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Top South America Trips & Tours in April 2026

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Llamas in Machu Picchu, Peru
from $3,060
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Classic Salkantay Trek

Via Hidroelectrica - 9 Day Itinerary
  • Travel the Salkantay Trail
  • Visit local communities
  • Explore Machu Picchu
Starts / Ends
Cusco / Cusco
Activities
Camping, Archaeological Site Visits
Activity Level
Challenging
This tour is a great alternative to the popular Inca Trail if you want to experience a different route that ends at Machu Picchu. Enjoy the magnificent view of Mount Salkantay and head towards the mystical Lost City of Incas.Trek through the less traveled route of the Salkantay trail and tour the ruins of Machu Picchu.
Tour Details
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Cruise the Galapagos on the Legend ship
from $118,008
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Private Charter - Central & East Islands Aboard Galapagos Legend

4 Day Itinerary aboard Galapagos Legend
  • Snorkel in crystal clear waters
  • Tour the tortoise breeding center
  • Enjoy on board family activities
Starts / Ends
Baltra / San Cristobal Airport
Activity Level
Variable
Board the Galapagos Legend for a unique 4-day private cruise exploring the central and eastern islands of the Galapagos archipelago. Get ready to snorkel, hike and encounter wildlife such as sea lions, marine iguanas, and giant tortoises many which are unique to the Galapagos, found nowhere else in this world
Cruise Details
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Corals during the sunset
from $45,787
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Private Charter - Galapagos Central Islands Aboard Corals

4 Day Itinerary aboard Corals
  • Visit the Charles Darwin Station
  • Explore Dragon Hill's wildlife
  • Snorkel & swim at Bartolome Island
Starts / Ends
Baltra / Baltra
Activity Level
Variable
During this 4-day private cruise explore the North Central islands of the Galapagos and visit the Fausto Llerena Breeding Center, home to the Galapagos giant tortoise and where the famous Lonesome George used to live. Walk through trails escorted by endemic land iguanas, mockingbirds, and Darwin´s finches, snorkel in crystalline waters and more!
Cruise Details
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Coral I
from $45,787
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Private Charter - Galapagos Northeast Islands Aboard Corals

4 Day Itinerary aboard Corals
  • Explore the Charles Darwin Station
  • Visit Mosquera Islet´s sea lions
  • Walk in South Plaza´s cactus forest
Starts / Ends
Baltra / San Cristobal Airport
Activities
Whale Watching
Activity Level
Variable
Delight yourself with close encounters with the Galapagos tortoises, sea lions, sharks, and blue-footed boobies during this 4-day private cruise across the northeast islands of the Galapagos and experience the best of the archipelago, visiting a variety of locations such as the Charles Darwin Station, Mosquera Islet, North Seymour, San Cristobal, and more!
Cruise Details
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Mompox, Colombia
from $4,149
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Magic of Colombia - Cruise Only

Barranquilla - Cartagena - 8 Day Itinerary aboard MS AmaMagdalena
  • Experience Barranquilla’s Carnaval
  • Explore Sitio Nuevo’s village life
  • Discover Boca de Tacaloa landscapes
  • Stroll Mompox’s colonial streets
Starts / Ends
Cartagena / Cartagena
Activity Level
Variable
Embark on an 8-day cruise along Colombia's Magdalena River from Barranquilla to Cartagena on the AmaMagdalena. Enjoy vibrant music, local coffee, unique wildlife, and authentic cultural experiences, including a private Carnaval celebration.
Cruise Details
0
(Seymour) Sea Lions in and out of the H2O
from $2,395
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Southern Islands I

4 Day Itinerary aboard Archipel I
  • Visit wildlife observation points
  • Observe a colony of sea lions
  • Meet the Galapagos giant turtles
Starts / Ends
San Cristobal Airport / Baltra
Activity Level
Variable
Enjoy this 4-day cruse through the southern islands of the Galapagos on the Archipel I. Get the opportunity to explore the wildlife-rich shores and breathtaking landscapes of San Cristobal, South Plaza, Santa Fe, Floreana, and Santa Cruz.
Cruise Details
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Cartagena Old Town
from $4,049
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Wonders of Colombia

