
  • Visit the birth place of the Amazon
  • Kayak and swim in the Amazon River
  • Meet and visit with locals
Starts / Ends
Iquitos / Nauta
Activities
Fishing
Activity Level
Variable
Embark on a 5-day cruise aboard Zafiro exploring the wonderful Amazon and its tributaries towards the Sapote River, a buffered zone of the Pacaya-Samiria National Reserve. Naturalist guides use their eagle eyes to help you spot extraordinary wildlife and act as interpreters so that you may learn from Amazonian communities.
Cruise Details
0
37-48 of 50 Results

Let us match you to your best adventure.

Talk with an expert trip planner 1.800.344.6118

Plan My Trip
Jane Packer Adventure Life employee profile
Jane P.
Peruvian weavers
South America

Chat South America with a specialist

Our team is waiting and ready to talk with you about your next adventure. So go ahead and book an appointment with one of our specialized trip planners.

Let's Chat
1.800.344.6118

Where is your next adventure?

Contact Chat Call
More Reasons

Why Travel With Adventure Life

All News

Featured In

How it Works

Connect

No cost, no commitment. Talk with our experts about your dream trip.

Plan

Share your travel style—we match you with the right itinerary or create one just for you.

Book

Lock in knowing every detail is handled and you’re fully supported.

Travel

Enjoy a seamless journey—and unlock 5% off your next adventure.

South America Travel Guide

Favorite South America South America All Trips

Top South America Travel Destinations

South America Trips by Departure Date

Top Experiences in South America

South America Trips by Duration

South America Trips by Activity