Panama Tours & Cruises in 2026

from $2,201

EXPLORE

Panama's Parks and Beaches

9 Day Itinerary

• Visit ruins of Old Panama
• Explore the Gailard Cut
• Pass the Bridge of the Americas
• Explore mountains and rural life

Starts / Ends

Panama City / Panama City

Activities

Wilderness Lodge Exploration

Activity Level

Relaxed

Choose a 9-day Panama National Parks and Beaches tour, and discover Old Panama ruins, iconic Canal views, lush waterfalls, and thrilling zip line adventures. Experience history, nature, and excitement in one unforgettable journey.

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from $2,488

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Panama Adventure

8 Day Itinerary

• Hike through tropical forest
• Take a coffee tour in Boquete
• Explore the Golf of Chiriqui
• Snorkel, kayak or hike

Starts / Ends

Panama City / Crowne Plaza Panama Airport

Activity Level

Easy Active

Discover unique wildlife in the vibrant jungles of western Panama as well as charming Caribbean towns through this comprehensive Panama tour. Explore the country through rainforest hikes, urban explorations, and snorkeling outings. Enjoy a remarkable and truly fresh cup of locally grown coffee at the end of the day!

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from $1,829

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Encounter Panama

7 Day Itinerary

• Explore El Valle's forested trails
• Transit through the Panama Canal
• Enjoy the Gamboa Rainforest Resort
• Visit the Embera community

Activity Level

Relaxed

Begin your Panama journey at the manmade marvel, the Panama Canal, and continue your travels into the region's tropical forests, visiting an indigenous community in Chagres National Park and exploring the ecology of Barro Colorado Island. This is a great introductory tour of Panama!

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from $3,276

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Discover Panama

8 Day Itinerary

• Trek the lowland tropical forest
• Bike, hike, zipline, raft or relax
• See wildlife in natural habitats
• Explore Tranquilo Bay

Activities

Biking

Activity Level

Easy Active

This 8-day hotel-based tour of Panama takes you from metropolitan Panama City, through the lowland tropical forest of Soberania National Park, snorkeling, kayaking, hiking, surfing, birding, and exploring Bocas del Toro & Tranquilo Bay, and finally to the Miraflores locks of the Panama Canal.

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from $2,829

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Caribbean Adventure - Bocas Town

8 Day Itinerary

• Raft down the Pacuare River
• Choose your days at Selva Bananito
• Snorkel the marine-rich coral reef
• Tour Panama's vibrant capital city

Activity Level

Easy Active

This 8-day land-based tour highlights the best of Costa Rica and Panama! Whitewater excitement and rainforest exploration in Costa Rica couple with relaxation amidst the turquoise waters of Panama for a perfectly paced vacation. Climb into the rainforest canopy, bask in the sunshine of Bocas del Toro, and fall into the rhythm of the Caribbean!

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from $3,788

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Caribbean Adventure

Tranquilo Bay - 9 Day Itinerary

• Raft down the Pacuare River
• Hike into the jungle for a swim
• Marvel at the Panama Canal
• Snorkel, kayak, hike, or relax

Activities

Whitewater Rafting

Activity Level

Easy Active

Experience the Caribbean from Costa Rica to Panama on this 9-day land-based adventure tour. Whitewater rafting and rainforest exploration along Costa Rica's Pacuare River combine with relaxation amidst the turquoise waters of Panama. Climb into the rainforest canopy, bask in the sunshine of Bocas del Toro, and snorkel & dive among the Caribbean reefs!

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from $6,507

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Luxury Panama Escape

9 Day Itinerary

• Mangrove kayaking in Bocas del Toro
• Explore optional excursions
• Tour Panama's vibrant capital city
• Visit Panama La Vieja

Starts / Ends

Panama City / Panama City

Activity Level

Relaxed

Discover Panama with our 9-day itinerary! Immerse yourself in the allure of Boquete's charming town, indulge in the unique experiences at Nayara Bocas del Toro, unwind on pristine beaches, and culminate your journey with a captivating Panama City tou

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from $6,420

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Panama and Costa Rica by Sea: The Natural Wonders of Central America – with Smithsonian Journeys

Colon - Puntarenas - 8 Day Itinerary aboard Le Champlain

• Discover San Blas
• Experience Panama Canal
• Explore Fuerte Amador
• Visit Darien National Park

Starts / Ends

Colon / Puntarenas

Activity Level

Variable

Join this 8-day cruise aboard Le Champlain to explore the natural wonders and cultural heritage of Panama and Costa Rica, including the white sands of Holandes Cayes, the iconic Panama Canal, and Panama City's historic Old Quarter.

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from $2,010

Air Credit

EXPLORE

Panama to Costa Rica

Balboa - Puerto Caldera - 8 Day Itinerary aboard Star Clipper

• Explore Balboa’s buildings
• Discover San Jose Island
• Snorkel Iguana Island’s clear water
• Encounter Coiba’s rare marine

Starts / Ends

Balboa / Puerto Caldera

Activity Level

Variable

Embark on an 8-day cruise from Balboa to Puerto Caldera aboard the Star Clipper, exploring highlights like San Jose Island and Coiba National Park. Enjoy diverse activities like snorkeling, surfing, and visiting Manuel Antonio National Park before disembarking in Puerto Caldera.

