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Panama City Small Ship Cruises

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Experience the wonders of Panama and Costa Rica on an extraordinary journey with Adventure Life's small ship cruises for 2026. From cruising among the Gulf of Panama to exploring Manuel Antonio National Park and the Curú National Refuge, this 8-day voyage aboard the Safari Voyager offers an unforgettable adventure. Delve into lush jungles, mangroves, national parks, and the iconic Panama Canal while searching for untamed wildlife and enjoying activities like kayaking, snorkeling, and wildlife viewing. Immerse yourself in the natural beauty and rich biodiversity of Central America on this relaxing expedition. Don't miss the chance to explore these stunning destinations - contact one of Adventure Life's tour specialists for help planning your next seamless trip.
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    • Panama City
Guests explore by zodiac cruise in Portobelo, Panama
from $6,150
EXPLORE

The Panama Canal, Pearl Islands and Darien Jungle

Southbound - 8 Day Itinerary aboard National Geographic Quest
  • Transit the Panama Canal
  • Explore Darien Jungle
  • Visit Portobelo Forts
  • Snorkel Pearl Islands
Starts / Ends
Panama City / Balboa
Activities
Hiking, Snorkeling, Wildlife Viewing, Kayaking, Stand Up Paddle Boarding, Village Visits, Urban Exploration
Activity Level
Variable
Embark on an 8-day Panama Canal cruise to the Pearl Islands and Darien Jungle aboard the National Geographic Quest. Transit the legendary Panama Canal, meet the Emberá people in Playa Muerto, spot wildlife in Punta Patiño, and snorkel the clear waters of the Pearl Islands, including Isla del Rey and Isla Pacheca.
Cruise Details
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Panama Canal
from $6,320
Save 20%
EXPLORE

Costa Rica and the Panama Canal

Eastbound - 8 Day Itinerary aboard National Geographic Quest
  • Observe animals in their habitat
  • Kayak through magical mangroves
  • Transit the historical Panama Canal
  • Explore Gulf of Panama beaches
Activities
Land & Sea Exploration, Horseback Riding
Activity Level
Variable
Discover Costa Rica & Panama on this wonderful 8-day expedition cruise aboard the National Geographic Quest. Venture into remote wilderness and hike among monkeys, sloths, and tropical birds, explore idyllic islands, snorkel over a vibrant coral reef, and take an expedition landing craft cruise through mangroves.
Cruise Details
0
Paradise Tropical Island - Bocas del Toro archipelago - Island Colon
from $24,990
OBC
EXPLORE

Pristine Islands of the Bahamas & the Panama Canal

Nassau - Panama City - 11 Day Itinerary aboard Scenic Eclipse
  • Explore Nassau’s colonial streets
  • Visit Staniel Cay’s beaches
  • Discover San Salvador’s coral reefs
  • Meet Cabo de La Vela’s Wayuu people
Starts / Ends
Nassau / Panama City
Activity Level
Variable
Join an 11-day cruise from Nassau to Panama City on the Scenic Eclipse, exploring the Bahamas' clear waters and vibrant island cultures. Experience highlights like Pig Beach and the Panama Canal, blending leisure with cultural discovery.
Cruise Details
0
Sunset over Cartagena, Colombia
from $6,450
Save 20%
EXPLORE

Panama and Colombia: Exploring the Caribbean Coast

Panama to Cartagena - 8 Day Itinerary aboard National Geographic Quest
  • Transit the Panama Canal
  • Meet Indigenous people of Guna Yala
  • Look for unique tropical wildlife
  • See colonial architecture
Starts / Ends
Panama City / Cartagena
Activities
Archaeological Site Visits
Activity Level
Variable
Discover an astonishing trove of natural and cultural treasures as you navigate the Caribbean coasts of Panama and Colombia on this 8-day cruise aboard the National Geographic Quest. Sail from Panama City to Cartagena, with stops in Portobelo, Guna Yala, Archipelago, and more.
Cruise Details
0
Panama Canal
from $12,795
EBD
EXPLORE

Costa Rica and The Panama Canal

San Jose - Panama - 12 Day Itinerary aboard Sylvia Earle
  • Cross Panama Canal
  • Explore biodiverse rainforests
  • Visit Coiba National Park
  • Enjoy Manuel Antonio National Park
Starts / Ends
San Jose / Panama City
Activities
Rainforest Exploration
Activity Level
Variable
Embark on a 12-day cruise aboard the Sylvia Earle to explore Central America's rich ecosystems, from Costa Rica's diverse wildlife to Panama's vibrant coral reefs. Experience a memorable daylight transit through the historic Panama Canal, witnessing this engineering marvel firsthand.
Cruise Details
0
Transitioning the Panama Canal
from $323
EXPLORE

Panama Canal Full Transit

1 Day Itinerary
  • See the Panama City skyline
  • Learn the history of the canal
Activity Level
Relaxed
This Panama City one-day tour takes you on the incredible journey from the Atlantic Ocean all the way to the Pacific Ocean, traversing two impressive locks via the manmade wonder that is the Panama Canal.
Tour Details
0
View of the Miraflores Locks
from $276
EXPLORE

Panama Canal Partial Transit

½ Day Itinerary
  • Transit through Miraflores Locks
  • Learn the history of the canal
Activity Level
Relaxed
Climb aboard and experience the "Eighth Wonder of the World" first hand as you transit through the Miraflores Locks to the Pacific Ocean.
Tour Details
0
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