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Top Mississippi River Trips & Tours in September 2023

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New Orleans
Sean Pavone
Visit the famed Bourbon Street
St Louis
Sean Pavone
View the iconic arch when you visit St. Louis, gateway to the west
Vicksburg
Michael Warren
View a Civil War battlefields in Mississippi
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Discover Mississippi River in September 2023 on one of these 11 tours hand-selected by the travel experts at Adventure Life. Explore the best of St. Louis, Memphis, New Orleans, Vicksburg, and Nottoway during September 2023 as you enjoy archaeological site visits, village visits, and urban exploration. Prices for trips in September 2023 range from $1,999 to $103,999 for a vacation of 8 to 16 days. Choose any of the below 11 amazing itineraries in September 2023 and customize it to make it your own with the help of one of Adventure Life's expert Mississippi River trip planners.
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    • Mississippi River
Explore the rivers of America
$2,899
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St. Louis to Minneapolis

9 Day Itinerary aboard American Duchess
  • Explore the culture of St. Louis
  • See Mark Twain's hometown, Hannibal
  • Relax in laid-back La Crosse
  • Admire local artwork in Red Wing
Starts/ Ends in:
St. Louis / Red Wing
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Explore the land and river that inspired legendary American author Samuel Clemens, better known by his pen name, Mark Twain. Cruise northward from St. Louis, Missouri along the mighty Mississippi River, toward the city of Minneapolis. Along the way, explore port towns such as Hannibal, Missouri, …
Cruise Details
0
New Orleans paddlewheel steamer in New Orleans, Lousiana
$2,699
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New Orleans to Memphis

9 Day Itinerary aboard American Queen
  • Explore vibrant New Orleans
  • Experience the music of Memphis
  • Learn the history of Vicksburg
  • Explore Nottoway Plantation
Starts/ Ends in:
New Orleans / Memphis
Activities:
Archaeological Site Visits, River Cruises
Activity Level:
Relaxed
The Lower Mississippi River has stories to share – a legacy that flows from Memphis to the Gulf of Mexico. Embark on more than just a cruise, and return with more than memories: experience, understanding, an enlightened perspective. Explore the American South and discover all the great sights …
Cruise Details
0
Visit historic St. Louis
$2,699
Save 50%
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Memphis to St. Louis

9 Day Itinerary aboard American Queen
  • Listen to the music of Memphis
  • Explore wonders of New Madrid
  • Admire historic handicrafts
  • Explore the culture of St. Louis
Starts/ Ends in:
Memphis / St. Louis
Activities:
River Cruises, Village Visits
Activity Level:
Relaxed
Board the American Queen and join this delightful 9-day journey From the legacies that line the Mississippi River to the corners of creative genius along Ohio, your riverboat journey promises a wealth of eye-opening experiences and memories. Explore the seismic wonders of New Madrid and the iconic …
Cruise Details
0
View monuments from the Civil War in Mississippi
$5,799
EXPLORE

Minneapolis to New Orleans

16 Day Itinerary aboard American Duchess
  • Enjoy musical history in Memphis
  • Explore the arts in Minneapolis, MN
  • Discover St. Louis, Missouri
  • Admire the diversity of New Orleans
  • Learn about Civil War history
Starts/ Ends in:
Minneapolis / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Watch landscapes, cultures and even language transform as you cruise along the Mississippi river from Minneapolis to New Orleans aboard the American Duchess. Board this 16-day cruise to sail nearly the full length of the mighty Mississippi. Along the way, visit historic port cities and laid-back …
Cruise Details
0
$2,899
EXPLORE

New Orleans to Memphis

9 Day Itinerary aboard American Duchess
  • Discover St. Francisville
  • Experience the music of Memphis
  • Learn the history of Vicksburg
  • Explore vibrant New Orleans
Starts/ Ends in:
New Orleans / Memphis
Activities:
Archaeological Site Visits, River Cruises
Activity Level:
Relaxed
The Lower Mississippi River has stories to share – a legacy that flows from Memphis to the Gulf of Mexico. Embark on more than just a cruise, and return with more than memories: experience, understanding, an enlightened perspective. Explore the American South and discover all the great sights …
Cruise Details
0
Memphis, Tennesse, USA downtown cityscape at dusk over Beale Street
$2,699
EXPLORE

