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La Crosse, Wisconsin River Cruises

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Experience the natural beauty and charm of La Crosse on one of Adventure Life's 3 invigorating river cruises in 2025. Nestled along the Mississippi River, La Crosse offers a unique blend of outdoor adventures and cultural experiences. Sail through picturesque landscapes, explore quaint villages, and indulge in delicious local cuisine. Discover the region's rich history, vibrant wildlife, and stunning scenery during your 12 to 16 days river cruise. Whether you're interested in wildlife viewing, hiking, or simply relaxing on deck, La Crosse has something for everyone. Join us on a trip to La Crosse and contact one of our award-winning river cruise experts for help planning your next seamless adventure.
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    • La Crosse
View the iconic arch when you visit St. Louis, gateway to the west
$12,999
EXPLORE

America’s Great River

St. Paul to New Orleans - 15 Day Itinerary aboard Viking Mississippi
  • Explore St. Louis' arts scene
  • Enjoy American music styles
  • Learn Civil War history
  • Experience New Orleans' culture
  • Visit the Quad Cities
Starts / Ends:
St. Paul / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Village Visits
Activity Level:
Variable
Discover the history, natural beauty, and distinctive regional cultures of America's great river, the mighty Mississippi, on this 15-day cruise aboard Viking Mississippi. Set sail from St. Paul, Minnesota, and venture south toward New Orleans, Louisiana. Along the way, visit small towns and …
Cruise Details
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Vibrant Sunset with St. Paul City Skyline and Mississippi Riverfront
$11,755
Savings
EXPLORE

Grand Heartland Cruise

Minnesota - Louisiana - 16 Day Itinerary aboard American Serenade
  • Visit mansions and art galleries
  • See the Gateway Arch and St. Louis
  • Visit Natchez’s antebellum homes
  • Experience Memphis' musical legacy
Starts / Ends:
St. Paul / New Orleans
Activities:
Village Visits
Activity Level:
Variable
Embark on a 16-day cruise aboard American Serenade and begin by exploring St. Paul's art galleries and historic Summit Avenue. In La Crosse, enjoy Riverside Park and panoramic views from Grand Dad’s Bluff. Discover Dubuque, with its Victorian mansions and the Mississippi River Museum …
Cruise Details
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The upper Mississippi region
$6,999
EXPLORE

America’s Heartland

St. Louis to St. Paul - 12 Day Itinerary aboard Viking Mississippi
  • Discover history of the Mississippi
  • Explore Dubuque, Iowa
  • Experience Mississippi river towns
  • Admire local artisan work
Starts / Ends:
St. Louis / St. Paul
Activities:
Archaeological Site Visits, River Cruises, Village Visits
Activity Level:
Variable
On this enlightening journey on the Upper Mississippi, hear stories of pioneers and the Lewis and Clark Expedition; walk in the footsteps of Mark Twain; and learn about the Norwegian migration. Enjoy the view as your ship navigates through the river’s intricate lock system. Experience the …
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