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Coast of Ortigia island at city of Syracuse

Top Syracuse Tours & Cruises in 2025

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Discover Syracuse in 2025 on one of these trips hand selected by the travel experts at Adventure Life. Select any of the below 5 top-rated trips where you will explore Syracuse with an exceptional bilingual guide on a small group or customizable private tour. The most popular things to do in Syracuse in are cruises, small ship cruises, and archaeological site visits. Our Syracuse trips in 2025 range in price from $2,190 to $29,900 for trips of 8 to 16 days. Contact one of Adventure Life's expert Syracuse trip planners for help planning a seamless experience.
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Cruise into charming Sicily
$2,190
EXPLORE

Amalfi & Sicily

Civitavecchia Round-trip - 8 Day Itinerary aboard Royal Clipper
  • Gaze upon the Sistine Chapel
  • Snorkel at Palmarola
  • Visit historical Pompeii
  • Wander through the grand Duomo
Starts / Ends:
Civitavecchia / Civitavecchia
Activities:
Archaeological Site Visits, Small Ship Cruises, Small Ship Sailing
Activity Level:
Relaxed
Embark on an 8-day cruise aboard Royal Clipper through Amalfi and Sicily! Explore Rome's iconic landmarks like St. Peter's and the Colosseum before hitting Sorrento's stunning coast. Dive into history at Pompeii and relish Amalfi's medieval charm, from its Duomo to the picturesque …
Cruise Details
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Tour the charming city of Valletta, Malta.
$7,420
EXPLORE

A Circumnavigation of Sicily with Smithsonian Journeys

Valletta - Valletta - 9 Day Itinerary aboard Le Bougainville
  • Take a loop around Sicily
  • Discover Sicily's beautiful cities
  • Visit Syracuse
  • Explore Palermo
Starts / Ends:
Valletta / Valletta
Activities:
Archaeological Site Visits, Small Ship Cruises
Activity Level:
Variable
Cruise around Sicily aboard the new luxury expedition ship Le Bougainville, while exploring mythical places at the crossroads of Eastern and Western civilizations. Discover Sicily's most beautiful historic cities and ancient sites. Valletta, the capital of Malta, is the departure point. Then, …
Cruise Details
0
Coast of Ortigia island at city of Syracuse
$4,840
EXPLORE

Ancient Jewels of the Mediterranean

Valletta - Athens - 8 Day Itinerary aboard Le Dumont-d'Urville
  • Meet a famous puppeteer in Syracuse
  • Immerse in Southern Italy
  • Wander through the ancient streets
Starts / Ends:
Valletta / Athens
Activities:
Archaeological Site Visits, Small Ship Cruises
Activity Level:
Relaxed
Embark on an enchanting 8-day Ancient Jewels of the Mediterranean cruise aboard Le Dumont-d'Urville. Starting in Valetta, indulge in included excursions at each port. Meet a famed puppeteer in Syracuse, explore quaint villages in Paros, and visit the historic Rodolico shipyard. Discover the …
Cruise Details
0
Ibiza
$3,640
EXPLORE

Grand Voyage: Malaga to Athens

16 Day Itinerary aboard Star Clipper
  • Visit Torres Park
  • Explore Valletta's beautiful garden
  • Wander in the city of Syracuse
  • Visit archaeological sites
Starts / Ends:
Malaga / Piraeus
Activity Level:
Variable
Enjoy a 16-day voyage through Spain aboard the Star Clipper, visiting some of the country's most beautiful spots. Depart from Malaga to Athens and visit the Parco Archeologico della Neapolis, one of Sicily's greatest archaeological sites. Observe that Mahon's heritage also includes the …
Cruise Details
0
Beautiful Taormina, Italy, with Mt. Etna in the background
$4,830
EXPLORE

Ancient Jewels of the Mediterranean

8 Day Itinerary aboard Le Bougainville
  • Meet a famous puppeteer in Syracuse
  • Immerse in Southern Italy
  • Wander through the ancient streets
  • Visit the Taormina in Sicily
Starts / Ends:
Valletta / Athens
Activities:
Archaeological Site Visits, Small Ship Cruises
Activity Level:
Variable
Embark on an enchanting 8-day Ancient Jewels of the Mediterranean cruise aboard Le Bougainville. Starting in Valetta, indulge in included excursions at each port. Meet a famed puppeteer in Syracuse, explore quaint villages in Paros, and visit the historic Rodolico shipyard. Discover the ancient …
Cruise Details
0
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