Have questions? We're here.
What a view.

Top South America Trips & Tours in May 2026

Travel made your way
Talk with an expert
Build your ideal South America trip. Call 1.406.541.2677
Start Planning My Trip
Filter (716 Results)
  • Start Date
    OR, More specific start
  • Length
    to
  • Price
    to
  • Activity Levels
  • Experiences
  • Activities
  • Ships
  • Destinations
    • South America
Red scarlet macaw in flight
from $2,868
EXPLORE

Rio de Janeiro and Amazon Clipper Cruise

8 Day Itinerary
  • Enjoy views of Rio de Janeiro
  • Visit Christ the Redeemer
  • Learn about local flora and fauna
  • Canoe along the Rio Negro
Starts / Ends
Rio de Janeiro / Manaus
Activities
Snorkeling, Land & Sea Exploration, Urban Exploration
Activity Level
Relaxed
During your visit to Rio de Janerio, visit the mountaintops of Corcovado and Sugarloaf, two of Rio's iconic peaks, and stroll the beaches of Ipanema and Copacabana. Fly to Manaus, the entrance of the Brazilian Amazon, and embark the Amazon Clipper for a 4-day cruise along the wildlife rich waters of the Rio Negro, one of the Amazon River's largest tributaries.
Tour Details
0
Uacari Lodge
from $2,532
EXPLORE

Uakari Floating Lodge

5 Day Itinerary
  • Explore the beauty of the Amazon
  • Visit local communities
  • Look for unique Amazonian wildlife
Starts / Ends
Uakari Floating Lodge / Uakari Floating Lodge
Activities
Wilderness Lodge Exploration
Activity Level
Relaxed
Explore the Amazon on this 5-day tour from the comfort of the community-run Uakari Floating Lodge. Located in the Mamirauá Sustainable Developments Reserve, this floating lodge offers a full-service experience. Spend your time hiking or canoeing through the forest learning about the local habitat and looking out for unique animals with your guide.
Tour Details
0
Explore the exotic plant life in Alerce Adino National Park
from $1,745
EXPLORE

Chilean Lake District

5 Day Itinerary
  • Hike Alerce Andino National Park
  • Hike to Petrohue Waterfall
  • Explore Puerto Varas
  • B&B on Lake Todos los Santos
Activity Level
Relaxed
Explore the pristine lakes, rivers, and volcanoes that make up the Chilean Lake District on our 5 day tour. Nature hikes, wildlife viewing, kayaking, and fly fishing are activities that will ensure you experience all aspects of the Chilean Lake District!
Tour Details
0
Whale watching on Peninsula Valdes
from $600
EXPLORE

Peninsula Valdes Self-Drive

4 Day Itinerary
Activities
Whale Watching
Activity Level
Relaxed
Tour Details
0
Pink Dolphins swimming in the Amazon River
from $6,700
EXPLORE

Amazon Encounter - High Water Season

Nauta - Iquitos - 5 Day Itinerary aboard Delfin Amazon Cruises
  • See vibrant Amazon wildlife
  • Encounter pink dolphins
  • Visit Fundo Casual
  • Learn bee project
Starts / Ends
Iquitos / Iquitos
Activity Level
Variable
Set sail on a 5-day Amazon River cruise aboard the Delfin I. Depart from Iquitos and journey through Nauta, Yanayacu, Yarapa, and the Amazon Confluence. Explore wildlife, paddle rivers, meet local communities, and learn rainforest traditions. Enjoy skiff rides, night safaris, and close encounters with pink river dolphins.
Cruise Details
0
Black Turtle cove with mangroves
from $4,600
Savings
EXPLORE

Northern Islands

5 Day Itinerary aboard Alya
  • Swim and snorkel at Darwin Bay
  • Discover Genovesa Island's birdlife
  • Hike to Dragon Hill
Starts / Ends
Baltra / Charles Darwin Center
Activities
Stand Up Paddle Boarding
Activity Level
Variable
Sail to one of the most unique archipelagos in the world on this 5-day Galapagos Islands cruise aboard the Alya catamaran. The Galapagos Islands are teeming with sea life including blue-footed boobies, giant tortoises, land and marine iguanas, sea lions, and penguins.
Cruise Details
0
At the Parrot Clay Lick
from $4,069
EXPLORE

