Top South America Trips & Tours in November 2026

Embark on an Amazon River cruise aboard the M/V Anakonda. This luxury small-ship vessel takes you to the heart of the Ecuadorian Amazon to see the pink river dolphin, black caiman, and anaconda in their natural habitat. Keep an eye out for crocodiles, monkeys, and hoatzins in the river.

Experience a 7-day Amazon River cruise on the M/Y Tucano, starting from Manaus and exploring the Rio Negro's untouched ecosystems. Engage in daily excursions, including rainforest walks while discovering diverse wildlife and learning from expert naturalists.

This week-long river cruise onboard Amatista is ideal for flora and fauna enthusiasts who want to experience the Amazon rainforest. This region of the world is a birding enthusiast's paradise. Also, witness pink river dolphins in a way you've never seen them before.

Travel aboard Seabourn Pursuit on a 22-day expedition to Antarctica, South Georgia & the Falkland Islands. Start in Buenos Aires, fly to Ushuaia, and explore remote polar regions with expert-led Zodiac landings.

Marvel at vast colonies of penguins, spot majestic whales, look for a variety of species of seals, and watch soaring sea birds. Explore rugged, untouched landscapes, and be humbled by massive icebergs and mountains. The ultimate Southern Ocean experience, this unforgettable 22-day expedition cruise takes you into spectacular wilderness.

This 5-day private voyage on the Treasure of the Galapagos explores the Central Islands of the Galapagos, including Santa Cruz, Bartolome, North Seymour, Mosquera, South Plaza, and San Cristobal. Experience the volcanic landscape, unique wildlife, and snorkeling opportunities offered by this exciting Galapagos tour.

Embark on a 5-day cruise through the Peruvian Amazon aboard the Aria Amazon, starting with a city tour in Iquitos. Experience the rich biodiversity with river excursions, rainforest hikes, and opportunities to engage with local communities, ending with a visit to the Manatee Rescue Center in Nauta.

Explore the Amazon, Ucayali, and Pacaya Rivers on their way deep into the Pacaya Samiria Reserve, one of Peru´s largest national parks. Go piranha fishing, trek into the dense jungle in search of Amazon wildlife and birds, take a night safari and guided trips, visit local villages, and learn about wildlife preservation efforts in Peru’s Amazonia.

Experience Cartagena’s vibrant culture with rum and chocolate tasting, a market tour and cooking class, a historical visit to San Basilio de Palenque, and a relaxing day at Blue Apple Beach. This unique trip delves into the heart of Colombia’s rich heritage and stunning landscapes.

Fly south to the delightful city of Cuenca. Considered the most colonial city in all the Americas, red clay rooftops stretch throughout the city and baroque churches seem to stand on every corner. This time in Cuenca is yours to explore however you like. Chose from several short excursions to add to your stay in this charming town.

This 7-day Western Islands cruise on the ship, Treasure of the Galapagos, explores Rabida, Santa Cruz, Fernadina, and more! Experience the fascinating western islands and understand how volcanic activity and isolation shaped the landscape. Encounter diverse wildlife, birdlife, and marinelife on your memorable vacation.

Experience Cotopaxi National Park in a unique way as you trek the ancient roads of the Inca. The full day hikes will take you past Inca sites and offer stunning views of Cotopaxi volcano. During your five days of hiking you'll split your evenings between campsites and classic Haciendas.