Top South America Trips & Tours in September 2025

from $1,695

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Patagonian Explorer: Ushuaia to Punta Arenas

Ushuaia to Punta Arenas - 5 Day Itinerary aboard MV Ventus Australis

• Visit Cape Horn National Park
• Admire Wulaia Bay's natural beauty
• Hike at spectacular Pia Glacier

Starts / Ends

Ushuaia / Punta Arenas

Activity Level

Variable

Explore Patagonia and Tierra del Fuego on a 5-day expedition cruise aboard MV Ventus Australis from Ushuaia to Punta Arenas. This cruise offers an immersive experience through remote fjords, icy landscapes, and historic sites.

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from $4,000

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Western Islands

7 Day Itinerary aboard Bonita

• Discover Dragon Hill
• Visit Espumilla Beach
• See unique wildlife at Vicente Roce
• Hike across Urbina Bay

Starts / Ends

Baltra / Charles Darwin Center

Activities

Whale Watching

Activity Level

Variable

Embark on a Galapagos cruise aboard the Bonita. This 7-day tour of the western islands takes you to white beaches, secluded lagoons, and pristine snorkeling locations for an unforgettable week-long tour of the Galapagos.

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from $6,190

ExtendStay

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Western Islands

6 Day Itinerary aboard Ocean Spray

• Snorkel with turtles, rays and fish
• Explore Urbina Bay
• Hike along lava paths
• Take a trail along Lake Darwin

Starts / Ends

Baltra / Baltra

Activity Level

Variable

Experience Galapagos penguins, Elizabeth Bay and more on a cruise through the Western Islands. Enjoy hiking, snorkeling and dinghy rides on this 6-day Galapagos tour.

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from $4,000

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Western Islands

Baltra - Santa Cruz - 6 Day Itinerary aboard Galaxy

• Witness Galapagos Giant tortoises
• Explore Isabela's Tintoreras
• Venture into Moreno Point
• Step ashore at Espinoza Point

Starts / Ends

Baltra / Black Turtle Cove

Activity Level

Variable

Enjoy a 6-day cruise in the Western Galapagos Islands aboard the Galaxy, where you can explore enchanting landscapes teeming with unique wildlife, including giant tortoises, flamingos, iguanas, and sharks. The islands of Santa Cruz, Isabela, Fernandina, and Santiago offer an extensive array of activities for you to experience.

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from $4,920

NO SS

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Luxury Amazon Discovery - Low Water

4 Day Itinerary aboard Aqua Nera

• Visit the Manatee Rescue Center
• Journey through Jungle of Mirrors
• Discover the town of Nauta

Starts / Ends

Iquitos / Nauta

Activities

Local Market Visits, Village Visits, Rainforest Exploration, Fishing

Activity Level

Variable

Embark on this 4-day Amazon River luxury cruise on the Aqua Nera, from the Amazon port town of Iquitos. Your journey includes Yacapana Islands, Lake Clavero, Pacaya Samiria National Reserve, and the major tributaries of Ucayali and Maranon. Keep your eyes open for the mysterious pink river dolphin along the way, and enjoy activities like hiking & kayaking.

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from $2,691

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Western Islands

5 Day Itinerary aboard Galapagos Legend

• Stop at the volcanic Egas Port
• Visit Rabida's red sand beaches
• Snorkel with sea turtles

Activity Level

Variable

Explore the remote, less-visited western islands of Santa Cruz, Santiago, Isabela, Fernandina on an unforgettable 5-day cruise on the 100-passenger capacity Galapagos Legend small ship.

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from $4,245

FreeFlight

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Northern Islands

Baltra roundtrip - 5 Day Itinerary aboard Galapagos Angel

• Discover Chinese Islet lava tunnels
• Witness Sullivan Bay's geology
• Visit Darwin Bay for bird species
• Explore Egas Port

Starts / Ends

Baltra / Baltra

Activities

Hiking, Snorkeling, Wildlife Viewing, Kayaking

Activity Level

Variable

Explore North Seymour's wildlife, and discover Chinese Islet's geological wonders. Tour Sullivan Bay for captivating geology and visit Darwin Bay, El Barranco, Egas Port, and Rabida Island on this 5-day Northern Islands cruise aboard Galapagos Angel. Conclude with a visit to Fausto Llerena, observing giant tortoises in various stages of life.

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from $2,700

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Southern Islands

5 Day Itinerary aboard Bonita

• Hike over islands covered in cacti
• Kayak and stand up paddle board
• Admire distinctive biodiversity

Starts / Ends

Highlands / Bachas Beach

Activity Level

Variable

This 5-day cruise of Galapagos' Southern Islands on the Bonita yacht explores the islands of Espanola, Santa Cruz, San Cristobal and more. Kayak and paddle board along island shores, swim and snorkel among sea lions, and enjoy breathtaking views on hikes.

