Panama Tours & Cruises in 2025

from $2,314

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Panama's Parks and Beaches

9 Day Itinerary

• Visit ruins of Old Panama
• Explore the Gailard Cut
• Pass the Bridge of the Americas
• Explore mountains and rural life

Starts / Ends

Panama City / Panama City

Activities

Wilderness Lodge Exploration, Archaeological Site Visits

Activity Level

Relaxed

Choose a 9-day Panama National Parks and Beaches tour, and discover Old Panama ruins, iconic Canal views, lush waterfalls, and thrilling zip line adventures. Experience history, nature, and excitement in one unforgettable journey.

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from $2,608

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Panama Adventure

8 Day Itinerary

• Hike through tropical forest
• Take a coffee tour in Boquete
• Explore the Golf of Chiriqui
• Snorkel, kayak or hike

Starts / Ends

Panama City / Crowne Plaza Panama Airport

Activity Level

Easy Active

Discover unique wildlife in the vibrant jungles of western Panama as well as charming Caribbean towns through this comprehensive Panama tour. Explore the country through rainforest hikes, urban explorations, and snorkeling outings. Enjoy a remarkable and truly fresh cup of locally grown coffee at the end of the day!

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from $1,930

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Encounter Panama

7 Day Itinerary

• Explore El Valle's forested trails
• Transit through the Panama Canal
• Enjoy the Gamboa Rainforest Resort
• Visit the Embera community

Activity Level

Relaxed

Begin your Panama journey at the manmade marvel, the Panama Canal, and continue your travels into the region's tropical forests, visiting an indigenous community in Chagres National Park and exploring the ecology of Barro Colorado Island. This is a great introductory tour of Panama!

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from $3,590

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Discover Panama

8 Day Itinerary

• Trek the lowland tropical forest
• Bike, hike, zipline, raft or relax
• See wildlife in natural habitats
• Explore Tranquilo Bay

Activities

Biking

Activity Level

Easy Active

This 8-day hotel-based tour of Panama takes you from metropolitan Panama City, through the lowland tropical forest of Soberania National Park, snorkeling, kayaking, hiking, surfing, birding, and exploring Bocas del Toro & Tranquilo Bay, and finally to the Miraflores locks of the Panama Canal.

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from $2,828

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Caribbean Adventure - Bocas Town

8 Day Itinerary

• Raft down the Pacuare River
• Choose your days at Selva Bananito
• Snorkel the marine-rich coral reef
• Tour Panama's vibrant capital city

Activity Level

Easy Active

This 8-day land-based tour highlights the best of Costa Rica and Panama! Whitewater excitement and rainforest exploration in Costa Rica couple with relaxation amidst the turquoise waters of Panama for a perfectly paced vacation. Climb into the rainforest canopy, bask in the sunshine of Bocas del Toro, and fall into the rhythm of the Caribbean!

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from $3,787

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Caribbean Adventure

Tranquilo Bay - 9 Day Itinerary

• Raft down the Pacuare River
• Hike into the jungle for a swim
• Marvel at the Panama Canal
• Snorkel, kayak, hike, or relax

Activities

Whitewater Rafting

Activity Level

Easy Active

Experience the Caribbean from Costa Rica to Panama on this 9-day land-based adventure tour. Whitewater rafting and rainforest exploration along Costa Rica's Pacuare River combine with relaxation amidst the turquoise waters of Panama. Climb into the rainforest canopy, bask in the sunshine of Bocas del Toro, and snorkel & dive among the Caribbean reefs!

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from $7,145

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Luxury Panama Escape

9 Day Itinerary

• Mangrove kayaking in Bocas del Toro
• Explore optional excursions
• Tour Panama's vibrant capital city
• Visit Panama La Vieja

Starts / Ends

Panama City / Panama City

Activity Level

Relaxed

Discover Panama with our 9-day itinerary! Immerse yourself in the allure of Boquete's charming town, indulge in the unique experiences at Nayara Bocas del Toro, unwind on pristine beaches, and culminate your journey with a captivating Panama City tou

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from $1,960

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Panama to Costa Rica

Balboa - Puerto Caldera - 8 Day Itinerary aboard Star Clipper

• Explore Balboa’s buildings
• Discover San Jose Island
• Snorkel Iguana Island’s clear water
• Encounter Coiba’s rare marine

Starts / Ends

Balboa / Puerto Caldera

Activity Level

Variable

Embark on an 8-day cruise from Balboa to Puerto Caldera aboard the Star Clipper, exploring highlights like San Jose Island and Coiba National Park. Enjoy diverse activities like snorkeling, surfing, and visiting Manuel Antonio National Park before disembarking in Puerto Caldera.

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from $7,389

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The Panama Canal, Pearl Islands and Darien Jungle

Southbound - 8 Day Itinerary aboard National Geographic Quest

• Transit the Panama Canal
• Explore Darien Jungle
• Visit Portobelo Forts
• Snorkel Pearl Islands

Starts / Ends

Panama City / Balboa

Activities

Kayaking, Snorkeling, Wildlife Viewing, Urban Exploration, Village Visits, Hiking, Stand Up Paddle Boarding

Activity Level

Variable

Embark on an 8-day Panama Canal cruise to the Pearl Islands and Darien Jungle aboard the National Geographic Quest. Transit the legendary Panama Canal, meet the Emberá people in Playa Muerto, spot wildlife in Punta Patiño, and snorkel the clear waters of the Pearl Islands, including Isla del Rey and Isla Pacheca.

