Top South America Trips & Tours in October 2026

Salta province in Northwest Argentina has the culture and scenery to fascinate any inquisitive traveler. Explore the stunning rock formations of Valles Calchaquies, the colonial history of Salta, the archeology of Cachi, and Cafayate's rich wines and cuisine.

On this 4-day tour you'll hike and paddle through the Tierra del Fuego National Park, sail the Beagle Channel, and explore Estancia Harberton and penguin rookeries with thousands of penguins from our base in Ushuaia, Argentina. One of our favorite trips to Argentine Patagonia, and a highly recommended extension to an Antarctic cruise.

This active 5-day tour of Lake Titicaca in Peru puts kayaking at the heart of the experience, allowing you to explore the largest and highest lake in South America in a truly unique way, while enjoying the cultural intimacy offered by a homestay with a local family whose roots go back to ancient times.

Explore the Peruvian Amazon on this 5-day Ceiba Tops Lodge trip. Travel 25 miles downstream on the Amazon River to your beautiful sanctuary lodge with air-conditioned cabins and hot water showers. Observe Amazon wildlife and vegetation from a 115-foot Canopy Walkway, an unequaled experience!

Explore Peru's vast jungle with a 3-night stay at Ceiba Tops Lodge. Make your way to Iquitos, the headwaters of the Amazon, and travel down the river to your jungle home. Visit an indigenous community and view wildlife from the canopy during your stay.

Embark on a 15-day Islands Circumnavigation cruise to Santa Cruz, Fernandina, Isabela, Santiago, Rabida, Bartolome, Genovesa, San Cristobal, Espanola, Floreana, and more! This comprehensive voyage on the Seaman Journey highlights the best of the Galapagos archipelago and treats travelers to amazing scenery and wildlife viewing.

Journey to the Northern Islands of the Galapagos on this 9-day cruise aboard the Seaman Journey. Discover the wonders of the Galapagos Islands, from volcanic landscapes to vibrant wildlife.

Join this 8-day Patagonia culture and nature adventure, a combination of unique wildlife, cultural immersion and spectacular scenery in the heart of Chilean Patagonia. Explore Torres del Paine National Park and choose your activities each day based on your preferences and interests.

Experience the ultimate 15-day adventure through the Guianas. Discover Guyana's Kaieteur Falls and Rupununi wildlife, Suriname's UNESCO-listed Paramaribo and Maroon culture, and French Guiana's Space Center and Devil's Island. This tour blends pristine nature, rich history, and diverse cultures across three unique territories.

Explore the natural wonders of Guyana on a 15-day adventure. Visit Georgetown, Iwokrama River Lodge, and Atta Rainforest Lodge for wildlife spotting and trail walking. Experience Rewa Eco-Lodge and Karanambu for cultural insights and wetland exploration. Witness Giant Anteaters on the savannah and enjoy nocturnal river excursions.

Experience Colombia’s rich culture and scenery on this active 12-day trip from Bogotá to the Caribbean coast. Hike to the Lost City, visit colonial towns like Villa de Leyva and Barichara, and unwind in Tayrona National Park’s pristine beaches. Explore Cartagena’s UNESCO-listed charm while connecting with Colombia’s diverse landscapes and heritage.

Discover the Torres del Paine National Park with luxury accommodations and unique excursions. Enjoy a 7-day relaxing stay at Awasi Patagonia while you explore the national park by horseback, foot, or kayaking nearby lakes on this eco-tour.