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Louisville to St. Louis (Alton)

Example 9 Day Cruise aboard American Queen
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Board the American Queen riverboat and cruise through the heart of the American Midwest on this 9-day journey from Louisville, Kentucky to St. Louis, Missouri on the Ohio and Mississippi Rivers. Experience the laid-back, small-town hospitality of Kentucky ports such as Owensboro, where you'll find classic folk tunes and distilleries making Kentucky's signature bourbon, or Henderson, where you can explore the region's role in the Civil War. Admire historic handicrafts at the National Quilt Museum in Paducah, Kentucky, and follow in the footsteps of historical figures like Mark Twain and the Lewis & Clark expedition in Cape Girardeau, Missouri. Your journey concludes in St. Louis, Missouri, where you'll find a wealth of museums, foodie hot spots, and, of course, the famous arch marking the gateway to the west. 
Try classic Kentucky bourbonAmerican queen2Visit historic St. Louis
Highlights
  • Sip classic cocktails made with locally-distilled Kentucky bourbon
  • Explore the vibrant art scene and foodie hot spots of St. Louis
  • Enjoy lively folk music in the community of Owensboro
  • Admire historic handicraft at the National Quilt Museum
Activity Level: Relaxed
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Full Itinerary

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Day 1: Louisville, Kentucky

Enjoy your complimentary stay at the pre-cruise hotel. The evening is yours to become acquainted with the city. Our Hospitality Desk will be located in the hotel, and our friendly staff can assist with everything from general questions about your upcoming voyage to reserving premium experiences. Both American Queen Steamboat Company and local representatives will be readily available to provide you with dining, entertainment and sightseeing options to maximize your time here.

Day 2: Louisville, KY | Embark

  • Ship
  • 1 Breakfast, 1 Dinner
This authentically quirky port is a muse to artisans of mixed mediums – from sidewalk chalk to street fare – and home to the cultural diversity that quickly captivates the heart of its visitors. The local tradition that lives within images of Derby hats, Old-Fashioned cocktails and the 120-foot Louisville Slugger that towers over the friendly city are better lived than seen. Explore the red penguin-peppered Main Street. Embrace oddity. Experience Louisville. 

Day 3: Brandenburg, KY

  • Ship
  • 1 Breakfast, 1 Lunch, 1 Dinner
The essence of Kentucky radiates, from its bourbon traditions to a tableau of rolling farmland. Soul-stirring river views and Southern warmth welcome those who pursue relaxation. Mysteries of the Civil War enlist lifelong learners on the battlefield while sprawling parks and trails make way for recreation. The grass is bluer in Brandenburg and all the surrounding areas. 

Day 4: Owensboro, KY

  • Ship
  • 1 Breakfast, 1 Lunch, 1 Dinner
The exuberance that pervades the sounds of folk music flows through the community of Owensboro. Each of its spaces is a lovely ballad that tugs at the heartstrings of visitors – from the notes of bourbon distilleries to bumbling butterflies in the botanical garden. The tawny banks of this river jewel extend a warm welcome, and invite you to experience the beauty in bluegrass. 

Day 5: Henderson, KY

  • Ship
  • 1 Breakfast, 1 Lunch, 1 Dinner
Capture your inner artisan in the home of James Audubon and W.C Handy. Hospitality flows freely through a vibrant downtown that kisses the rolling river. Wide streets welcome guests and showcase historic preservation that awakens a classic ambiance in storefronts and homes. Discover nature fingerprinted with humanity in the many parks and trials that showcase artistry throughout the town. Greetings from Henderson – a walkable community wrapped in warmth. 

Day 6: Paducah, KY

  • Ship
  • 1 Breakfast, 1 Lunch, 1 Dinner
In the hands of artists, modern Paducah was thrown into form. Fingertips muddied with passion and eased by the vision of river water glided along the surface to pull up the community and create the National Quilt Museum. Residents backstitch past into present, then bind appreciation for culture – ensuring that the seams of history will not soon come undone. The people of Paducah have taken great care to orchestrate every crevice of its community into a symphony of craft and color. Life is a work of art, and the town of Paducah certainly is alive and well. Feast in this foodies’ fantasy. Uncover mastership. Catch a glimpse of Paducah. 

Day 7: Cape Girardeau, Missouri

  • Ship
  • 1 Breakfast, 1 Lunch, 1 Dinner
Cape Girardeau has shown hospitality to the likes of Mark Twain, Meriwether Lewis and William Clark, and now greets our guests in the same vein. Peeking through the long-standing architecture and handsome panoramas are moments that will mature into golden memories. They say sometimes the little things make the biggest impact, and here, a million little things have built an empire. Take time to dance among the light of day or pedal along the sliver of bike lanes that strip along city streets. Embrace legends, discover a simpler time and relive the wonders of the past. Here, exploration of young America is at your fingertips. 