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from $2,700

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Central Islands + Genovesa

5 Day Itinerary aboard Bonita

• Zodiac ride in Black Turtle Cove
• Explore Darwin Bay´s coasts
• Hike through South Plaza

Starts / Ends

South Plaza Island / North Seymour

Activities

Stand Up Paddle Boarding

Activity Level

Variable

Embark on a 5-day Galapagos cruise aboard Bonita. Witness South Plazas' wildlife, explore Black Turtle Cove's mangroves, visit highlands for Giant tortoises, and discover Genovesa's seabird colonies. Experience the volcanic landscapes of Bartolome with penguins and frigatebirds. Marvel at unique fauna on this remarkable island adventure.

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from $2,590

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Chonos Route

Puerto Montt Roundtrip - 6 Day Itinerary aboard MV Skorpios II

• Explore picturesque Chiloe Island
• Explore fishing town Puerto Aguirre
• Whale watch on the Corcovado Gulf
• Visit San Rafael Glacier

Starts / Ends

Puerto Montt / Puerto Montt

Activity Level

Variable

Embark on a 6-day cruise aboard MV Skorpios II, beginning and ending in Puerto Montt, and sail over 800 miles through the magical age-old ice formations, glaciers, stunning archipelagos, channels, and small gulfs. Admire the vast island-peppered sea as you disembark to explore small towns and soak in the region's famed hot springs.

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from $1,938

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Inca Trail Express

5 Day Itinerary

Activities

Camping

Activity Level

Challenging

This 5-day trip spends 4 days hiking the Inca Trail then visits Machu Picchu for a full day exploring the ruins. Hike with expert guides and enjoy deluxe camping to assure the best possible experience. Travelers are required to spend a minimum of two nights at high altitude before the trek, usually in Cusco, Sacred Valley, or Lake Titicaca.

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from $1,575

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Rio de Janeiro and Iguazu Falls

7 Day Itinerary

• Tour Rio de Janeiro's city center
• Enjoy views from Sugarloaf Mountain
• Discover the beautiful Iguazu Falls
• Walk above the spectacular falls

Starts / Ends

Rio de Janeiro / Iguazu Falls

Activities

Urban Exploration

Activity Level

Relaxed

This 7-day tour combines Rio de Janeiro, "The Marvelous City" a highlight on any Brazil tour, with Iguazu Falls, one of the most awe-inspiring sights in South America. The falls straddle the border between Argentina and Brazil, explore the falls to get up close to the plummeting water.

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from $1,500

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Tambopata Research Center

5 Day Itinerary

• Climb a 30-meter tree
• Watch the sunset with wine
• Visit the Colorado clay lick

Activities

Wilderness Lodge Exploration

Activity Level

Easy Active

Explore the Amazon rainforest on this 5-day tour from Puerto Maldonado. Hike on the floodplain trails, search for frogs at night, and look for the gleaming eyes of the caiman during your stay at the comfortable and enthralling Tambopata Research Center.

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from $357

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Andean Horseback Riding

½ Day Itinerary

Activities

Archaeological Site Visits, Horseback Riding

Activity Level

Easy Active

Saddle up, partner, for this exciting half-day horseback riding tour from Cusco. Over the course of 2 1/2 hours, ride through fields, Inca sites, and small villages en route to the impressive Temple of the Moon, which you are welcome to explore on foot.

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from $475

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Lake Titicaca with Homestay

4 Day Itinerary

Activities

Homestays

Activity Level

Relaxed

This 4-day Peru extension tour of Lake Titicaca gives you an in-depth cultural experience interacting with the local community whose roots date back to ancient cultures that settled in this area. Their hospitality opens a door to share with their families and offers you a homestay opportunity on Amantani Island.

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from $322

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Trek and Paddle Tierra del Fuego National Park

1 Day Itinerary

• Visit Tierra del Fuego Nat'l Park
• See Lapataia Bay's albatross
• Canoe ride to Laguna Verde

Activity Level

Easy Active

This full-day adventure in Tierra del Fuego National Park includes hiking and paddling. A canoe excursion to Lapataia Bay, which is home to petrels, albatross, steamer ducks, and penguins, is among the highlights.

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from $265

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Maras and Moray Mountain Biking

1 Day Itinerary

Activities

Biking

Activity Level

Moderate

Your bike is your ticket to adventure on this day tour of Maras & Moray in the Peruvian Andes. A 7-hour tour takes you to Maras Plateau, through the towering peaks of the Andes, to local villages, and even to an experimental agricultural terrace of the Inca at Moray. Be prepared for a high energy day!

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from $248

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Vilcanota-Urubamba River Whitewater Rafting

1 Day Itinerary

Activities

Whitewater Rafting

Activity Level

Moderate

Embark on an exciting day-tour for whitewater rafting down the Urubamba River, taking you through Class II & III rapids. You will see fantastic views and pass through archaeological sites en route to Ollantaytambo. The rafting ends with an exciting trip through El Resbaladero including waves and small whirlpools.

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