Top South America Trips & Tours in September 2026

Explore the best of South America on this month-long adventure that begins in Ecuador and ends in Chile. This itinerary has it all from snorkeling, hiking, and searching for wildlife to cultural immersion, food tasting, and history. This itinerary takes you to the Galapagos, Machu Picchu, Iguazu Falls, and Easter Island, just to name a few.

Explore Patagonia on a 5-day Cerro Castillo trek in Chile’s Aysen region. Hike to Neozelandes basecamp, climb to Laguna Verde and Morro Negro, and visit hidden Laguna Duff. Enjoy native forests, alpine views, and wildlife. Includes local lodging, campsite meals, and transfers from Villa Cerro Castillo to Balmaceda Airport.

This 5-day tour will give you a taste of Bolivia's geological diversity from volcanoes to ancient salt flats. Explore the region of Uyuni famous home of the world's largest salt flats, visible from space, before traveling south where the lagoons are vibrantly colored from the thermal activity.

La Perla hosts this 4-day Amazon cruise from Iquitos. Explore the Amazon, Ucayali, and Pacaya Rivers on their way deep into the Pacaya Samiria Reserve. Trek into the dense jungle in search of Amazon wildlife and birds, take a night safari and guided trips, visit local villages, and learn about wildlife preservation efforts in Peru’s Amazonia.

Spend two weeks exploring the undiscovered northern regions of Brazil on this active & remote vacation that shows you the authentic side of the Brazilian lifestyle. This tour combines trekking through the sand dunes of Lencois Maranhenses National Park, the beach sports mecca of Jericoacoara, and the isolated tropical paradise Fernando de Noronha.

This 12-day Black Diamond Trek to Machu Picchu invites you to discover Peru's wonders. Explore off-the-beaten-path trails from Cusco to the iconic ruins. Trek through hidden mountains, villages, and ancient sites. Indulge in luxury camping, kayak pristine lakes, and savor traditional Pachamanca dinners.

Explore the colonial town of Cusco, and trek to the ruins of Choquequirao. The ruins can only be visited by two days or hiking so you'll be enjoying them with few other visitors. Visit with locals, wander through local markets, and tour Machu Picchu on this 12-day exploration. This active trek is challenging and rewarding all at the same time!

Combine 8 days in the Galapagos with a trip to Peru and Machu Picchu. Explore Cusco, and the Sacred Valley, and spend two days discovering Machu Picchu learning about the ancient ways of the Incas and the traditions of Andean people today. Then fly to the Galapagos Islands for 8 days of wildlife & natural discovery!

Experience an exciting 8-day Avenue of Volcanoes adventure trip. Hike, and witness stunning views of Cotopaxi, Quilotoa Lake, and Chimborazo. Explore Llanganates National Park, indulge in outdoor activities in Baños, and visit captivating waterfalls. Conclude in Quito City.

Visit La Paz and experience the local Bolivian culture on this week-long journey! Explore Lake Titicaca, a geographic landmark at the crossroads of the Andes and the Andean plateau and home to the ruins of Tihuanaco and remnants of Inca temples at Sun and Moon Islands. This is the world's highest navigable lake.

Join this 8-day Amazon safari adventure from the Andes to the lush jungles of Puerto Maldonado and the remarkable Manu Biosphere Reserve. Journey deep into one of South America’s largest protected areas and explore the remote Manu Wildlife Center. Complete your Peru adventure with two days in colonial Cusco, immersing yourself in rich Andean culture and history.

Enjoy an amazing 4-day cruise exploring the highlights of the Norhern Islands of the Galapagos archipelago, including Santa Cruz, Santiago, Genovesa, and Rabida, aboard Nemo II