Memphis to New Orleans

9 Day Itinerary aboard American Queen
  • Admire the diversity of New Orleans
  • Discover the cultures of the delta
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts/ Ends in:
New Orleans / Memphis
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
The Lower Mississippi River has stories to share – a legacy that flows from Memphis to the Gulf of Mexico. Embark on more than just a cruise, and return with more than memories: experience, understanding, an enlightened perspective. Explore the American South and discover all the great sights …
Cruise Details
0
The upper Mississippi region
$4,899
EXPLORE

America’s Heartland

St. Louis to St. Paul - 8 Day Itinerary aboard Viking Mississippi
  • Discover history of the Mississippi
  • Explore Dubuque, Iowa
  • Experience Mississippi river towns
  • Admire local artisan work
Starts/ Ends in:
St. Louis / St. Paul
Activities:
Archaeological Sites, River Cruise, Village Visit
Activity Level:
Relaxed
On this enlightening journey on the Upper Mississippi, hear stories of pioneers and the Lewis and Clark Expedition; walk in the footsteps of Mark Twain; and learn about the Norwegian migration. Enjoy the view as your ship navigates through the river’s intricate lock system. Experience the …
Cruise Details
0
$2,499
EXPLORE

New Orleans to Memphis

9 Day Itinerary aboard American Countess
  • Discover St. Francisville
  • Experience the music of Memphis
  • Learn the history of Vicksburg
  • Explore vibrant New Orleans
Starts/ Ends in:
New Orleans / Memphis
Activities:
Archaeological Site Visits, River Cruises
Activity Level:
Relaxed
The Lower Mississippi River has stories to share – a legacy that flows from Memphis to the Gulf of Mexico. Embark on more than just a cruise, and return with more than memories: experience, understanding, an enlightened perspective. Explore the American South and discover all the great sights …
Cruise Details
0
View the iconic arch when you visit St. Louis, gateway to the west
$5,999
EXPLORE

Minneapolis to New Orleans

16 Day Itinerary aboard American Countess
  • Explore the arts in Minneapolis, MN
  • Discover St. Louis, Missouri
  • Enjoy musical history in Memphis
  • Learn about Civil War history
  • Admire the diversity of New Orleans
Starts/ Ends in:
Minneapolis / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
As you sail the Mississippi River from Minneapolis to New Orleans aboard the American Countess, observe how landscapes, cultures, and even language change. Sail nearly the whole length of the mighty Mississippi on this 16-day voyage. Visit ancient port cities and sleepy small towns along the way to …
Cruise Details
0
St. Louis' iconic arch at night
$2,699
Save 50%
EXPLORE

St. Louis to Minneapolis

9 Day Itinerary aboard American Queen
  • Explore the culture of St. Louis
  • See Mark Twain's hometown, Hannibal
  • Relax in laid-back La Crosse
  • Admire local artwork in Red Wing
Starts/ Ends in:
St. Louis / Red Wing
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Explore the land and river that inspired legendary American author Samuel Clemens, better known by his pen name, Mark Twain. Cruise northward from St. Louis, Missouri along the mighty Mississippi River, toward the city of Minneapolis. Along the way, explore port towns such as Hannibal, Missouri, …
Cruise Details
0
Visit historic St. Louis
$2,899
EXPLORE

Minneapolis to St. Louis

9 Day Itinerary aboard American Duchess
  • Explore the culture of St. Louis
  • See Mark Twain's hometown, Hannibal
  • Relax in laid-back La Crosse
  • Admire local artwork in Red Wing
Starts/ Ends in:
St. Louis / Red Wing
Activities:
Archaeological Site Visits, River Cruises, Village Visits
Activity Level:
Relaxed
Discover the region and river that inspired renowned American novelist Samuel Clemens, better known as Mark Twain. Sail north from Minneapolis on this 9-day voyage aboard American Countess along the gorgeous Mississippi River toward the city of St. Louis. Along the way, stop in port towns such as …
Cruise Details
0
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