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from $3,327

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Tranquilo Bay Escape

8 Day Itinerary

• Navigate through Bocas archipelago
• Search for an array of wildlife
• Kayak around Boca del Toro
• Hike through the local jungle

Starts / Ends

Panama City / Panama City

Activity Level

Relaxed

Spend 8 days overlooking the Caribbean Sea from your private bungalow at a secluded casual resort. The days are yours to spend as you please. Choose from a menu of activity options each day or simply relax in the Caribbean sun.

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from $8,174

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Costa Rica and the Panama Canal

Eastbound - 8 Day Itinerary aboard National Geographic Quest

• Observe animals in their habitat
• Kayak through magical mangroves
• Transit the historical Panama Canal
• Explore Gulf of Panama beaches

Activities

Horseback Riding, Land & Sea Exploration

Activity Level

Variable

Discover Costa Rica & Panama on this wonderful 8-day expedition cruise aboard the National Geographic Quest. Venture into remote wilderness and hike among monkeys, sloths, and tropical birds, explore idyllic islands, snorkel over a vibrant coral reef, and take an expedition landing craft cruise through mangroves.

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from $820

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Portobelo Extension

4 Day Itinerary

• Snorkel in the bay of Portobelo
• Visit Aguas Clara Visitor Center
• Explore Gatun Lake busy waterway
• Visit UNESCO Portobelo Forts

Starts / Ends

Panama City / Panama City

Activity Level

Easy Active

Discover Panama's allure with a day exploring Aguas Clara, San Lorenzo Fort, and Portobelo's historic port. Snorkel along picturesque bays and witness colonial charm, designated a UNESCO Patrimony for Humanity.

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from $6,450

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Panama and Colombia: Exploring the Caribbean Coast

Panama to Cartagena - 8 Day Itinerary aboard National Geographic Quest

• Transit the Panama Canal
• Meet Indigenous people of Guna Yala
• Look for unique tropical wildlife
• See colonial architecture

Starts / Ends

Panama City / Cartagena

Activity Level

Variable

Discover an astonishing trove of natural and cultural treasures as you navigate the Caribbean coasts of Panama and Colombia on this 8-day cruise aboard the National Geographic Quest. Sail from Panama City to Cartagena, with stops in Portobelo, Guna Yala, Archipelago, and more.

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from $1,930

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Costa Rica to Panama

Puerto Caldera - Balboa - 8 Day Itinerary aboard Star Clipper

• Explore Puerto Caldera’s coast
• Relax on Isla Tortuga’s beaches
• Experience Golfito’s rich history
• Snorkel in Golfo de Chiriqui’s

Starts / Ends

Puerto Caldera / Balboa

Activities

Ziplining

Activity Level

Variable

Set sail on an 8-day cruise aboard the Star Clipper, starting in Puerto Caldera, Costa Rica. Explore stunning beaches, vibrant marine parks, and rich history before concluding your adventure in Balboa, Panama.

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from $1,960

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Costa Rica & Panama

Puerto Caldera Roundtrip - 8 Day Itinerary aboard Star Clipper

• Discover Quepos's authentic charm
• Experience Golfito's allure
• Swim Bahia Potrero's calm waters
• Marvel at Arenal's majestic volcano

Starts / Ends

Puerto Caldera / Puerto Caldera

Activity Level

Variable

Set sail on an 8-day cruise aboard the Star Clipper through Costa Rica and Panama, exploring lush rainforests, pristine beaches, and vibrant marine life. Highlights include Manuel Antonio, Coiba Island, and Isla Tortuga’s turquoise waters.

Cruise Details

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from $4,450

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Barbados to Panama

15 Day Itinerary aboard Royal Clipper

• Explore Bridgetown, Barbados
• Enjoy Grenada's unique aromas
• Discover Dutch colonial Curacao
• Transit the historic Panama Canal

Starts / Ends

Bridgetown / Balboa

Activity Level

Variable

Starting at the Caribbean port of Bridgetown, this 15-day cruise aboard the Royal Clipper sails through the turquoise Caribbean waters en route to the Panama Canal, visiting Grenada, Bonaire, Curacao, Aruba, and Colombia along the way. Explore the tropical jungles, snorkel in vibrant reefs, immerse yourself in tribal culture, and marvel at the Panama Canal.

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from $4,450

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Panama to Antigua

15 Day Itinerary aboard Royal Clipper

• Explore Balboa’s colonial charm
• Transit Panama’s iconic canal
• Discover San Blas culture
• Enjoy Aruba’s clear waters

Starts / Ends

Balboa / St. John's

Activities

Local Market Visits

Activity Level

Variable

Set sail on a 15-day Royal Clipper cruise from Balboa, Panama, featuring a full Panama Canal transit and visits to the San Blas Islands, Cartagena, and the Caribbean gems of Aruba, Curacao, and Bonaire. Experience lush Grenada and volcanic St. Lucia, and finish your journey in Antigua, all while enjoying elegant sailing and stunning island views.

Cruise Details

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from $12,955

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Natural Wonders, Engineering Marvels

Puntarenas - Colon - 13 Day Itinerary aboard Sea Cloud Spirit

• Explore Nicoya Peninsula beaches
• Visit Pearl Islands Discover Pea
• Discover Marina Flamingo
• Relax at Playa Panama
• Sail through the Panama Canal

Starts / Ends

Puntarenas / Colon

Activities

Rainforest Exploration, Small Ship Sailing, Fishing

Activity Level

Variable

Experience the essence of “Pura Vida” on a 13-day Panama cruise from Puntarenas to Colon. Visit Punta Leona, Marina Flamingo, Playa Panama, Quepos, Puerto Jimenez, the Pearl Islands, and the San Blas Archipelago, exploring rainforests, beaches, & marinas while encountering diverse wildlife and witnessing the engineering marvel of the Panama Canal.

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