Manu Explorer

8 Day Itinerary
  • See giant otters in oxbow lakes
  • Visit Macaw Clay Lick Project
  • Fall asleep to the forest sounds
  • Enjoy the changing scenery
Activity Level
Relaxed
Experience Manu National Park, the most biologically diverse place on the planet, like virtually no one else can: camp inside the park at the Manu Wildlife Tent Camp. Delight in the sights and sounds of this 1.8 million-hectare jungle paradise.
Tour Details
0
Atacama Moon
from $3,730
EXPLORE

Atacama Desert Trek

Private Tour - 7 Day Itinerary
  • Hike Valle de la Luna’s dunes
  • Visit stripped hills Rainbow Valley
  • View ancient petroglyphs at Yerbas
  • Trek to Rio Grande through trails
Starts / Ends
Atacama Desert / Atacama Desert
Activity Level
Challenging
Explore the Atacama Desert on a 7-day trekking tour through Chile’s most iconic landscapes. Hike Valle de la Luna, Rainbow Valley, and Guatin Valley. Visit ancient petroglyphs, the village of Rio Grande, the Tatio Geysers, and the Atacama Salt Flat. See flamingos at the turquoise Miscanti and Miñiques Lagoons before returning to Calama.
Tour Details
0
Keep an eye to the rainforest canopy for an array of wildlife in Madidi National Park in Bolivia
from $1,331
EXPLORE

Madidi Jungle Ecolodge

Bolivian Amazon - 6 Day Itinerary
  • Search for Bolivian wildlife
  • Enjoys views Madidi National Park
  • Learn about traditional customs
  • Explore the town of Rurrenabaque
Starts / Ends
La Paz / La Paz
Activity Level
Easy Active
This 6-day tour of Bolivia's Amazon takes you to Madidi National Park, where you'll stay 3 nights in Madidi Jungle Ecolodge - Owned and operated by an indigenous community in Bolivia. Here, learn to see the jungle through the eyes of the local Quechua Indians as you explore and look for wildlife and learn about traditional farming & cuisine.
Tour Details
0
Trek the Route of the Parks of Patagonia
from $5,357
EXPLORE

Rincon Bonito: Patagonia's Hidden North

10 Day Itinerary
  • Rafting adventure on Petrohue River
  • Cochamo Valley Exploration
  • Paddling in Reloncaví Fjord
  • Trek the North Patagonian Andes
Starts / Ends
Puerto Montt / Puerto Varas
Activities
Village Visits, Hiking, Whitewater Rafting
Activity Level
Moderate
On the 10-day Rincon Bonito: Patagonia's Hidden North tour, explore Puerto Varas and the Chilean Patagonia Lake District. Highlights include a walking tour along Lake Llanquihue, rafting on the Petrohue River, a visit to Cochamo Valley, and a paddling adventure in the Reloncavi Fjord. Conclude the trip with a trek through the North Patagonian Andes.
Tour Details
0
Beautiful Galapagos landscape
from $10,000
EXPLORE

Islands Circumnavigation

15 Day Itinerary aboard Samba
  • See sea lions on Mosquera
  • Explore in the Mangrove forest
  • Enjoy a volcanic Olivine beach
  • Take incredible photos of landscape
Activities
Small Ship Sailing
Activity Level
Variable
Enjoy 15 days of relaxing and fun aboard Samba yacht! Visit Santa Cruz, Floreana, Española, San Cristobal, Santa Fe, Santiago, Bartholomew, Rabida and North Seymour. Discover the magnificent wildlife and the incredible landscapes on Galapagos Islands .
Cruise Details
0
Don\'t get too close
from $4,050
EXPLORE

Guyana Rainforest

6 Day Itinerary
  • Tour Georgetown’s historic markets
  • Paddle the Burro Burro River
  • Hike Surama Mountain trails
  • Visit majestic Kaieteur Falls
Activity Level
Relaxed
This 6-day tour explores remote Guyana, with birdwatching on Surama Mountain, a visit to the Amerindian village of Surama, and paddling the Burro Burro River. Spot wildlife, including spider monkeys, river otters, and tapirs, and end at Kaieteur Falls, five times the height of Niagara Falls.
Tour Details
0
Enjoying the landscape of Lencois Maranhenses National Park
from $1,849
EXPLORE

Lençóis Maranhenses Trekking

6 Day Itinerary
  • Trek through dunes & lagoons
  • Swim in clear freshwater pools
  • Explore the town of Baixa Grande
  • Walk the charming streets of Atins
Activities
Camping
Activity Level
Moderate
Begin your 6-day Brazil trek in Sao Luis de Maranhao, a UNESCO World Heritage Site known for its magnificent colonial architecture. For the next few days hike, swim, and explore your way through Brazil's white sand dunes on this expedition tour of Lenois Maranhenses National Park. You'll also visit the small town of Baixa Grande and the Rio Negro.
Tour Details
0
The Amazon River
from $11,340
NO SS
EXPLORE