Day 8: River Cruising

  • Ship
  • 1 Breakfast, 1 Lunch, 1 Dinner
Strategically placed above our docking area on the Chickasaw Bluffs is Fort Pillow – where rest the silenced voices of the Civil War. The smoke has cleared to shed light on the pogrom that transpired in this decisive point. It is here that the Fort Pillow Massacre took the lives of 221 Confederate soldiers, and experienced historians resurrect stories misplaced in the tumult of war.

Day 9: St. Louis, MO | Disembark

As the journey concludes, there are other opportunities for you to take in the town. Enjoy the city at your leisure, or consider an airport transfer.

Ship/Hotel

American Queen

American queen2
American Queen1
American Queen Relaxation

Dates & Prices

My Preferred Start Date

Per person starting at
$2,599
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Category E
Surrounded by wonderful period details, accompanied by every modern convenience, these cozy havens will make your cares disappear. Ample shelving and storage spaces keep necessities out of the way yet easily accessible. Has 132 sq. ft..
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Category SI
These intimate cabins with ample storage space are slightly scaled down to accommodate the independent traveler, and feature a single bed. Has 80 sq. ft.
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Category D
An expansive bay window overlooking the scenery of America’s heartland is the main draw of this spacious category. Curl up in front of the window with a new novel, and savor a moment that belongs to only you. Has 190 sq. ft. with bay window.
American Queen
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Category C
Open your French doors, and enjoy the fresh air. Sit on the deck outside your stateroom, and take in the gently changing views of the landscape, or indulge in a leisurely morning in bed with room service Has 140-160 sq. ft. with open veranda.
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Category B
Can you imagine opening French doors to a sweeping river vista and the sweet scent of magnolia trees? Sit on the deck outside your stateroom and greet early-morning strollers, relax in bed with your favorite book or soak in a hot bath. Has 190-205 sq. ft. with open veranda.
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Category A
With a private veranda, these staterooms are so enjoyable that you might decide to extend your journey. Relax in a cozy armchair and enjoy the view as you anticipate the activities of the day. Has 190 sq. ft. with 40-sq.-ft. private veranda.
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Category SD
Greet the day in your cozy stateroom, relaxing before breakfast, or simply enjoy a leisurely morning in bed with room service. Has 140 sq. ft.
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Category JS
Settle into your sitting area, open the French doors to the deck, and greet the day as the banks of the river majestically slip by. Some staterooms in this category offer a view of the paddlewheel, while others provide expansive views of America’s heartland. Has 210 sq. ft. with open veranda.
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Category PS
These spacious retreats offer unmatched views, each with a 6-foot-square viewing window that overlooks the paddlewheel, for a truly authentic steam boating experience. Stateroom 383: 342 sq. ft. Staterooms 385 and 386: 302 sq. ft.
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Category DS
You will feel right at home on the river in our magnificent suites. Indulge in a soothing soak in your tub, then retire to your cozy armchair or sofa, prop your feet up on the ottoman and read through the River Times – our daily program – to discover the delights that await. Has 230 sq. ft. with open veranda.
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Category LS
Our spacious, elegant suites are furnished to provide the warm ambiance of a fine Southern estate. Open your French doors and delight in sweeping river views as you sip a beverage and share conversation in your cozy sitting area. These suites are the ideal choice for family and friends vacationing together. 353-363 sq. ft. with private or open veranda
American Queen
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Category OS
Open French doors and step out onto your veranda to unwind on your amply furnished patio. Adorned with 11- foot vaulted ceilings, overhead lighting and a cozy interior lounging area with a sofa-bed and cocktail tables, these expansive suites can accommodate up to three guests, and epitomize luxurious river cruising. 348 sq. ft. with 690-sq.-ft. exclusive veranda
Included
  • 8 Breakfasts, 6 Lunches, 7 Dinners
  • 8 Nights Accommodations
  • Accommodations as listed
  • Ground transportation as listed
  • Excursions and activities as listed
  • Meals as listed
  • Beverages
  • Unlimited Free Wifi
  • One Night Pre-Cruise Hotel
  • Open Bars and Lounges
  • All-Day In-Room Dining
  • Bicycles & Hiking Sticks equipment if needed
  • Live, Daily Onboard Entertainment & Enrichment
  • Unlimited Included Expedition Adventures by Zodiac or Kayak (For Expedition Cruises Only)
Excluded
  • Travel Insurance
  • Personal Expenses
  • Flight costs (please request a quote)
  • Fuel and transportation surcharges (when applicable)
  • Arrival & Departure Transfers
  • Port Fees
  • Optional Premium Shore Excursions - highly recommend booking these in advance. If interested, ask us for a detailed list of premium excursions for your cruise as these vary depending on your departure date.
  • Mandatory Gratuities

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