Have questions? We're here.
Coast of Ortigia island at city of Syracuse

Top Syracuse Tours & Cruises in 2025

Travel made your way ™
Talk with an expert
Build your ideal Mediterranean trip. Call 1.406.541.2677
Start Planning My Trip
Talk with an expert
Discover the best the world has to offer with Adventure Life’s expert-curated Syracuse tours 2025. From to hidden gems off the beaten path, our 15 top-rated itineraries take you deep into Syracuse’s breathtaking landscapes. Guided by bilingual experts, these immersive experiences cater to adventurers seeking unique journeys in small groups or customizable private tours.

Choose from a variety of 8 to 21 days itineraries starting at $2,460 to $30,850. You’ll find options that suit your travel style. Whether you’re passionate about Archaeological Site Visits, Village Visits, Wine Tasting, Small Ship Sailing, and Hiking or eager to explore Syracuse’s rich culture and natural beauty, our Syracuse tours 2025 deliver unforgettable moments. Each itinerary blends awe-inspiring exploration with a commitment to sustainability to ensure your adventure supports the preservation of our planet.

Adventure Life’s dedication to personalized travel promises your Syracuse tour 2025 is seamless from start to finish. From arranging transportation to selecting accommodations tailored to your preferences, we’ll take care of every detail. Our expert recommendations and insider tips make your journey even more enriching.

Contact our specialists today to start planning your Syracuse tour 2025. Whether you’re a solo traveler, a couple, or part of a group, Adventure Life will create a transformative experience you’ll treasure forever.
Filter (15 Results)
  • Start Date
    OR, More specific start
  • Length
    to
  • Price
    to
  • Activity Levels
  • Experiences
  • Activities
  • Ships
  • Destinations
    • Syracuse
Coast of Ortigia island at city of Syracuse
from $2,590
EXPLORE

Sicily & Greece

Piraeus - Valletta - 9 Day Itinerary aboard Star Clipper
Starts / Ends
Piraeus / Valletta
Activity Level
Variable
Set sail on a 9-day cruise with Star Clipper, exploring Greece, Sicily, and Malta. Discover ancient sites, stunning landscapes, and cultural gems from Athens to Valletta while enjoying the charm of your ship.
  • Explore Piraeus port city
  • Wander Nafplio charming town
  • Discover Monemvasia fortress
  • Visit Syracuse ruins
Cruise Details
0
Cruise into charming Sicily
from $2,460
EXPLORE

Amalfi & Sicily

Roundtrip Civitavecchia - 8 Day Itinerary aboard Royal Clipper
Starts / Ends
Civitavecchia / Civitavecchia
Activity Level
Variable
Set sail on an 8-day cruise aboard the Royal Clipper, exploring Italy and Sicily with stops in Civitavecchia, Sorrento, Amalfi, Taormina, and Syracuse. Enjoy volcanic views at the Aeolian Islands and optional excursions to Pompeii while experiencing Mediterranean beauty and history.
  • Explore Civitavecchia seaport hub
  • Wander Sorrento’s cliffside lanes
  • Visit Pompeii’s preserved ruins
  • Admire Amalfi’s medieval Duomo
Cruise Details
0
Explore historic Bonifacio atop the cliffs of Corsica
from $8,920
EXPLORE

Mediterranean Island Voyage: Sicily, Sardinia, Corsica, and Elba – with Smithsonian Journeys

Valletta - Nice - 8 Day Itinerary aboard Le Bougainville
Starts / Ends
Valletta / Nice
Activities
Land & Sea Exploration
Activity Level
Variable
Explore the heart of the Mediterranean on this 8-day Mediterranean Island Cruise with Smithsonian Journeys from Valletta to Nice aboard Le Bougainville. Discover Sicily, Sardinia, Corsica, and Elba's historical civilizations that left mark on these islands' language, cuisine, art, and architecture.
  • Discover Mediterranean islands
  • Experience ancient ruins
  • Admire Byzantine-Arab mosaics
  • Explore medieval towns
  • Discover local cuisine
Cruise Details
0
Explore ruins in Taormina within view of volcanic Mount Etna
from $3,699
2for1
EXPLORE

La Dolce Vita

Naples - Malta - 8 Day Itinerary aboard Variety Voyager
Starts / Ends
Naples / Valletta
Activity Level
Variable
Embark on an 8-day cruise aboard the Variety Voyager from Naples to Malta, visiting Capri, Taormina, Mount Etna, and Catania in Sicily. In Malta, explore Valletta's UNESCO sites and Gozo's ancient monuments.
  • Explore Capri's coastal allure
  • Visit Lipari’s ancient sites
  • Discover Taormina’s historic alleys
  • Wander Syracuse’s ancient streets
Cruise Details
0
Coast of Ortigia island at city of Syracuse
from $6,690
EXPLORE