Cartagena - Barranquilla - 8 Day Itinerary aboard MS AmaMelodia
  • Explore ancient ruins and markets
  • Visit Bocas de Cenizas and museum
  • Enjoy Columbian nature and wildlife
Starts / Ends
Cartagena / Cartagena
Activities
Village Visits, Wildlife Viewing, Festival Visits
Activity Level
Variable
Discover Colombia's wonders on an 8-day cruise along the Magdalena River aboard AmaMelodia. Visit Palenque, the first free city, and the vibrant Getsemaní neighborhood in Cartagena. Discover the blend of cultures, music, and art that define the country.
Cruise Details
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Wooden boardwalk in Bartolome
from $4,150
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Central Islands

5 Day Itinerary aboard Treasure of Galapagos
  • Visit The Interpretation Center
  • Observe avian courtship rituals
  • Interact with gentle giant tortoise
Starts / Ends
Baltra / San Cristobal Airport
Activity Level
Variable
This 5-day voyage on the Treasure of the Galapagos explores the central islands of the Galapagos, including Santa Cruz, Bartolome, North Seymour, Mosquera, South Plaza, and San Cristobal. Experience the picturesque landscape, unique wildlife, and snorkeling opportunities offered by this exciting Galapagos tour.
Cruise Details
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View the abundant wildlife of the Amazon
from $3,743
up 30% off
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Amazon Discovery

5 Day Itinerary aboard M/V Anakonda
  • Learn about the Amazon's diversity
  • Visit an Authentic Indigenous home
  • Navigate pristine water sections
Starts / Ends
Coca / Yasuni National Park
Activity Level
Variable
Embark on an Amazon River cruise aboard the M/V Anakonda. This luxury small-ship vessel takes you to the heart of the Ecuadorian Amazon to see the pink river dolphin, black caiman, and anaconda in their natural habitat. Keep an eye out for crocodiles, monkeys, and hoatzins in the river.
Cruise Details
0
Pink dolphin
from $4,650
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Voyage to the Heart of the Amazon

Roundtrip Manaus - 7 Day Itinerary aboard Tucano
  • Enjoy daily walks and swimming time
  • Observe magnificent plants
  • Listen for bird and mammal calls
  • Look for caimans in the river
Starts / Ends
Manaus / Manaus
Activities
Fishing
Activity Level
Variable
Experience a 7-day Amazon River cruise on the M/Y Tucano, starting from Manaus and exploring the Rio Negro's untouched ecosystems. Engage in daily excursions, including rainforest walks while discovering diverse wildlife and learning from expert naturalists.
Cruise Details
0
Capybaras in the water
from $3,320
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Amazon Wildlife & Culture Journey

Nauta Roundtrip - 7 Day Itinerary aboard Amatista
  • See pink and grey dolphins play
  • Meet and visit with locals
  • Admire the Amazon wildlife
  • Visit the birth place of the Amazon
Starts / Ends
Iquitos / Nauta
Activities
Rainforest Exploration, Kayaking
Activity Level
Variable
This week-long river cruise onboard Amatista is ideal for flora and fauna enthusiasts who want to experience the Amazon rainforest. This region of the world is a birding enthusiast's paradise. Also, witness pink river dolphins in a way you've never seen them before.
Cruise Details
0
Treasure of the Galapagos
from $66,400
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Private Charter - Central Islands Aboard Treasure of Galapagos

