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Top United States Trips & Tours in September 2025

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Discover United States in September 2025 on one of these 30 tours hand-selected by the travel experts at Adventure Life. Explore the best of Juneau, Glacier Bay National Park, Icy Strait, Chichagof Island, and Sitka during September 2025 as you enjoy cruises, wildlife viewing, kayaking, hiking, and wildlife & safari exploration. Prices for trips in September 2025 range from $1,330 to $30,999 for a vacation of 5 to 16 days. Choose any of the below 30 itineraries in September 2025 and customize it when you contact one of Adventure Life's expert United States trip planners.
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Spot the Northern Lights. Credit Arturo Polo Ena.
$12,500
EXPLORE

Remote Alaska Adventure

5 Day Itinerary
  • Adventure on flight-safari tours
  • Stay in comfortable cabins
  • Spot a variety of wildlife
  • Adventure on foot, by kayak, or ski
Activities:
Fishing, Hiking, Kayaking, Land, Skiing, Wilderness Lodge, Wildlife Viewing
Activity Level:
Easy Active
Ultima Thule Lodge combines the wild adventure of an Alaska wilderness lodge with all the creature comforts expected with high-end hotels. Add in the daily plane safari adventures and the customized experiences for groups of just two people, and you will find yourself feeling like family at this …
Tour Details
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View the iconic arch when you visit St. Louis, gateway to the west
$13,999
EXPLORE

America’s Great River

St. Paul to New Orleans - 15 Day Itinerary aboard Viking Mississippi
  • Explore St. Louis' arts scene
  • Enjoy American music styles
  • Learn Civil War history
  • Experience New Orleans' culture
  • Visit the Quad Cities
Starts / Ends:
St. Paul / New Orleans
Activities:
Archaeological Site Visits, River Cruises, Village Visits
Activity Level:
Relaxed
Discover the history, natural beauty, and distinctive regional cultures of America's great river, the mighty Mississippi, on this 15-day cruise aboard Viking Mississippi. Set sail from St. Paul, Minnesota, and venture south toward New Orleans, Louisiana. Along the way, visit small towns and …
Cruise Details
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Whale watching in Alaska
$7,200
EXPLORE

Inside Passage & Glacier Bay Wilderness Cruise

13 Day Itinerary aboard Safari Explorer
  • Enjoy Canada’s Inside Passages
  • Visit Glacier Bay National Park
  • Discover LeConte Bay
  • Watch for whales at Frederick Sound
Starts / Ends:
Seattle / Juneau
Activities:
Hiking, Kayaking, Village Visits, Whale Watching, Wildlife Viewing
Activity Level:
Relaxed
Discover a wilderness beyond the expected on a 13-day Alaskan journey through Inside Passages and Glacier Bay National Park. Enjoy adventure activities in the San Juan Islands, Tongass National Forest, and Misty Fjords National Monument. Learn more about the Native culture and Pacific …
Cruise Details
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Bear taking a drink
$4,250
EXPLORE

Alaska Bear-Viewing Lodge

4-5 Day Itinerary
  • Watch bears up-close with a guide
  • Spot otters, seals, and foxes
  • Enjoy the rustic comfort of a cabin
Activities:
Wilderness Lodge Exploration, Wildlife Viewing
Activity Level:
Easy Active
Enjoy 4 days in the remote Alaska wilderness bear viewing at Katmai Wilderness Lodge. This remote Alaska lodge experience is a perfect add-on to any Alaska cruise or Alaska tour, offering you the chance to explore the remote Alaska wilderness with experienced guides. Here you find the perfect …
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Calm waters disturbed only by the flick of a whale's tail
$5,112
EXPLORE

Wild Alaska Escape: Sitka to Juneau

6 Day Itinerary aboard National Geographic Sea Lion
  • Journey by kayak into dramatic bays
  • Raft the Chilkat River with guides
  • See Haines by raft, bike, or foot
  • View glaciers and icebergs
Starts / Ends:
Sitka / Juneau
Activities:
Hiking, Kayaking, Small Ship Cruises, Village Visits, Whale Watching, Wildlife Viewing
Activity Level:
Relaxed
Board the National Geographic Sea Lion on this 6-day cruise to explore Alaska on an active expedition to see the region’s iconic wildlife and epic landscapes in a compact timeframe. Enjoy hikes on world-class trails through forests of towering trees, kayak deep into glacially-carved fjords, …
Cruise Details
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Moose found on an Alaska wildlife tour
$4,400
EXPLORE

