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Top South America Trips & Tours in September 2025

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Enjoying the landscape of Lencois Maranhenses National Park
from $1,646
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Lençóis Maranhenses Trekking

6 Day Itinerary
  • Trek through dunes & lagoons
  • Swim in clear freshwater pools
  • Explore the town of Baixa Grande
  • Walk the charming streets of Atins
Activities
Camping
Activity Level
Moderate
Begin your 6-day Brazil trek in Sao Luis de Maranhao, a UNESCO World Heritage Site known for its magnificent colonial architecture. For the next few days hike, swim, and explore your way through Brazil's white sand dunes on this expedition tour of Lenois Maranhenses National Park. You'll also visit the small town of Baixa Grande and the Rio Negro.
Tour Details
0
from $766
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Choro Trek

3 Day Itinerary
  • Hike in the peaks of the Andes
  • Look for animals along the way
  • Visit pristine waterfalls
Activity Level
Challenging
Extend your trip in Bolivia with the country's most popular trek. The Choro Trek links the high plateau of the Andes with the subtropical lowlands. Hike through a landscape of glaciers and pristine waterfalls on ancient cobbled stone trails built before the Incas.
Tour Details
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Tayrona National Park, Colombia beach retreat
from $6,618
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Colombia Multisport Adventure: Andes to Caribbean

12 Day Itinerary
  • Hike Cane River trail to Ráquira
  • Bike through iconic sites of Bogota
  • Zipline above Juan Curi Falls
  • Explore Tayrona National Park
Starts / Ends
Bogota / Cartagena
Activities
Biking, Archaeological Site Visits
Activity Level
Moderate
Experience Colombia’s rich culture and scenery on this active 12-day trip from Bogotá to the Caribbean coast. Hike to the Lost City, visit colonial towns like Villa de Leyva and Barichara, and unwind in Tayrona National Park’s pristine beaches. Explore Cartagena’s UNESCO-listed charm while connecting with Colombia’s diverse landscapes and heritage.
Tour Details
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Sea lion and scuba diver
from $4,590
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North and West Islands - Diving Itinerary

Santa Cruz to North Seymour - 8 Day Itinerary aboard Danubio Azul
  • Dive at Darwin’s Arch
  • Walk North Seymour trails
  • Discover Cousin’s Rock
  • Snorkel at Vicente Roca Point
Starts / Ends
Baltra / Baltra
Activities
Wildlife Viewing, Snorkeling, Scuba Diving
Activity Level
Variable
Dive into the world-renowned waters of the Galapagos on this 8-day cruise aboard Danubio Azul. This liveaboard expedition explores remote diving sites including Darwin’s Arch, Wolf Island, and Cape Marshall. Discover some of the planet’s richest marine ecosystems on this unforgettable adventure.
Cruise Details
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Beautiful Galapagos landscape
from $10,280
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Islands Circumnavigation

15 Day Itinerary aboard Samba
  • See sea lions on Mosquera
  • Explore in the Mangrove forest
  • Enjoy a volcanic Olivine beach
  • Take incredible photos of landscape
Activity Level
Variable
Enjoy 15 days of relaxing and fun aboard Samba yacht! Visit Santa Cruz, Floreana, Española, San Cristobal, Santa Fe, Santiago, Bartholomew, Rabida and North Seymour. Discover the magnificent wildlife and the incredible landscapes on Galapagos Islands .
Cruise Details
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Vineyard in Uruguay
from $2,803
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Rolling Hills of Pueblo Eden

3 Day Itinerary
  • Explore Maldonado
  • Follow panoramic Route 12
  • Discover the Pueblo Eden region
  • \"Caracoles\" and \"Carape\" Hills
Starts / Ends
Montevideo / Montevideo
Activities
Village Visits, Wine Tasting
Activity Level
Relaxed
On this 3-day extension tour of Uruguay, discover the alpine landscape of northern Maldonado, Uruguay, that once intrigued Charles Darwin. Explore rolling hills, picturesque valleys, and western sunrises. Take the scenic Route 12 for spectacular hill vistas. Uncover the charm of Pueblo Eden and the "Caracoles" and "Carape" Hills on this trip.
Tour Details
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Kayaking Tagus Cove
from $5,140
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Northwest Islands

8 Day Itinerary aboard Samba
  • See sea lions on Mosquera
  • Observe the nesting of boobies
  • Explore in the Mangrove forest
  • Hiking and observe the twin craters
Starts / Ends
Baltra / Baltra
Activity Level
Variable
Explore 8 days of relaxing and fun aboard Samba yacht! Visit Genovesa, Isabela, Marchena, Fernandina, Floreana, Santa Cruz. Discover wildlife and the incredible landscapes of the Galapagos Islands!
Cruise Details
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Uakari Floating Lodge
from $2,089
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Rio de Janeiro and Uakari Amazon Lodge

9 Day Itinerary
  • Enjoy views of Rio de Janeiro
  • Visit Christ the Redeemer
  • Learn about local flora and fauna
  • Canoe through flooded forests
Starts / Ends
Rio de Janeiro / Uakari Floating Lodge
Activities
Urban Exploration, Hiking, Rainforest Exploration
Activity Level
Relaxed
Spend three days in Brazil's iconic Rio de Janerio, where you'll visit Corcovado and Sugarloaf, the two iconic peaks, and stroll the beaches of Ipanema and Copacabana. Spend a day exploring Manaus, the entrance of the Brazilian Amazon, before your 4-day Amazon adventure based out of the floating Eco-lodge, Uakari.
Tour Details
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Bird perched in the Amazon rainforest
from $1,890
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Amazon Journey