Luxury Amazon Expeditions Cruise - High Water

Roundtrip Iquitos - 8 Day Itinerary aboard Aqua Nera
  • Discover Iquitos cuisine
  • Spot Yanayacu Yacapana wildlife
  • Learn about Amazon fierce piranhas
  • Visit Clavero Lake villagers
Starts / Ends
Iquitos / Iquitos
Activities
Local Market Visits
Activity Level
Variable
Embark on an 8-day Amazon River cruise on the Aqua Nera, starting with a warm welcome and local cuisine in Iquitos. Explore rivers, wildlife, artisan markets, and conservation efforts, concluding your journey with a visit to the Manatee Rescue Center.
Cruise Details
0
A pair of friendly sea lions
from $9,445
Savings
EXPLORE

Island Circumnavigation

8 Day Itinerary aboard Galapagos Horizon
  • Discover Sullivan Bay's beauty
  • Observe mola-mola sunfish
  • Swim & snorel across Isabela Island
  • Visit South Plaza Islands
Starts / Ends
Baltra / San Cristobal Airport
Activity Level
Variable
This 8-day cruise offers incredible snorkeling, hiking, and kayaking adventures all around the Galapagos archipelago in style. Gourmet cuisine, the best guides, and spacious & stylish cabins guarantee a top-notch luxury cruising experience second to none.
Cruise Details
0
baby sloth... oh so soft
from $5,600
EXPLORE

Amazon Encounter - High Water Season

Nauta - Iquitos - 5 Day Itinerary aboard Delfin III
  • Marañón River skiff exploration
  • Dorado River kayak experience
  • Amazon tributary confluence views
  • Fundo Casual rainforest walk
  • Pacaya River full exploration
Starts / Ends
Iquitos / Iquitos
Activities
Rainforest Exploration, Wildlife Viewing, Kayaking, Fishing
Activity Level
Variable
Embark on a 5-day Peruvian Amazon cruise from Iquitos to Nauta aboard the Delfin III. Cruise rivers, spot wildlife, kayak flooded forests, and visit riverside communities inside Pacaya Samiria National Reserve. Experience guided excursions, cultural insights, and unique rainforest ecosystems.
Cruise Details
0
Kayaking Tagus Cove
from $5,000
EXPLORE

Northwest Islands

8 Day Itinerary aboard Samba
  • See sea lions on Mosquera
  • Observe the nesting of boobies
  • Explore in the Mangrove forest
  • Hiking and observe the twin craters
Starts / Ends
Baltra / Baltra
Activity Level
Variable
Explore 8 days of relaxing and fun aboard Samba yacht! Visit Genovesa, Isabela, Marchena, Fernandina, Floreana, Santa Cruz. Discover wildlife and the incredible landscapes of the Galapagos Islands!
Cruise Details
0
Bird perched in the Amazon rainforest
from $1,947
EXPLORE

Amazon Journey

Iquitos to Nauta - 4 Day Itinerary aboard La Perla
  • Visit Pacaya Samiria National Reser
  • Admire the incredible wildlife
  • Learn more about the Amazon culture
Starts / Ends
Iquitos / Nauta
Activity Level
Variable
This 4-day Amazon cruise of Iquitos & Nauta aboard La Perla gives you an insider's view of life in Peru's rainforest, including piranha fishing, wildlife spotting, visit local villages, and opportunities to learn about wildlife preservation!
Cruise Details
0
451-468 of 716 Results

Plan smarter. Spend better.

Talk with an expert trip planner 1.800.344.6118

Plan My Trip
Shannon Fischer-Kendro Adventure Life employee profile
Shannon K.
Peruvian weavers
South America

Chat South America with a specialist

Our team is waiting and ready to talk with you about your next adventure. So go ahead and book an appointment with one of our specialized trip planners.

Let's Chat
1.800.344.6118

Where is your next adventure?

Contact Chat Call
More Reasons

Why Travel With Adventure Life

All News

Recognized By

South America Travel Guide

Favorite South America South America All Trips

Top South America Travel Destinations

South America Trips by Departure Date

Top Experiences in South America

South America Trips by Duration

South America Trips by Activity