Best Mississippi River Trips & Vacation Packages

Cruise aboard American Heritage on a 9-day cruise from New Orleans to Memphis along the Mississippi River. Visit Oak Alley, Baton Rouge, Natchez, Vicksburg, and Cleveland. Explore historic plantations, Civil War sites, blues landmarks, museums, and riverfront towns while experiencing the culture and history of the American South.

Discover the Mighty Mississippi on a 23-day cruise covering 10 states aboard American Melody. Immerse in history, culture, and cuisine from New Orleans to Minneapolis, exploring charming ports along the way.

Aboard American Symphony, cruise round-trip from New Orleans for 8 days through Louisiana and Mississippi. Tour antebellum mansions in Natchez, walk Vicksburg's Civil War battlefields, and take an optional swamp boat ride near Oak Alley — a good match for travelers drawn to Southern history and Cajun culture.

Embark on a 9-day cruise aboard American Heritage from Memphis to New Orleans along the Lower Mississippi River. Visit Cleveland, Vicksburg, Natchez, Baton Rouge, and Oak Alley. Explore Civil War landmarks, historic homes, museums, plantations, and Louisiana wetlands while discovering the history, music, and culture of the American South.

Take an 8-day Viking Mississippi cruise through Memphis, Cape Girardeau, Paducah, Clarksville, and Nashville. Visit key cultural and historical sites, from music landmarks to Civil War history and regional museums.

Cruise on a 9-day voyage aboard American Melody along the Mississippi River. Visit Cleveland, Vicksburg, Natchez, Baton Rouge, and Oak Alley through included excursions featuring museums, Civil War sites, historic homes, and music heritage. This itinerary combines Mississippi River scenery with Southern history and culture.

Experience a 9-day cruise aboard American Symphony from Memphis to New Orleans, discovering historic sites, Civil War stories, and charming towns along the Mississippi River. Experience rich history, music, and southern hospitality.

Experience a 9-day cruise aboard American Splendor from Memphis to New Orleans, discovering historic sites, Civil War stories, and charming towns along the Mississippi River. Experience rich history, music, and southern hospitality.

The American Melody hosts this 8-day Mississippi River cruise from New Orleans. Explore historic plantations, Civil War sites, and charming towns. Immerse in the rich culture, cuisine, and music of the Deep South.

Embark on a 16-day cruise linking two rivers, the Mississippi and Cumberland, between New Orleans and Nashville aboard American Symphony. Visit Civil War battlefields, antebellum estates, and the birthplaces of jazz, blues, and country music.

Explore a 16-day river cruise from Huntsville to New Orleans aboard American Heritage, following the Tennessee and Mississippi Rivers through Florence, Savannah, Paducah, Memphis, Vicksburg, Natchez, St. Francisville, Baton Rouge and Oak Alley, with historic sites, museums, music, Civil War history and Southern culture and historic cultural sites.

Explore New Orleans to Huntsville on a 16-day Mississippi River cruise aboard American Heritage. Visit historic estates, Civil War sites, music landmarks, museums, arts districts, and river towns while following the Mississippi and Tennessee rivers through Louisiana, Mississippi, Tennessee, Kentucky, and Alabama. Experience local traditions.