Iquitos to Nauta - 4 Day Itinerary aboard La Perla
  • Visit Pacaya Samiria National Reser
  • Admire the incredible wildlife
  • Learn more about the Amazon culture
Starts / Ends
Iquitos / Nauta
Activities
Kayaking
Activity Level
Variable
This 4-day Amazon cruise of Iquitos & Nauta aboard La Perla gives you an insider's view of life in Peru's rainforest, including piranha fishing, wildlife spotting, visit local villages, and opportunities to learn about wildlife preservation!
Cruise Details
0
Playing a charango at the local market in Otavalo, Ecuador
from $758
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Explore Otavalo Market and Valley

3 Day Itinerary
Activity Level
Relaxed
Tour Details
0
Enjoy a sightseeing trip in a canoe.
from $2,550
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Into the Wild Amazon

5 Day Itinerary aboard Tucano
  • Tour through the flooded forest
  • Learn traditions of local people
  • Watch for caiman, sloths and birds
Starts / Ends
Manaus / Manaus
Activities
Fishing
Activity Level
Variable
Board the expeditionary river boat Tucano for a 5-day exploration of Brazil's Amazon rainforest along the Rio Negro. You will have daily opportunities to venture deep into the heart of the jungle as you tour the flooded forest of Igapo, visit indigenous communities and partake in their customs & traditions, and watch out for the incredible biodiversity.
Cruise Details
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Guanacos in Torres del Paine
from $1,481
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Torres del Paine Short W Trek

Torres del Paine Trek - 5 Day Itinerary
  • Hike the famous W Trek
  • Explore Grey Glacier up close
  • Hike to the base of the towers
  • Enjoy backcountry glamping
Starts / Ends
Punta Arenas / Punta Arenas
Activity Level
Challenging
Hike & Trek the best of Patagonia in Chile's Torres del Paine National Park on this abbreviated W-Trek adventure tour. Spend five days hiking in the backcountry exploring one of the world's most spectacular parks and spotting enormous glaciers, turquoise lakes, and verdant temperate rainforests. One of the world's premier hiking trips!
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The salt flats of the Atacama Desert stretch as far as the eye can see
from $2,127
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Atacama Desert

4-5 Day Itinerary
  • Be inspired by unique geology
  • View the rainbow of desert colors
  • Experience Tatio Geyserys
  • Explore Moon Valley
Activity Level
Relaxed
Venture into the Atacama Desert! Three to five night extensions include flexible itineraries that explore this unique region, including a visit to the Valley of the Moon, and the El Tatio geysers. Evenings are spent at the renowned Terrantai Lodge in San Pedro de Atacama.
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Punto Egas, Santiago Island, Galapagos
from $5,600
LASTMINUTE
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Western Islands

8 Day Itinerary aboard Tip Top IV
  • Snorkel & swim on North Seymour
  • Navigate around Buccaneer Cove
  • Observe wildlife on Vicente Roca
  • Walk around Flamingos Lagoon
Activity Level
Variable
This Galapagos cruise aboard the Tip Top IV takes you beyond the highlights of the Western Islands with 8 days of exciting activity! Enjoy the company of friendly sea lions while snorkeling and make friends with the gentle giant tortoises in Isabela and Santa Cruz.
Cruise Details
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EcoCamp domes and Torres
from $1,371
EXPLORE

EcoCamp - Torres del Paine

4-8 Day Itinerary
  • Relax in Patagonia's eco domes
  • See the famed Torres del Paine
  • Choose from a variety of activities
Activity Level
Relaxed
Torres del Paine National Park offers a combination of unique wildlife and spectacular scenery in one of the most isolated regions of South America. Travel through Punta Arenas, Chile, or El Calafate, Argentina to arrive at EcoCamp. After full days of exploring the park return and rest in comfort in the new Suite Domes!
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Beautiful downtown Santiago at dusk
from $2,507
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South American Three City

10 Day Itinerary
  • Wine, beach & culinary tour options
  • Attend an intimate tango show
  • Visit Christ the Redeemer
  • Explore Ipanema & Copacabana
Activities
Cooking Classes
Activity Level
Relaxed
Take in the sights, sounds, food, and culture as you explore Santiago, Buenos Aires, and Rio de Janeiro. This 10 day itinerary includes free days and optional activities so you can set the pace of your South American vacation!
Tour Details
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Vineyard in Uruguay
from $1,923
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Western Vineyards of Uruguay

Colonia to Carmelo - 5 Day Itinerary
  • Experience Colonia del Sacramento
  • Enjoy wine tasting
  • Enjoy a sunset river cruise
  • Learn about the wine-making process
Starts / Ends
Puerto Carmelo / Puerto Carmelo
Activity Level
Relaxed
Spend 5 days touring the western vineyards of Uruguay while exploring Colonia del Sacramento with its rich cultural heritage and the charming area of Carmelo. Visit multiple wineries and taste their own varieties of wine.
Tour Details
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Putting on the new roof
from $861
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Sacred Valley Home Restoration

4 Day Itinerary
Activities
Homestays, Volunteering
Activity Level
Relaxed
Adventure Life's guides and partners has identified the poorest families in the Cachiccata community. The elements can cause damage to homes over time, and many families do not have the extra means to make renovations to their homes. During this 4 day/3 night trip, participants, side-by-side with the family members, will work on cleaning, repairing, and restoring their homes. We stay in the community campground each night to immerse ourselves in the village life. The trip ends with traditional Inca ceremony and offering as a time to reflect over the previous days' experiences.
Tour Details
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