Have questions? We're here.

Top Mississippi River Tours & Cruises in 2025

Travel made your way
New Orleans
Sean Pavone
Visit the famed Bourbon Street
St Louis
Sean Pavone
View the iconic arch when you visit St. Louis, gateway to the west
Vicksburg
Michael Warren
View a Civil War battlefields in Mississippi
Talk with an expert
Build your ideal Mississippi River trip. Call 1.406.541.2677
Start Planning My Trip
Discover Mississippi River in 2025 on one of these trips hand selected by the travel experts at Adventure Life. Select any of the below 4 top-rated trips where you will explore New Orleans, Baton Rouge, Natchez, Vicksburg, and Red Wing with an exceptional bilingual guide on a small group or customizable private tour. The most popular things to do in Mississippi River in are river cruises, cruises, cultural, archaeological site visits, and village visits. Our Mississippi River trips in 2025 range in price from $3,999 to $30,999 for trips of 8 to 15 days. Contact one of Adventure Life's expert Mississippi River trip planners for help planning a seamless experience.
Filter (4 Results)
  • Start Date
    OR, More specific start
  • Length
    to
  • Price
    to
  • Activity Level
  • Experiences
  • Activities
  • Ship
  • Destinations
    • Mississippi River
View the iconic arch when you visit St. Louis, gateway to the west
$12,999
EXPLORE

America’s Great River

St. Paul to New Orleans - 15 Day Itinerary aboard Viking Mississippi
  • Explore St. Louis' arts scene
  • Enjoy American music styles
  • Learn Civil War history
  • Experience New Orleans' culture
  • Visit the Quad Cities
Starts / Ends:
St. Paul / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Village Visits
Activity Level:
Relaxed
Discover the history, natural beauty, and distinctive regional cultures of America's great river, the mighty Mississippi, on this 15-day cruise aboard Viking Mississippi. Set sail from St. Paul, Minnesota, and venture south toward New Orleans, Louisiana. Along the way, visit small towns and …
Cruise Details
0
Visit historic Memphis, Tennessee
$5,499
EXPLORE

Heart of the Delta

New Orleans to Memphis - 12 Day Itinerary aboard Viking Mississippi
  • Enjoy the music of Memphis
  • Get a taste of Cajun cuisine
  • Discover Civil War history
  • See the historic homes of Natchez
Starts / Ends:
New Orleans / Memphis
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
Immerse yourself in the history and heritage of the Mississippi River on this 12-day voyage from New Orleans to Memphis. Soak up the rich French and Acadian cultures that infuse the Lower Mississippi, and be inspired by the stories of famed musicians and Civil Rights heroes. Savor delicious Cajun …
Cruise Details
0
Wander through the historic French Quarter
$3,999
EXPLORE

New Orleans & Southern Charms

8 Day Itinerary aboard Viking Mississippi
  • Enjoy Cajun and Creole cuisine
  • Indulge in New Orleans' music
  • Learn the history of Vicksburg
  • See the historic homes of Natchez
Starts / Ends:
New Orleans / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Urban Exploration, Village Visits
Activity Level:
Relaxed
The Lower Mississippi overflows with charm, history and hospitality. Wander historic estates, and visit notable Civil War sites. Explore the bustling French-influenced port cities of New Orleans and Baton Rouge. Sway to the tempos of Dixieland jazz, gospel and blues. Savor gourmet Cajun and Creole …
Cruise Details
0
The upper Mississippi region
$6,999
EXPLORE

America’s Heartland

St. Louis to St. Paul - 12 Day Itinerary aboard Viking Mississippi
  • Discover history of the Mississippi
  • Explore Dubuque, Iowa
  • Experience Mississippi river towns
  • Admire local artisan work
Starts / Ends:
St. Louis / St. Paul
Activities:
Archaeological Site Visits, River Cruises, Village Visits
Activity Level:
Relaxed
On this enlightening journey on the Upper Mississippi, hear stories of pioneers and the Lewis and Clark Expedition; walk in the footsteps of Mark Twain; and learn about the Norwegian migration. Enjoy the view as your ship navigates through the river’s intricate lock system. Experience the …
Cruise Details
0
1-4 of 4 Results

Top Mississippi River Travel Destinations

Mississippi River Trips by Departure Date

Top Experiences in Mississippi River

Mississippi River Trips by Activity

More Reasons

Why Travel With Adventure Life

All News

Recognized By