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from $6,150

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The Panama Canal, Pearl Islands and Darien Jungle

Southbound - 8 Day Itinerary aboard National Geographic Quest

• Transit the Panama Canal
• Explore Darien Jungle
• Visit Portobelo Forts
• Snorkel Pearl Islands

Starts / Ends

Panama City / Balboa

Activities

Urban Exploration

Activity Level

Variable

Embark on an 8-day Panama Canal cruise to the Pearl Islands and Darien Jungle aboard the National Geographic Quest. Transit the legendary Panama Canal, meet the Emberá people in Playa Muerto, spot wildlife in Punta Patiño, and snorkel the clear waters of the Pearl Islands, including Isla del Rey and Isla Pacheca.

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from $6,150

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The Panama Canal, Pearl Islands and Darien Jungle

Balboa to Colon - 8 Day Itinerary aboard National Geographic Quest

• Panama Canal transit
• Chagres River cruise
• Kayak and snorkel at Isla del Rey
• Explore Playa Muerto

Starts / Ends

Panama City / Panama City

Activities

Kayaking, Snorkeling, Wildlife Viewing, Village Visits, Hiking, Stand Up Paddle Boarding, Archaeological Site Visits

Activity Level

Variable

Explore Panama on an 8-day cruise aboard National Geographic Quest. Transit the Panama Canal, anchor in Gatun Lake, and discover Darien National Park and the Pearl Islands. Kayak, hike rainforests, snorkel reefs, and meet Embera communities in remote villages and protected reserves.

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from $3,840

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Tranquilo Bay Escape

8 Day Itinerary

• Navigate through Bocas archipelago
• Search for an array of wildlife
• Kayak around Boca del Toro
• Hike through the local jungle

Starts / Ends

Panama City / Panama City

Activity Level

Relaxed

Spend 8 days overlooking the Caribbean Sea from your private bungalow at a secluded casual resort. The days are yours to spend as you please. Choose from a menu of activity options each day or simply relax in the Caribbean sun.

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from $6,752

Save 20%

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Costa Rica and the Panama Canal

Eastbound - 8 Day Itinerary aboard National Geographic Quest

• Observe animals in their habitat
• Kayak through magical mangroves
• Transit the historical Panama Canal
• Explore Gulf of Panama beaches

Activities

Horseback Riding, Land & Sea Exploration

Activity Level

Variable

Discover Costa Rica & Panama on this wonderful 8-day expedition cruise aboard the National Geographic Quest. Venture into remote wilderness and hike among monkeys, sloths, and tropical birds, explore idyllic islands, snorkel over a vibrant coral reef, and take an expedition landing craft cruise through mangroves.

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from $10,170

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Secrets of Central America

Colón - Puntarenas - 11 Day Itinerary aboard Le Champlain

• Discover National Parks
• Sail through the Panama Canal
• Encounter with Emberas tribe
• Visit San Blas archipelago

Starts / Ends

Colon / Puntarenas

Activity Level

Variable

Join this 11-day Secrets of Central America cruise and explore Panama and Costa Rica, starting at San Lorenzo’s Fort and traveling from the Atlantic to the Pacific. Visit the San Blas Islands, the Pearl Islands, Darien National Park, and cross the Panama Canal. Meet local communities, and discover the biodiversity of Rio Esquinas and Curú Nature Reserve.

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from $1,087

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Portobelo Extension

4 Day Itinerary

• Snorkel in the bay of Portobelo
• Visit Aguas Clara Visitor Center
• Explore Gatun Lake busy waterway
• Visit UNESCO Portobelo Forts

Starts / Ends

Panama City / Panama City

Activity Level

Easy Active

Discover Panama's allure with a day exploring Aguas Clara, San Lorenzo Fort, and Portobelo's historic port. Snorkel along picturesque bays and witness colonial charm, designated a UNESCO Patrimony for Humanity.

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from $6,450

Save 20%

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Panama and Colombia: Exploring the Caribbean Coast

Panama to Cartagena - 8 Day Itinerary aboard National Geographic Quest

• Transit the Panama Canal
• Meet Indigenous people of Guna Yala
• Look for unique tropical wildlife
• See colonial architecture

Starts / Ends

Panama City / Cartagena

Activity Level

Variable

Discover an astonishing trove of natural and cultural treasures as you navigate the Caribbean coasts of Panama and Colombia on this 8-day cruise aboard the National Geographic Quest. Sail from Panama City to Cartagena, with stops in Portobelo, Guna Yala, Archipelago, and more.

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from $12,795

EBD

EXPLORE

Costa Rica and The Panama Canal

San Jose - Panama - 12 Day Itinerary aboard Sylvia Earle

• Cross Panama Canal
• Explore biodiverse rainforests
• Visit Coiba National Park
• Enjoy Manuel Antonio National Park

Starts / Ends

San Jose / Panama City

Activities

Rainforest Exploration

Activity Level

Variable

Embark on a 12-day cruise aboard the Sylvia Earle to explore Central America's rich ecosystems, from Costa Rica's diverse wildlife to Panama's vibrant coral reefs. Experience a memorable daylight transit through the historic Panama Canal, witnessing this engineering marvel firsthand.

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from $2,210

SS 25%

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Costa Rica & Panama

Puerto Caldera Roundtrip - 8 Day Itinerary aboard Star Clipper

• Discover Quepos's authentic charm
• Experience Golfito's allure
• Swim Bahia Potrero's calm waters
• Marvel at Arenal's majestic volcano

Starts / Ends

Puerto Caldera / Puerto Caldera

Activities

Ziplining, Small Ship Sailing

Activity Level

Variable

Set sail on an 8-day cruise aboard the Star Clipper through Costa Rica and Panama, exploring lush rainforests, pristine beaches, and vibrant marine life. Highlights include Manuel Antonio, Coiba Island, and Isla Tortuga’s turquoise waters.

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