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Top South America Tours & Cruises in 2027

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San Pedro Claver Plaza, Cartagena
from $3,234
EXPLORE

Colombia Highlights

Bogota to Cartagena - 9 Day Itinerary
  • Explore the vibrant city of Bogota
  • Visit churches in Bogota
  • Discover Salamina with your guide
  • Visit Hacienda Venecia coffee farm
  • Visit Cartagena's historical sites
  • Swim and snorkel in Tierra Bomba
Starts / Ends
Bogota / Cartagena
Activities
Hacienda Visits, Homestays
Activity Level
Relaxed
Enjoy a complete 9-day tour discovering the highlights of Colombia. Dance the salsa and explore the city of Bogota, visit the Wax Palm reserve in Salamina, and taste the best coffee in Manizales. Finally, discover the rich culture preserved in Cartagena. Visit multiple parts of Colombia and see the best that each place has to offer.
Tour Details
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The colorful streets of Cartagena
from $3,166
EXPLORE

Bogota to Cartagena Adventure

7 Day Itinerary
  • Visit iconic and landmark in Bogota
  • Visit Monserrate Church
  • Stroll in La Candelaria
  • Visit Cartagena's historical sites
  • Explore Rosario Islands
  • Visit San Basilio de Palenque
Starts / Ends
Bogota / Cartagena
Activities
Local Market Visits
Activity Level
Easy Active
On this 7-day Colombia tour, discover Bogota and Cartagena. Visit the most iconic and historical landmarks in Bogota and walk down the cobblestone streets of La Candelaria. Fly to Cartagena and see the beautiful beaches on the Caribbean coast. Take a walking tour and see the beautiful plazas and monument walls of historic Cartagena
Tour Details
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The breathtaking Amazon River
from $2,542
up 20% off
EXPLORE

Amazon Exploration

4 Day Itinerary aboard Manatee
  • Visit the parrot clay licks
  • Learn Amazon traditions and cuisine
  • Observe nocturnal wildlife
Activity Level
Variable
Take the M/V Manatee on a 4-day Amazon River cruise. Travel from Quito to Coca, explore Pañacocha Lake, see parrot clay licks, and visit Kichwa communities. Enjoy guided walks, canoe rides, and kayaking in one of the world’s richest ecosystems.
Cruise Details
0
from $1,692
EXPLORE

Medellin Adventure

5 Day Itinerary
  • Explore the vibrant city of Medelli
  • Visit the city of Guatapé
  • Taste tropical fruits and coffee
  • Visit local coffee farm
  • Learn about coffee in Concordia
Starts / Ends
Medellin / Medellin
Activity Level
Easy Active
Spend your week getting to know Medellin on this 5-day tour, including an in-depth city tour and a coffee plantation tour in the town of Concordia. Learn about Medellin and experience what its culture has to offer. Enjoy the scenery, and the colorful tiled streets, and taste tropical fruits and coffee
Tour Details
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Guanaco in Torres del Paine
from $12,599
EXPLORE

South America Grand

34 Day Itinerary
  • Observe toucans and macaws
  • Snorkel among Galapagos marine life
  • Watch water flood over Iguazu Falls
  • Hike to the spires of El Paine
Activities
Wilderness Lodge Exploration, Biking, Cooking Classes
Activity Level
Relaxed
Explore the best of South America on this month-long adventure that begins in Ecuador and ends in Chile. This itinerary has it all from snorkeling, hiking, and searching for wildlife to cultural immersion, food tasting, and history. This itinerary takes you to the Galapagos, Machu Picchu, Iguazu Falls, and Easter Island, just to name a few.
Tour Details
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Aerial view of Christ the Redeemer and Sugarloaf Mountain
from $12,680
EXPLORE

Rhythms of the Brazilian Coastline

Buenos Aires - Rio de Janeiro - 12 Day Itinerary aboard Scenic Eclipse
  • Visit Punta del Este golden beaches
  • Spot Ilhabela capuchin monkeys
  • Walk Paraty cobbled streets
  • Enjoy Rio de Janeiro beaches
Starts / Ends
Buenos Aires / Rio de Janeiro
Activities
Village Visits, Wildlife Viewing, Urban Exploration, Snorkeling
Activity Level
Variable
Experience a 12-day cruise from Buenos Aires aboard the Scenic Eclipse, visiting eight vibrant Brazilian ports. Engage in guided activities and cultural excursions while exploring lush coastlines and native wildlife.
Cruise Details
0
Sea and stone formations in Galapagos
from $12,470
EXPLORE

