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Top New Orleans Trips & Tours in September 2025

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Discover New Orleans in September 2025 on one of these 3 tours hand-selected by the travel experts at Adventure Life. Explore the best of during September 2025 as you enjoy Archaeological Site Visits, Village Visits, Local Market Visits, Urban Exploration, and Biking. Prices for trips in September 2025 range from $4,925 to $30,999 for a vacation of 9 to 16 days. Choose any of the below 3 itineraries in September 2025 and customize it when you contact one of Adventure Life's expert New Orleans trip planners.
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    • New Orleans
Vibrant Sunset with St. Paul City Skyline and Mississippi Riverfront
from $12,620
Savings
EXPLORE

Grand Heartland Cruise

Minnesota - Louisiana - 16 Day Itinerary aboard American Serenade
  • Visit mansions and art galleries
  • See the Gateway Arch and St. Louis
  • Visit Natchez’s antebellum homes
  • Experience Memphis' musical legacy
Starts / Ends
St. Paul / New Orleans
Activities
Wine Tasting, Wildlife Viewing, Biking
Activity Level
Variable
Embark on a 16-day Mississippi River cruise from Minnesota to Louisiana aboard American Serenade, exploring St. Paul to New Orleans with stops in La Crosse, Dubuque, Davenport, Hannibal, St. Louis, Memphis, Vicksburg, and Natchez. Enjoy onboard activities, stunning scenery, and experiences like the Mark Twain Boyhood Home and more.
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View the iconic arch when you visit St. Louis, gateway to the west
from $13,999
EXPLORE

America’s Great River

St. Paul to New Orleans - 15 Day Itinerary aboard Viking Mississippi
  • Explore St. Louis' arts scene
  • Enjoy American music styles
  • Learn Civil War history
  • Experience New Orleans' culture
  • Visit the Quad Cities
Starts / Ends
St. Paul / New Orleans
Activity Level
Variable
Cruise America's great river on this 15-day itinerary aboard Viking Mississippi. Journey from St. Paul, Minnesota to New Orleans, Louisiana and explore highlights of the mighty Mississippi River. Along the way, visit historic ports such as St. Louis, Memphis, Baton Rouge, and more.
Cruise Details
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Visit Louisiana's capital city of Baton Rouge
from $4,925
Savings
EXPLORE

Lower Mississippi River Cruise

Memphis - New Orleans - 9 Day Itinerary aboard American Splendor
  • Admire the diversity of New Orleans
  • Discover the cultures of the delta
  • Learn the history of Vicksburg
  • Enjoy the music of Memphis
Starts / Ends
Memphis / New Orleans
Activities
Village Visits, Archaeological Site Visits, Urban Exploration, Local Market Visits
Activity Level
Variable
Experience a 9-day cruise aboard American Heritage from Memphis to New Orleans, discovering historic sites, Civil War stories, and charming towns along the Mississippi River. Experience rich history, music, and southern hospitality.
Cruise Details
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TrustScore 4.8 | 567 reviews
TrustScore 4.8 of 5
total score
Based on 567 reviews on
review score
3 months ago
Betty was extremely helpful and friendly! I have never traveled by long boat and was nervous about the options and the experience. Betty listened carefully to my wants and needs and presented exactly what my sister and I hoped for! I couldn’t have asked a more pleasant experience - I am so excited about our trip!!
Jan Struck

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