Glacier Bay National Park Adventure

8 Day Itinerary aboard Wilderness Discoverer
  • Discover Glacier Bay National Park
  • Admire Alaskan wildlife
  • Visit Grand Pacific Glacier
  • Hike down Fairweather Mountain
Starts / Ends:
Juneau / Juneau
Activities:
Adventure Options, Hiking, Kayaking, Small Ship Cruises, Stand Up Paddle Boarding, Wildlife Viewing
Activity Level:
Relaxed
Discover the unique Glacier Bay National Park, home to the world's largest marine sanctuary. From kelp-lined channels to hemlock and spruce forests, every inch of this remote land is worth exploring. This dazzling voyage offers the opportunity to admire the exotic wildlife of this region. Keep …
Cruise Details
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Ultimate Alaska
$8,957
EXPLORE

Ultimate Alaska

14 Day Itinerary
  • Hike & camp Alaska's backcountry
  • Kayak & camp near Columbia Glacier
  • Walk and ice climb on Root Glacier
  • Raft down the Kennicott River
Activities:
Camping, Hiking, Land, Whitewater Rafting, Wildlife Viewing
Activity Level:
Challenging
This two week Alaska trip is designed for the avid adventurer desiring to minimize transit time and maximize remote active experiences while on vacation in Alaska. Hike Alaska's remote and unspoiled wilderness area of Wrangell - St. Elias National Park on a multi-day basecamp and hiking tour. …
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Family hiking on a tour of Alaska
$5,600
EXPLORE

Northern Passages & Glacier Bay

8 Day Itinerary aboard Safari Endeavour
  • Attend Park Ranger presentations
  • Hike at Glacier Bay National Park
  • Spot bears, otters, and whales
  • See Krestof and Nakwasina Sounds
  • Observe puffins and sea lions
Activities:
Hiking, Kayaking, Small Ship Cruises, Stand Up Paddle Boarding, Whale Watching, Wildlife Viewing
Activity Level:
Relaxed
Journey into the crown jewel of the U.S. National Park System on this 8-day cruise aboard the Safari Endeavour. Explore Glacier Bay, a UNESCO World Heritage Site, via kayak, paddleboard, snorkel, or boat. Highlights include trips to Glacier Bay National Park and Chichagof Islands' waterfall …
Cruise Details
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Sunrise over Crown Point at Columbia River
$4,949
EXPLORE

Clarkston (Spokane) to Vancouver (Portland)

Spokane to Portland - 9 Day Itinerary aboard American Empress
  • Explore Astoria
  • Experience the Pacific Northwest
  • Enjoy Pacific Northwest wineries
  • Participate in luxury wine tasting
Starts / Ends:
Astoria / Clarkston
Activities:
Biking, Kayaking, River Cruises, Wildlife Viewing
Activity Level:
Relaxed
Discover the best of the Pacific Northwest on this 9-day voyage from Clarkston to Vancouveraboard American Empress. Embark on a river cruise to see that the natural world is alive here – unlike anywhere else on earth – and through historic sites and locks and dams, it flows. Sea lions …
Cruise Details
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A bear catches a fish as it swims upstream
$5,901
EXPLORE

Voyage to Great Bear Rainforest: Native Culture & Wildlife in the Land of the Spirit Bear

8 Day Itinerary aboard National Geographic Venture
  • Kayak across Great Bear
  • Look our for Kermode bears
  • Swim at hot spring pools
  • Experience unique landscapes
Starts / Ends:
Ketchikan / Ketchikan
Activities:
Hiking, Kayaking, Rainforest Exploration, Small Ship Cruises, Wildlife Viewing
Activity Level:
Relaxed
Sail into northern British Columbia's tiny, meandering fjords and enter the domain of the endangered Spirit Bear. Also known as a Kermode bear, it is a subspecies of the North American black bear that is found exclusively in the Great Bear Rainforest's pristine wildness. The forest is …
Cruise Details
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Kayaking Tracy Arm Fjord in Tongass National Forest.
$8,106
EXPLORE

Exploring Alaska's Coastal Wilderness

8 Day Itinerary aboard National Geographic Quest
  • View unique wildlife such as orcas
  • Visit Tracy or Endicott Arm fjords
  • Explore Alaskan ecosystems
  • Hike & kayak in Icy Strait
Activities:
Hiking, Kayaking, Small Ship Cruises, Whale Watching, Wildlife Viewing
Activity Level:
Relaxed
Discover a unique, immersive style of travel as you explore Southeast Alaska on this unrivaled expedition. The National Geographic Quest isfully equipped with tools for exploration that enable you to enjoy the magnificent landscapes of coastal Alaska. This voyage brings ample wildlife viewing …
Cruise Details
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Visit historic St. Louis
$4,019
EXPLORE

St. Louis to Minneapolis

9 Day Itinerary aboard American Countess
  • Explore the culture of St. Louis
  • See Mark Twains hometown, Hannibal
  • Relax in laid-back La Crosse
  • Admire local artwork in Red Wing
Starts / Ends:
St. Louis / Red Wing
Activities:
Archaeological Site Visits, River Cruises, Village Visits
Activity Level:
Relaxed
Explore the country and river that inspired Mark Twain, the pen name of the famed American novelist Samuel Clemens. From St. Louis, Missouri, cruise north along the magnificent Mississippi River towards Minneapolis. Explore port towns such as Hannibal, Missouri, the birthplace of Mark Twain, and …
Cruise Details
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Bald eagles resting
$12,103
EXPLORE