East Galapagos

Baltra - Santa Cruz - 8 Day Itinerary aboard Aqua Mare
  • Observe a variety of wildlife
  • Explore El Barranco
  • Discover Bahía Sullivan lava flows
  • Enjoy views of iconic Pinnacle Rock
Starts / Ends
Baltra / Osborn Islet
Activities
Kayaking, Stand Up Paddle Boarding
Activity Level
Variable
Immerse yourself in a pristine ecosystem rich with endemic wildlife on this 8-day East Galapagos cruise aboard Aqua Mare. Visit Playa Las Bachas, El Barranco, Bahía Sullivan, Cerro Dragón, El Chato Giant Tortoise Reserve, Punta Suarez, and Santa Fe.
Cruise Details
0
from $3,795
EXPLORE

Cerro Castillo Hike

5 Day Itinerary
  • Visit Laguna Verde and Morro Negro
  • Experience Neozelandes basecamp
  • Explore glacial lake Laguna Duff
  • Experience Chile's Aysen region
Starts / Ends
Balmaceda / Villa Cerro Castillo
Activities
Hiking, Horseback Riding
Activity Level
Moderate
Explore Patagonia on a 5-day Cerro Castillo trek in Chile’s Aysen region. Hike to Neozelandes basecamp, climb to Laguna Verde and Morro Negro, and visit hidden Laguna Duff. Enjoy native forests, alpine views, and wildlife. Includes local lodging, campsite meals, and transfers from Villa Cerro Castillo to Balmaceda Airport.
Tour Details
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Canopy walk through the heart of the rainforest
from $1,750
EXPLORE

Amazon Journey via Ucayali River

Iquitos Roundtrip - 4 Day Itinerary aboard La Perla
  • See pink and grey dolphins play
  • Visit the birth place of the Amazon
  • Meet and visit with locals
Starts / Ends
Iquitos / Nauta
Activities
Rainforest Exploration
Activity Level
Variable
La Perla hosts this 4-day Amazon cruise from Iquitos. Explore the Amazon, Ucayali, and Pacaya Rivers on their way deep into the Pacaya Samiria Reserve. Trek into the dense jungle in search of Amazon wildlife and birds, take a night safari and guided trips, visit local villages, and learn about wildlife preservation efforts in Peru’s Amazonia.
Cruise Details
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Woman jumping! Salar de Uyuni
from $2,954
EXPLORE

Uyuni and Colored Lagoons

5 Day Itinerary
  • View pink flamingos in the desert
  • See ancient mummies in the museum
  • Visit Uynui Salt Flats
Starts / Ends
La Paz / La Paz
Activities
Archaeological Site Visits
Activity Level
Easy Active
This 5-day tour will give you a taste of Bolivia's geological diversity from volcanoes to ancient salt flats. Explore the region of Uyuni famous home of the world's largest salt flats, visible from space, before traveling south where the lagoons are vibrantly colored from the thermal activity.
Tour Details
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River in the Amazon Rainforest
from $6,000
EXPLORE

Amazon Discovery - High Water Season

Nauta - Iquitos - 4 Day Itinerary aboard Delfin Amazon Cruises
  • Visit Amazon Natural Park
  • Kayak Yanayacu River
  • Join an Amazon piranha fishing
  • See Fundo Casual wildlife
Starts / Ends
Iquitos / Iquitos
Activities
Fishing
Activity Level
Variable
Sail through the Amazon on a 4-day cruise aboard Delfin I from Iquitos to Nauta. Explore flooded forests, meet local communities, spot pink dolphins, and visit the Amazon Natural Park. Experience guided excursions, unique wildlife, and cultural encounters in one of the world’s most biodiverse regions.
Cruise Details
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Sea lion and scuba diver
from $4,590
EXPLORE

North and West Islands - Diving Itinerary

Santa Cruz to North Seymour - 8 Day Itinerary aboard Danubio Azul
  • Dive at Darwin’s Arch
  • Walk North Seymour trails
  • Discover Cousin’s Rock
  • Snorkel at Vicente Roca Point
Starts / Ends
Baltra / Baltra
Activities
Scuba Diving
Activity Level
Variable
Dive into the world-renowned waters of the Galapagos on this 8-day cruise aboard Danubio Azul. This liveaboard expedition explores remote diving sites including Darwin’s Arch, Wolf Island, and Cape Marshall. Discover some of the planet’s richest marine ecosystems on this unforgettable adventure.
Cruise Details
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Karilyn O.
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