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Explore the coastlines of the Great Lakes

Ohio River Cruises

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Embark on a journey through time in Marietta, Ohio, with our 1 unique archaeological site visits designed for 2025. This city, rich in history and nestled along the confluence of the Muskingum and Ohio rivers, offers an intimate glimpse into America's past. Over a span of 16 days, you'll engage with the heritage that shaped this region aboard the elegant American Countess during your river cruise. With prices beginning at just $9,240 to $16,230, delve into Marietta's storied museums and uncover historical treasures that tell tales of yesteryear. Savor village visits where local lore comes alive amidst charming Americana culture. To discover more about these immersive experiences that connect you to America’s heartland history, contact one of Adventure Life's tour specialists for help planning your next seamless trip.
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View the iconic arch when you visit St. Louis, gateway to the west
from $9,240
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Grand Ohio River Cruise

Pittsburgh to St. Louis - 16 Day Itinerary aboard American Melody
  • Explore historic Marietta, Ohio
  • Explore Maysville’s Railroad
  • Visit Louisville’s Churchill Downs
  • Tour Paducah’s wall murals
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Pittsburgh / St. Louis
Activities
Wildlife Viewing, Village Visits, Urban Exploration, Archaeological Site Visits
Activity Level
Variable
Sail from Pittsburgh to St. Louis on a 16-day Ohio River cruise aboard American Melody. Visit historic towns like Marietta, Cincinnati, Louisville, and Paducah. Discover museums, landmark sites, and cultural excursions while enjoying daily enrichment programs and scenic cruising.
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