Ancient Jewels of the Mediterranean

Valletta - Athens - 8 Day Itinerary aboard Le Dumont-d'Urville
Starts / Ends
Valletta / Athens
Activity Level
Variable
Set sail on an 8-day Ancient Jewels of the Mediterranean cruise aboard Le Dumont-d'Urville! Explore Malta's coast and Greece's treasures. Discover Syracuse's puppetry, Paros' villages, and Taormina's ancient theatre. Experience Gallipoli, Galaxidi, Hydra, and Paros.
  • Meet a famous puppeteer in Syracuse
  • Immerse in Southern Italy
  • Wander through the ancient streets
Cruise Details
0
Coast of Ortigia island at city of Syracuse
from $5,510
EXPLORE

Ancient Jewels of the Mediterranean

Athens - Valletta - 8 Day Itinerary aboard L'Austral
Starts / Ends
Athens / Valletta
Activity Level
Variable
Embark on an 8-day adventure on L’Austral from Athens to the Maltese coast. Enjoy excursions at each port, including visits to Hydra's monuments, Paros, and Galaxidi. In southern Italy, discover Gallipoli's Greek heritage, Taormina's ancient theatre, and Ortygia's historic streets. The cruise concludes in Valletta, the capital of Malta.
  • Meet a famous puppeteer in Syracuse
  • Discover Southern Italy's history
  • Cross the Corinth Canal to Galaxidi
  • Explore Paros and its white marbles
Cruise Details
0
Blue hour over the city in the shadow of Mount Etna
from $3,699
2for1
EXPLORE

Mediterranean Serenade

Roundtrip Malta - 8 Day Itinerary aboard Variety Voyager
Starts / Ends
Valletta / Valletta
Activity Level
Variable
Embark on an 8-day cruise to and from Malta aboard the Variety Voyager. Discover the UNESCO World Heritage Ggantija temples on Gozo Island and Lipari in Sicily. Ascend Mount Etna and explore iconic "The Godfather" filming locations.
  • Explore Gozo’s ancient temples
  • Discover Syracuse’s history
  • Taste Lipari’s finest wines
  • Swim in Malta’s waters
Cruise Details
0
Visit the Baroque Cathedral of Syracuse
from $8,220
EXPLORE

Cruising Southern Italy and Sicily – with Smithsonian Journeys

Valletta - Livorno - 9 Day Itinerary aboard Le Dumont-d'Urville
Starts / Ends
Valletta / Livorno
Activity Level
Variable
Sail on this 9-day Southern Italy and Sicily cruise with Smithsonian Journeys aboard Le Dumont-d'Urville. Start in Valletta, Malta, exploring historic landmarks. Visit Syracuse's Greek and cultural sites and Taormina's scenic views and theater. Explore Reggio di Calabria's coast and museum. Visit Civitavecchia, and conclude in Livorno, Tuscany.
  • Explore Valletta's heritage
  • Discover Syracuse's history
  • Admire Taormina's scenic views
  • Experience Naples culture
Cruise Details
0
Tour the charming city of Valletta, Malta.
from $10,260
EXPLORE

A Circumnavigation of Sicily with Smithsonian Journeys

Valletta - Valletta - 9 Day Itinerary aboard Le Bougainville
Starts / Ends
Valletta / Valletta
Activity Level
Variable
During this 9-day cruise around Sicily aboard the new luxury expedition ship Le Bougainville, you'll be able to explore mythical places at the crossroads of Eastern and Western civilizations. Discover Sicily's most beautiful historic cities and ancient sites.
  • Take a loop around Sicily
  • Discover Sicily's beautiful cities
  • Visit Syracuse
  • Explore Palermo
Cruise Details
0
Beautiful Taormina, Italy, with Mt. Etna in the background
from $9,920
EXPLORE

Epicurean Delights of Sicily and the Adriatic Coast of Italy

Valletta to Venice - 9 Day Itinerary aboard Le Bougainville
Starts / Ends
Valletta / Venice
Activities
Small Ship Sailing, Wine Tasting
Activity Level
Variable
Embark on a 9-day Le Bougainville trip through Sicily and Italy’s Adriatic coast, visiting UNESCO sites like Valletta, Syracuse, and Venice. Explore ancient ruins, Baroque cities, and medieval towns, while enjoying local wines, cheeses, and dishes prepared by chef Denny Imbroisi.
  • Visit Valletta's UNESCO sites
  • Explore ancient Syracuse ruins
  • Visit Taormina's Greek Theater
  • Savor Apulian wine and food
  • Discover Venice’s hidden gardens
  • Enjoy Ravenna's stunning mosaics
  • Mount Etna wine tasting
Cruise Details
0
Visit charming Sicily
from $3,000
EXPLORE