Treasures of the Inside Passage: Alaska and British Columbia

14 Day Itinerary aboard National Geographic Quest
  • Explore the San Juan Islands
  • Observe a traditional performance
  • Learn about the local cultures
  • Search for humpback whales
  • Kayak Misty Fjord’s waters
Activities:
Hiking, Kayaking, Small Ship Cruises, Whale Watching, Wildlife Viewing
Activity Level:
Relaxed
Join the National Geographic Queston a 14-day in-depth exploration of the San Juan Islands, British Columbia, and Alaska. Linger in the temperate rain forests and wildlife-rich channels of British Columbia, and enjoy ample time to discover the breathtaking fjords and towering glaciers of Southeast …
Cruise Details
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Sunrise from the deck over the fjord
$4,148
EXPLORE

Kenai Explorer

7 Day Itinerary
  • Stay in a remote Kenai Fjords Lodge
  • Spot seal, sea otters, and birdlife
  • Go on a dog-sled adventure
  • Walk on the Exit Glacier in Seward
Activities:
Hiking, Kayaking, Land, Wilderness Lodge, Wildlife Viewing
Activity Level:
Easy Active
Spend seven days exploring the southern area near Seward, Alaska including the vast and stunning Kenai Fjords National Park. Rest one night at a wilderness lodge in Cooper Landing, then travel further to Kenai Fjords Glacier Lodge. Spend time paddling, boating and spotting wildlife during your stay …
Tour Details
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Sunrise over Crown Point at Columbia River
$5,229
EXPLORE

Vancouver (Portland) to Clarkston (Spokane)

Vancouver to Clarkston - 9 Day Itinerary aboard American Empress
  • Explore Astoria
  • Experience the Pacific Northwest
  • Jet boat through Hells Canyon
  • Discover the Lewis & Clark journey
Starts / Ends:
Astoria / Clarkston
Activities:
Biking, Kayaking, River Cruises, Wildlife Viewing, Wine Tasting
Activity Level:
Relaxed
Discover the best of the Pacific Northwest on this 9-day voyage from Vancouver, Washington to Clarkston, Washington aboard American Empress. Sail the Columbia and Snake rivers to explore the region's stunning coast, lush rainforests, and scenic mountains. Discover incredible hiking, biking, and …
Cruise Details
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Fireweed blooms before majestic Denali
$5,600
EXPLORE

Denali and Talkeetna Wilderness Rail Adventure

7 Day Itinerary
  • Explore Denali National Park
  • Guided hikes and kayak excursions
  • Wildlife Encounters
  • Discover historic Talkeetna
Starts / Ends:
Anchorage / Anchorage
Activities:
Helicopter Tours, Hiking, Kayaking, Urban Exploration, Wildlife Viewing
Activity Level:
Relaxed
This fully-escorted Denali National Park and Talkeetna exploration stays true to the spirit of adventure. Put your boots to the ground and experience an unmatched, up-close, and hands-on 7-day experience in Alaska's interior. Travel by bus and first class rail as you travel cabin to rustic …
Tour Details
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Kayaking around Alaska
$4,800
EXPLORE

Wild, Woolly and Wow: Best of Glacier Bay

8 Day Itinerary aboard Wilderness Legacy
  • Explore Glacier Bay National Park
  • Discover LeConte and Baird Glacier
  • Enjoy wildlife searches
  • Experience active adventures
Starts / Ends:
Juneau / Juneau
Activities:
Kayaking, Small Ship Cruises, Stand Up Paddle Boarding, Whale Watching, Wildlife Viewing
Activity Level:
Relaxed
Embark the Wilderness Legacy for this 8-day voyage that takes you into the jewel of the US National Park System.Join fellow adventurers on the most active back-country itinerary that UnCruise offers. See areas that no other boats visit, and stretch your legs and imagination in all new areas. Enjoy …
Cruise Details
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Kayaking in Aialik Bay
$3,447
EXPLORE

Kenai Fjords Glacier Lodge

5 Day Itinerary
  • Cozy log cabins offer glacier views
  • Explore by canoe, kayak, and boat
  • Spot wildlife and stunning glaciers
Starts / Ends:
Anchorage / Anchorage
Activities:
Kayaking, Land Tours, Wilderness Lodge Exploration, Wildlife Viewing
Activity Level:
Easy Active
Travel to the Kenai Fjords Glacier Lodge - the only lodge exclusively located within the Kenai Fjords National Park boundaries. Spend three days here exploring this Alaskan glacial paradise as you beachcomb, boat, canoe and kayak throughout the bays spotting wildlife and enjoying a remote Alaska …
Tour Details
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