5 Day Itinerary aboard Treasure of Galapagos
  • Interact with gentle giant tortoise
  • Observe avian courtship rituals
  • Visit The Interpretation Center
Starts / Ends
Baltra / San Cristobal Airport
Activities
Hiking, Snorkeling
Activity Level
Variable
This 5-day private voyage on the Treasure of the Galapagos explores the Central Islands of the Galapagos, including Santa Cruz, Bartolome, North Seymour, Mosquera, South Plaza, and San Cristobal. Experience the volcanic landscape, unique wildlife, and snorkeling opportunities offered by this exciting Galapagos tour.
Cruise Details
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A lovely reflection off the Amazon River
from $5,000
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Luxury Amazon Explorer - High Water

Roundtrip Nauta - 5 Day Itinerary aboard Aria Amazon
  • Explore the Ucayali River
  • Navigate the Zapote River
  • Tour Nauta’s local market
  • Explore the Yarapa River by skiff
Starts / Ends
Iquitos / Nauta
Activity Level
Variable
Embark on a 5-day cruise through the Peruvian Amazon aboard the Aria Amazon, starting with a city tour in Iquitos. Experience the rich biodiversity with river excursions, rainforest hikes, and opportunities to engage with local communities, ending with a visit to the Manatee Rescue Center in Nauta.
Cruise Details
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Grapes at a vineyard
from $1,328
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Mendoza

4 Day Itinerary
  • Attend an Argentine cooking class
  • Tour a Mendoza winery
  • Horseback & hiking options
Activities
Horseback Riding
Activity Level
Relaxed
Visit this region's important vineyards and compliment your wine tasting with an exclusive cooking class on our 4 day Mendoza tour. Round out your time here with a horseback ride or a trek to the Quebrada del Salta water falls.
Tour Details
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Sunset over Cartagena, Colombia
from $2,005
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Cartagena Adventure

5 Day Itinerary
  • Visit Cartagena's historical sites
  • Prepare dishes with a local chef
  • Taste the best liquor in Colombia
  • Visit the Bazurto market
  • Swim in Tierra Bomba
  • Learn about Palenque de San Basilio
Starts / Ends
Cartagena / Cartagena
Activities
Wine Tasting, Cooking Classes, Local Market Visits
Activity Level
Easy Active
Experience Cartagena’s vibrant culture with rum and chocolate tasting, a market tour and cooking class, a historical visit to San Basilio de Palenque, and a relaxing day at Blue Apple Beach. This unique trip delves into the heart of Colombia’s rich heritage and stunning landscapes.
Tour Details
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Cathedral
from $364
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Explore Cuenca

4 Day Itinerary
Activities
Urban Exploration
Activity Level
Relaxed
Fly south to the delightful city of Cuenca. Considered the most colonial city in all the Americas, red clay rooftops stretch throughout the city and baroque churches seem to stand on every corner. This time in Cuenca is yours to explore however you like. Chose from several short excursions to add to your stay in this charming town.
Tour Details
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Enjoy a blissful snorkeling trip.
from $6,195
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Western Islands

7 Day Itinerary aboard Treasure of Galapagos
  • Hike Dragon Hill on Santa Cruz
  • Appreciate Isabela's wetlands
  • Observe diverse wildlife
  • Snorkel, swim & hike the Galapagos
Starts / Ends
Baltra / Baltra
Activity Level
Variable
This 7-day Western Islands cruise on the ship, Treasure of the Galapagos, explores Rabida, Santa Cruz, Fernadina, and more! Experience the fascinating western islands and understand how volcanic activity and isolation shaped the landscape. Encounter diverse wildlife, birdlife, and marinelife on your memorable vacation.
Cruise Details
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Hiking in Ecuador
from $1,722
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Cotopaxi Trekking

7 Day Itinerary
  • Take in the volcanic mountain views
  • Hike through native Andean forest
  • Visit an Andean Cowboy community
  • Explore Inca sites
Activities
Hacienda Visits
Activity Level
Challenging
Experience Cotopaxi National Park in a unique way as you trek the ancient roads of the Inca. The full day hikes will take you past Inca sites and offer stunning views of Cotopaxi volcano. During your five days of hiking you'll split your evenings between campsites and classic Haciendas.
Tour Details
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