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Ruins in Colon, Panama

Best Small Ship Cruises to Colon

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Discover the best small ship cruises to Colon—a more personal, crowd-free way to explore stunning coastlines and hidden ports that big ships can't reach. At Adventure Life, we work with top-rated cruise lines visiting places like , and we’ll help match you with the perfect ship and itinerary based on what you love. These cruises start at $323 for trips lasting 5 to 11 days in 2025. Tell us about your dream Colon cruise, and our travel experts will help make it a reality.
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    • Colon
Transitioning the Panama Canal
from $323
EXPLORE

Panama Canal Full Transit

1 Day Itinerary
  • See the Panama City skyline
  • Learn the history of the canal
Activity Level
Relaxed
This Panama City one-day tour takes you on the incredible journey from the Atlantic Ocean all the way to the Pacific Ocean, traversing two impressive locks via the manmade wonder that is the Panama Canal.
Tour Details
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Panama Canal
from $7,461
EXPLORE

Costa Rica and the Panama Canal

Eastbound - 8 Day Itinerary aboard National Geographic Quest
  • Observe animals in their habitat
  • Kayak through magical mangroves
  • Transit the historical Panama Canal
  • Explore Gulf of Panama beaches
Activities
Land & Sea Exploration, Hiking, Kayaking, Horseback Riding, Stand Up Paddle Boarding
Activity Level
Variable
Discover Costa Rica & Panama on this wonderful 8-day expedition cruise aboard the National Geographic Quest. Venture into remote wilderness and hike among monkeys, sloths, and tropical birds, explore idyllic islands, snorkel over a vibrant coral reef, and take an expedition landing craft cruise through mangroves.
Cruise Details
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Explore beautiful Costa Rica
from $6,420
Bonus
EXPLORE

Panama and Costa Rica by Sea: The Natural Wonders of Central America – with Smithsonian Journeys

Colon - Puntarenas - 8 Day Itinerary aboard Le Champlain
  • Discover San Blas
  • Experience Panama Canal
  • Explore Fuerte Amador
  • Visit Darien National Park
Starts / Ends
Colon / Puntarenas
Activities
Snorkeling, Wildlife Viewing
Activity Level
Variable
Join this 8-day cruise aboard Le Champlain to explore the natural wonders and cultural heritage of Panama and Costa Rica, including the white sands of Holandes Cayes, the iconic Panama Canal, and Panama City's historic Old Quarter.
Cruise Details
0
from $9,230
EXPLORE

Secrets of Central America

Colón - Puntarenas - 11 Day Itinerary aboard Le Champlain
  • Discover National Parks
  • Sail through the Panama Canal
  • Encounter with Emberas tribe
  • Visit San Blas archipelago
Starts / Ends
Colon / Puntarenas
Activities
Village Visits, Archaeological Site Visits
Activity Level
Variable
Join this 11-day Secrets of Central America cruise and explore Panama and Costa Rica, starting at San Lorenzo’s Fort and traveling from the Atlantic to the Pacific. Visit the San Blas Islands, the Pearl Islands, Darien National Park, and cross the Panama Canal. Meet local communities, and discover the biodiversity of Rio Esquinas and Curú Nature Reserve.
Cruise Details
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