Treasures of Sicily

Italy Small Group Tour - 9 Day Itinerary
Starts / Ends
Viagrande / Taormina
Activities
Hiking
Activity Level
Relaxed
Spend 9 days on this small group journey through the treasures of Sicily to step into a world where ancient ruins stand alongside vibrant cities and picturesque landscapes. Discover ancient ruins, bask in the island's natural beauty, and indulge in Sicily's culinary delights.
  • Visit the Island of Sicily
  • Discover the Valley of the Temples
  • Visit Taormina's ancient ruins
  • See the Mount Etna in Sicily
  • Explore the coastal town of Cefalu
  • Visit Syracuse's Archeological Park
  • Discover the Zingaro Nature Reserve
Tour Details
0
from $9,540
EXPLORE

Culture and Islands of the Mediterranean

Barcelona - Valletta - 12 Day Itinerary aboard L'Austral
Starts / Ends
Barcelona / Valletta
Activities
Urban Exploration
Activity Level
Variable
Embark on a 12-day cruise from Barcelona to Malta aboard L’Austral. Enjoy culinary and cultural experiences with an included excursion per port. Highlights include Menorca, Alghero, Cagliari, Trapani, Palermo, Lipari, Catania, Syracuse, Gozo, and ending in Valletta.
  • Visit Menorca
  • Explore Sardinia
  • Discover Sicily
  • Experience Catania
  • Discover Syracuse
  • Discover Malta
Cruise Details
0
Visit beautiful Hydra
from $10,390
EXPLORE

Ancient Wonders of the Mediterranean

Athens - Valletta - 13 Day Itinerary aboard Le Dumont-d'Urville
Starts / Ends
Athens / Valletta
Activity Level
Variable
Embark on a 13-day Mediterranean cruise aboard Le Dumont-d'Urville, exploring the enchanting destinations of Greece, Turkey, and Italy. Each destination offers unique experiences, from ancient ruins and historic monasteries to stunning beaches and charming villages.
  • Explore the rocky plateau of Athens
  • Explore Patmos
  • Admire volcanic beauty and ruins
  • Explore the Delphi Sanctuary
Cruise Details
0
Explore ruins in Taormina within view of volcanic Mount Etna
from $6,170
EXPLORE

Grand Voyage: Rome to Lisbon

Civitavecchia - Lisbon - 21 Day Itinerary aboard Royal Clipper
Starts / Ends
Civitavecchia / Lisbon
Activities
Archaeological Site Visits, Village Visits, Local Market Visits, Wildlife Viewing
Activity Level
Variable
Embark on a 21-day cruise aboard the Royal Clipper from Rome to Lisbon, exploring stunning cities like the Amalfi Coast, Sicily, and the Balearic Islands. Enjoy optional excursions to historic sites while relaxing onboard with sailing and adventure activities amidst breathtaking landscapes.
  • Explore Sorrento’s coastal cliffs
  • Wander Amalfi’s medieval streets
  • Uncover Syracuse’s history
  • Admire Lipari’s vibrant marina
Cruise Details
0
Beautiful Taormina, Italy, with Mt. Etna in the background
from $5,750
EXPLORE

Ancient Jewels of the Mediterranean

Valletta - Athens - 8 Day Itinerary aboard Le Bougainville
Starts / Ends
Valletta / Athens
Activity Level
Variable
Set sail on an 8-day Ancient Jewels of the Mediterranean cruise aboard Le Bougainville. Explore Malta's coast and Greece's treasures. Discover Syracuse's puppetry, Paros' villages, and Taormina's ancient theatre. Experience Gallipoli, Galaxidi, Hydra, and Paros.
  • Meet a famous puppeteer in Syracuse
  • Immerse in Southern Italy
  • Wander through the ancient streets
  • Visit the Taormina in Sicily
Cruise Details
0
1-15 of 15 Results
  • 1

Mediterranean Travel Guide

Favorite Mediterranean Mediterranean All Trips

Top Mediterranean Travel Destinations

Mediterranean Trips by Departure Date

Top Experiences in Mediterranean

Mediterranean Trips by Duration

Mediterranean Trips by Activity

More Reasons

Why Travel With Adventure Life

All News

Recognized By

Clara Tort Adventure Life employee profile
Clara T
Plan My Trip
We love travel, talk with an expert 1.800.344.6118
GOT IT!
We use cookies to give you the best experience on our website. Continue browsing the site if you're ok with this. For more info, please see our privacy policy.